Most cited

High level of Pan Lysine Lactylation (Pan-Kla) is found in pancreatic cancer tissues.

H3K18la levels are increased in pancreatic cancer tissues.

H3K18la is related to the severity and prognosis of pancreatic cancer.

Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

With correct screening and diagnosis, treatment must be offered to improve prognosis.

Adequate treatment in a healthcare setting must be known.

The Early Start Denver Model (ESDM) showed improvements in the cognitive, verbal, and social aspects.

Time occasionally can improve some scores independently of the group.

Pembrolizumab is effective for GTN multi-drug resistant treatment.

Pembrolizumab seems also effective for PSTT/ETT treatment.

Pembrolizumab efficacy is similar in cases of resistance or GTN relapse.

Colorectal cancer is one of the most common neoplasms and a leading cause of cancer-related mortality worldwide.

The treatment of colorectal neoplasia has evolved significantly over the past few decades due to advances in minimally invasive techniques.

Although conventional surgery remains the gold standard for rectal tumors, ESD, TEM, and TAMIS emerged as effective and less invasive therapies for benign tumors and early cancers without nodal metastases, allowing lower morbidity.

ESD and TES are safe and effective treatment options for early-stage rectal tumors.

Cisplatin induces RBBP4 in A549 cells, higher in cisplatin-resistant A549/DDP.

Downregulating RBBP4 with siRNA increased cisplatin sensitivity in A549 and A549/DDP.

Overexpressing RBBP4 reduced sensitivity, while downregulation inhibited cyclinD1.

CyclinD1 overexpression reversed this effect in A549, A549/DDP, and HeLa/DDP cells.

LCA has the ability to suppress the growth, movement, and invasion of glioma cells.

It can also counteract resistance to TMZ drugs.

This opens up new possibilities for identifying clinical drugs to treat glioma patients who are resistant to TMZ.

Heart failure cohort analysis using the MIMIC-III database of 6094 patients.

Impact of clinical factors on heart failure prognosis and patient outcomes.

Exploring biomarkers associated with heart failure progression and mortality.

Data-driven insights into heart failure management from ICU patient data.

Predictive modeling of heart failure outcomes based on the MIMIC-III dataset.

Molecular and IHC markers aid in objective classification and outcome prediction of PT.

Surgery is the gold standard for PT, but margin extent lacks consensus.

Local recurrence is key in PT prognosis, with margin status as the main risk factor.

Adjuvant radiotherapy lowers recurrence in borderline/malignant PTs with close margins.