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Most cited

Data available in articles published since the year 2017

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Glutathione effect on functional and histological recovery after spinal cord injury in rats
Fernando Flores de Araujo, Raphael Martus Marcon, Alexandre Fogaça Cristante, Tarcísio Eloy Pessoa Barros Filho
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Highlights

  • Glutathione is important in protecting secondary spinal cord injury from oxidative stress.

  • As the secondary injury progresses, depletion in its reduced form occurs.

  • Using glutathione in traumatic spinal cord injury could help control the neurological injury.

  • In an experimental setting, the use of glutathione provided better functional scores after traumatic spinal cord injury.

Full text access
Available online 1 January 2024
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Parkinson's disease inpatient mortality: Attention to sudden death
Tomás de la Rosa, Fúlvio Alexandre Scorza
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Full text access
Available online 1 January 2024
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Toll-like receptor signaling pathway involved in pathogenesis of thromboangiitis obliterans through activating of NF-κB
Facai Guo, Yan Bi, Jiangyan Yin, Yi Guo
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Full text access
Available online 1 January 2024
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MicroRNA-1258 suppresses oxidative stress and inflammation in septic acute lung injury through the Pknox1-regulated TGF-β1/SMAD3 cascade
XiaoMeng Xu, XiaoHong Xu, JinLiang Cao, LuoYang Ruan
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Highlights

  • MiR-1258 is downregulated in septic ALI.

  • MiR-1258 inhibits inflammation and oxidative stress via Pknox1 in ALI.

  • MiR-1258 targets Pknox1 to control TGF-β1/SMAD3 cascade.

Full text access
Available online 1 January 2024
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FOXO3a deregulation in uterine smooth muscle tumors
Thais Gomes de Almeida, Anamaria Ritti Ricci, Laura Gonzalez dos Anjos, Jose Maria Soares Junior, Gustavo Arantes Rosa Maciel, Edmund Chada Baracat, Katia Candido Carvalho
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Highlights

  • Higher FOXO3a levels suggest a link to malignancy in Uterine Smooth Muscle Tumors.

  • Elevated expression of FOXO3a is connected to LMS prognosis, indicating it is a survival marker.

  • MiRNA activity contributes to the imbalance of FOXO3a in Uterine Smooth Muscle Tumors.

Full text access
Available online 1 January 2024
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Prognostic model on pregnancy outcomes for women with recurrent spontaneous abortions treated with cyclosporin A: A single-institution experience
Ze-Ming Zhang, Na Zhang, Xiao-Fei Wang
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Highlights

  • The prognostic model for pregnancy outcomes was constructed.

  • The prognostic factors included age, ANA, and anti-β2 glycoprotein I antibody levels.

  • The prognostic models showed higher value for predicting pregnancy success.

Full text access
Available online 1 January 2024
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Evaluation of the RAPID score as a predictor of postoperative morbidity and mortality in patients undergoing pulmonary decortication for stage III pleural empyema
Danilo Caribé Carneiro, Paula Duarte D'Ambrosio, Alessandro Wasum Mariani, Jaqueline Schaparini Fonini, Gabriela Ketherine Zurita Aguirre, João Pedro Carneiro Leão, Aurelino Fernandes Schmidt Júnior, Eihab O. Bedawi, ... Paulo Manuel Pêgo-Fernandes
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Highlights

  • This study establishes a strong correlation between the RAPID score and 3-month mortality in patients undergoing lung decortication for pleural empyema.

  • Patients were stratified into low, medium, and high-risk groups based on the RAPID score, demonstrating that this approach can be valuable in identifying patients with a higher likelihood of complications. This can inform treatment planning and post-operative monitoring.

  • While the results suggest a strong correlation, prospective studies are needed to fully validate the use of the RAPID score in this population. This underscores the importance of future clinical research to enhance the selection of the initial treatment for patients with pleural empyema.

Full text access
Available online 1 January 2024
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Could immunotherapy be a hope for addiction treatment?
Maria Carolina Machado da Silva, Luiz Philipe de Souza Ferreira, Amanda Della Giustina
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Full text access
Available online 1 January 2024
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Comparative analysis of primary health care attributes between children under and over 3 years of age using the primary care assessment tool
Luciana Harumi Miranda Omori, Deoclecio Avigo, Itamar de Souza Santos, Gustavo Diniz Ferreira Gusso, Maria Teresa Bechere Fernandes
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Highlights

  • Government programs primarily focus on early childhood.

  • Primary Care services tend to be better for children under three years old.

  • New programs are needed to provide follow-up care for children beyond early childhood.

Full text access
Available online 1 January 2024
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Surgical complications in the first and second semesters of the general surgery medical residence. A study of 14063 cases
Bruno Henrique Alvarenga, Izabel Cristina Rios, Francisco de Salles Collet e Silva, Edivaldo Massazo Utiyama
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Highlights

  • Surgical complications increase after the entry of new resident doctors.

  • Second-year resident doctors need more training time.

  • The increase in surgical complications is associated with the entry of new resident doctors, but also with the progression from the first to the second year of the course.

Full text access
Available online 1 January 2024
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