14 antidepressants show a significant seizure risk association in the FAERS analysis.

Bupropion shows the strongest seizure signal with the highest reporting odds ratio.

TCAs/tetracyclics elevate seizure risk, particularly clomipramine and maprotiline.

SSRIs/SNRIs require safety reconsideration as seizure risk persists.

Mirtazapine is linked to seizure risk despite low initial reports.

Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

With correct screening and diagnosis, treatment must be offered to improve prognosis.

Adequate treatment in a healthcare setting must be known.

The Early Start Denver Model (ESDM) showed improvements in the cognitive, verbal, and social aspects.

Time occasionally can improve some scores independently of the group.

Mitochondria regulate cellular functions, and mtDNA mutations can affect metabolism.

mtDNA mutations are promising biomarkers for cancer detection and tumor progression.

These mutations might influence therapy response, drug resistance, and patient outcomes.

Tools and models advance precision oncology and mitochondrial-targeted treatments.

There is no consensus about which method is preferred for biliary drainage for Perihilar Cholangiocarcinoma (PCCA).

Endoscopic retrograde cholangiopancreatography (EBD) or Percutaneous Transhepatic Biliary Drainage (PTBD) are options of choice.

PTBD is superior to EBD regarding crossover rate, overall post-drainage complications, and post-drainage pancreatitis.

EBD is superior to PTBD when it comes to hospital length of stay.

For the palliation of PCCA, PTBD is superior to EBD in terms of clinical success and post-drainage cholangitis.

Homeopathy is based on four heterodox and complementary scientific assumptions.

Pseudoskeptics deny these assumptions and any scientific evidence that proves them.

The e-book proves the scientific evidence for homeopathy.

The e-book describes hundreds of experimental and clinical studies in homeopathy.

The e-book demystifies the fallacy that “homeopathy is placebo effect”.

Some refractory gastroesophageal reflux disease patients have shown a poor response to traditional treatment options.

Optimization of drug therapy, endoscopic therapy, surgical procedures, and traditional Chinese medicine treatment are the main treatment strategies currently.

Individualized treatment plans should be explored for future research.

This meta-analysis shows that gefitinib plus chemotherapy showed significantly better efficacy in improving objective response rate, disease control rate, progression-free survival, and OS as compared with gefitinib alone.

Similar efficacy of gefitinib plus chemotherapy is found in the sub-population with positive EGFR mutation.

The toxicity of gefitinib plus chemotherapy is also increased but within clinical management.