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Clinics
Clinics
ISSN: 1807-5932
e-ISSN: 1980-5322

Clinics is a gold open access electronic international journal that publishes peer-reviewed research in continuous flow of interest to clinicians and researchers in medical and biomedical sciences based on its originality, importance, conclusions and interest to readers. CLINICS also publishes Comments and Editorials. The journal is committed to the principles of ethics, respect for the individual, humanization, honesty, pioneering spirit and excellence.Clinics is the Official Scientific journal of Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP).

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Indexed in:

Medline, Directory of Open Access Journals (DOAJ), PubMed Central (PMC), Science Citation Index Expanded (SCIE)

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Impact factor

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.

© Clarivate Analytics, Journal Citation Reports 2025

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Impact factor 2024
2.4
Citescore

CiteScore measures average citations received per document published.

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Citescore 2024
3.4
SJR

SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.

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SJR 2024
0.612
SNIP

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

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SNIP 2024
0.752
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Issue
portada-S1807593225X00028Vol. 81. (In progress)
(January - December 2026)
This issue is in progress but contains articles that are final and fully citable.
Original articles
The role of SIGLEC9 in immunosuppression and prognosis in cervical cancer
Bihui Wang, Yuejie Zhu, Zhenyu Ru, Yulian Zhang, Mingkai Yu, Pingfen Li, Manli Zhang, Jianbing Ding, Zhifang Chen
Clinics. 2026;81C:100849
Highlights

  • SIGLEC9 is highly expressed in cervical cancer and linked to poor prognosis.

  • Bioinformatics show SIGLEC9 correlates with macrophages and T-cells.

  • SIGLEC9+ TAMs and T-cells are highly enriched in the cervical cancer microenvironment.

  • High SIGLEC9+ TAM expression correlates with poor prognosis in cervical cancer.

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Electrophysiological evaluation of the auditory pathway in newborns and infants with peri-intraventricular hemorrhage and/or periventricular leukomalacia
Rosanna Giaffredo Angrisani, Natalia Olival Balzarini, Carla Regina Tragante, Valdenise Martins Laurindo Tuma Calil, Werther Brunow de Carvalho, Carla Gentile Matas
Clinics. 2026;81C:100853
Highlights

  • Prematurity is a risk factor for lifelong hearing damage.

  • Hearing monitoring is necessary until around 3-years of age.

  • Hearing monitoring after peri-intraventricular hemorrhage is essential.

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New population-specific cephalic index standards for Malaysian subadults: prevalence, growth patterns, and clinical implications from a CT imaging study
Sharifah Nabilah Syed Mohd Hamdan, Rabi’ah Al-Adawiyah Rahmat, Selva Malar Munusamy, Norliza Ibrahim
Clinics. 2026;81C:100855
Highlights

  • Establishes the first cephalic index standards for multi-ethnic Malaysian subadults.

  • Reports a negative correlation between age and CI, with a decline of 0.026 yearly.

  • Shows higher CI values in Malaysians than in Caucasians and other Asian groups.

  • Provides a validated tool (ICC > 0.93) to track cranial growth and deformity severity.

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Head and neck cancer patients present late cancer cachexia two years after curative chemoradiotherapy
Willian das Neves, Thomás Giollo Rivelli, Eduardo Furquim Simão, Marco Aurélio Vamondes Kulcsar, Gilberto de Castro Junior
Clinics. 2026;81C:100851
Highlights

  • Two diagnostic criteria diagnose cancer cachexia in HNSCC patients.

  • Disease-free HNSCC patients present cancer cachexia after long-term follow-up.

  • Cachexia is not associated with dysphagia.

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Review articles
C-reactive protein in adult sepsis: systematic review and meta-analysis
Antonio Silvinato, Clara Lucato dos Santos, Eliane Amorim, Idevaldo Floriano, Luís Eduardo Miranda Paciência, Luca Schiliró Tristão, Wanderley Marques Bernardo
Clinics. 2026;81C:100848
Highlights

  • CRP shows high sensitivity but low specificity for adult sepsis diagnosis.

  • Diagnostic accuracy of CRP in sepsis is limited by high heterogeneity.

  • Prognostic value of CRP for mortality in sepsis remains uncertain.

  • False-positive rate of CRP in sepsis diagnosis reaches about 44 %.

  • Overall quality of evidence on CRP use in sepsis is low.

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