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Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) PET/CT calibration for post-treatment standard body scan acquisition with yttriu...
Journal Information
Vol. 41. Issue 6.
Pages 368-372 (November - December 2022)
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Vol. 41. Issue 6.
Pages 368-372 (November - December 2022)
Original Article
PET/CT calibration for post-treatment standard body scan acquisition with yttrium-90 resin micro-SPHERES
Calibración de PET/TC para adquisición de estudio de cuerpo estándar postratamiento con esferas de resina de ytrio-90
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5
J.A. Uña-Gorospea,
Corresponding author
junagor@gobiernodecanarias.org

Corresponding author.
, C. Baso-Pérezb, C. Cárdenas-Negroc, J.A. Merino-Gestosod, B.C. Portas-Ferradáse, A. Allende-Rieraf
a Nuclear Medicine Department, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain
b Radiology Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Islas Canarias, Spain
c Nuclear Medicine Department, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain
d Physicist, Medical Physics Department, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain
e Physicist, Medical Physics Department, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain
f Nuclear Medicine Department, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain
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Abstract
Introduction

Among the objectives in treatments with yttrium-90 spheres, is to demonstrate that the tumoricidal dose is achieved and that hepatotoxic doses are avoided, as well as that there is no extrahepatic deposition.

Material and methods

We use different amounts of yttrium-90 resin micro-spheres and a NEMA NU2-2007 phantom to check if the scanner maintains a response that allows real dosimetric calculations.

Results

The Gemini tomograph responds linearly in a wide range of activities with R2 = 0.9983.

Conclusion

The detection capacity of the PET equipment allows us to carry out standard body studies with dosimetric purposes with times of five minutes per bed. It also make possible to verify the absence of extrahepatic deposition of significant amounts of yttrium 90 spheres.

Keywords:
PET
Resin spheres
Yttrium-90
SIR-Spheres
Calibration
Resumen
Introducción

Entre los objetivos en los tratamientos con esferas marcadas con ytrio-90, figura demostrar que se consigue la dosis tumoricida y que se evitan dosis hepatotóxicas, así como que no existe deposición extrahepática.

Material y métodos

Utilizamos diferentes cantidades de ytrio y un maniquí NEMA NU2-2007 para comprobar si el tomógrafo mantiene una respuesta que permita hacer cálculos dosimétricos reales.

Resultados

El tomógrafo Gemini responde de manera lineal en un rango amplio de actividades con una R2 = 0.9983.

Conclusión

La capacidad de detección del equipo PET nos permite realizar estudios de cuerpo estándar con finalidad dosimétrica con tiempos de cinco minutos por bed que además hacen posible verificar la ausencia de deposición extrahepática de cantidades significativas de esferas de ytrio 90.

Palabras clave:
PET
Esferas de resina
Ytrio 90
SIR-Spheres
Calibración

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