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Sexual dysfunction is a common side effect of antidepressants, especially in women.

Identifying effective pharmacological treatments for Antidepressant-Induced Sexual Dysfunction (AISD) is crucial for enhancing patient quality of life.

Bupropion at a dose of 150 mg has shown greater effectiveness in treating AISD in women.

The meta-analysis found no direct correlation between improvements in sexual function and reductions in depressive symptoms.

Molecular and IHC markers aid in objective classification and outcome prediction of PT.

Surgery is the gold standard for PT, but margin extent lacks consensus.

Local recurrence is key in PT prognosis, with margin status as the main risk factor.

Adjuvant radiotherapy lowers recurrence in borderline/malignant PTs with close margins.

14 antidepressants show a significant seizure risk association in the FAERS analysis.

Bupropion shows the strongest seizure signal with the highest reporting odds ratio.

TCAs/tetracyclics elevate seizure risk, particularly clomipramine and maprotiline.

SSRIs/SNRIs require safety reconsideration as seizure risk persists.

Mirtazapine is linked to seizure risk despite low initial reports.

ω−3 PUFAs had no significant effect on endometriosis symptoms, such as pain, etc.

ω−3 PUFAs could reduce the inflammatory response in patients with endometriosis.

The local environment of implants exhibits pre-inflammatory tissue characteristics.

Abnormal Uterine Bleeding (AUB) is the leading cause of seeking gynecological care, with data showing that 3 in 10 Brazilian women have this condition, with intermenstrual bleeding standing out.

According to the International Federation of Gynecology and Obstetrics (FIGO), cycles lasting less than 24 days or more than 38 days, with menstrual flow lasting eight days or more and blood loss reported by the woman as intense, are considered abnormal.

The main causes of AUB are summarized in the mnemonic PALM-COEIN, dividing them into structural and non-structural causes.

Diagnosing the etiology of AUB is essential to establish specific treatments, directed at the cause, which can be clinical or surgical, aiming not only to control the amount of blood loss, but also to improve the quality of life of women with AUB.

In general, the first line of treatment for AUB is medication, with surgical treatment being intended for failure or contraindication to clinical treatment or in cases of significant hemodynamic instability.

Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

With correct screening and diagnosis, treatment must be offered to improve prognosis.

Adequate treatment in a healthcare setting must be known.

The Early Start Denver Model (ESDM) showed improvements in the cognitive, verbal, and social aspects.

Time occasionally can improve some scores independently of the group.

Diagnosis and etiology of POI.

Hormone therapy as an essential treatment.

Fertility preservation strategies.

Long-term monitoring and multidisciplinary care.

Androgen therapy for sexual dysfunction.

Normal ranges of fetal weight as a function of gestational age was created.

New parameter, days before birth, was incorporated for normal ranges of fetal weight.

Parameter days before birth is useful for estimating fetal weight at scheduled birth.

This study was designed to assess melatonin in severe-to-critical COVID-19.

Melatonin significantly reduced in-hospital mortality.

Melatonin should be considered for severe-to-critical COVID-19 patients.

Heart failure cohort analysis using the MIMIC-III database of 6094 patients.

Impact of clinical factors on heart failure prognosis and patient outcomes.

Exploring biomarkers associated with heart failure progression and mortality.

Data-driven insights into heart failure management from ICU patient data.

Predictive modeling of heart failure outcomes based on the MIMIC-III dataset.

The total effective rate of treatment in the observation group was higher than that in the control group.

The middle ear resonance frequency of the children in the observation group was higher than that of the control group at weeks 4, 8 and 12 of treatment, and the air-conduction hearing threshold was lower than that of the control group.

The total effective rate of the observation group after 12 weeks of treatment was 92.11 %, which was significantly higher than that of the control group (73.68 %).

The T-ETDQ score of the observation group was lower than that of the control group after treatment.

Mitochondria regulate cellular functions, and mtDNA mutations can affect metabolism.

mtDNA mutations are promising biomarkers for cancer detection and tumor progression.

These mutations might influence therapy response, drug resistance, and patient outcomes.

Tools and models advance precision oncology and mitochondrial-targeted treatments.

Errors during patient care are a huge source of ethical, financial, and even mental problems affecting patients, physicians, and healthcare organizations.

Open disclosure is a process for ensuring that open, honest, empathic and timely discussions occur between patients and/or their support person(s) and healthcare staff following a patient safety incident.

Physicians may avoid or hide errors or blame other health professionals.

Adopting an effective disclosure system, increases the possibility of an agreement between the parties involved, meaning significant savings in financial resources.

Patients want some attitudes from their doctors: an explicit statement that an error occurred and an apology.

Mammographic density impacts the primary screening process, as dense tissue may mask tumors, resulting in false-negative results.

Mammographic density is known to be a risk factor for breast cancer, associated with a 1- to 6-fold increase in the incidence of this disease.

In women at average risk, going to annual screening mammography at age 40 has demonstrated a reduction in breast cancer mortality by roughly 20 %.

For women at intermediate and high-risk, supplementary modalities such as magnetic resonance imaging, ultrasound, tomosynthesis, and molecular breast imaging may be considered for enhanced screening to increase detection rates.

Randomized controlled trial with 4-week follow-up.

Supervised ACTs improve short-term outcomes in infants with AVB.

ACTs reduce clinical symptoms in viral bronchiolitis.

Respiratory rate and retractions improved with physiotherapy.

PSE showed greater ABSS and SpO2 improvements vs. AAD and control.

Leukoreduction decreases the adverse effects of blood component transfusion.

Leukoreduction by pre-storage filtration reduced the length of hospital stay.

Leukoreduction by pre-storage filtration reduced hospital deaths.

No effect of leukoreduction filtration moment on adverse transfusion reaction.

No effect of leukoreduction filtration moment on healthcare-associated infection.

Urinary incontinence is observed as the main post-prostatectomy complication.

Pelvic floor rehabilitation is the first-line treatment for urinary incontinence.

Electromyography biofeedback instructs the patient on the correct activation muscle.