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Clinics Most often read
Journal Information

Most often read

29944
Long post-COVID-vaccination syndrome manifesting as temperature-sensitive myalgia and hyper-CKemia
Josef Finsterer, Carla A. Scorza, Fulvio A. Scorza
Clinics. 2023;78C:100175
29944
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21030
“Scientific Evidence for Homeopathy”
Marcus Zulian Teixeira
Clinics. 2023;78C:100255
21030
Highlights

  • Homeopathy is based on heterodox and complementary four scientific assumptions.

  • Pseudosceptics deny these assumptions and any scientific evidence that proves them.

  • The dossier describes hundreds of clinical and experimental studies in homeopathy.

  • The dossier demystifies the fallacy that “there isn't scientific evidence for homeopathy”.

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15097
Efficacy, safety, and potential industry bias in using deoxycholic acid for submental fat reduction ‒ A systematic review and meta-analysis of randomized clinical trials
Gabriel Santiago Giuglio Inocêncio, Daniela Meneses-Santos, Marcelo Dias Moreira de Assis Costa, Walbert A. Vieira, Vinicius Lima de Almeida, Renata Prata Cunha Bernardes Rodrigues, Sigmar de Mello Rode, Luiz Renato Paranhos
Clinics. 2023;78C:100220
15097
Highlights

  • Deoxycholic acid is effective in submental fat reduction for both clinician and patient-related outcomes.

  • Well-tolerated side-effects were observed in Deoxycholic acid groups.

  • All eligible randomized trials showed a potential industry bias.

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12193
SARS-CoV-2 vaccination complicated by small fiber neuropathy, mast cell activation syndrome, and pericarditis
Danice Hertz, Fulvio Alexandre Scorza, Ana Claudia Fiorini, Josef Finsterer
Clinics. 2023;78C:100304
12193
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9984
Small fiber neuropathy with long-term, multifocal paresthesias after a SARS-CoV-2 vaccination
Josef Finsterer, Fulvio Alexandre Scorza, Carla Alexandra Scorza, Antonio-Carlos G. de Almeida
Clinics. 2023;78C:100186
9984
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9608
Venous thromboembolism risk score during hospitalization in pregnancy: results of 10694 prospective evaluations in a clinical trial
Venina Isabel Poço Viana Leme de Barros, Ana Maria Kondo Igai, Fernanda Spadotto Baptista, Maria Rita de Figueiredo Lemos Bortolotto, Stela Verzinhasse Peres, Rossana Pulcinelli Vieira Francisco
Clinics. 2023;78C:100230
9608
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8918
Understanding the journey of patients with depression in Brazil: A systematic review
Alexandrina Meleiro, Chei Tung Teng, Frederico Navas Demetrio, Vivian Cardoso Batista, Luiz Fernando Vieira, Paola Marina Elorza
Clinics. 2023;78C:100192
8918
Highlights

  • Depression in Brazil.

  • Patient journey stages.

  • Awareness.

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7738
The pituitary gland in SARS-CoV-2 infections, vaccinations, and post-COVID syndrome
Josef Finsterer, Fulvio Alexandre Scorza
Clinics. 2023;78C:100157
7738
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7608
Complete blood count and C-reactive protein to predict positive blood culture among neonates using machine learning algorithms
Felipe Yu Matsushita, Vera Lúcia Jornada Krebs, Werther Brunow de Carvalho
Clinics. 2023;78C:100148
7608
Highlights

  • It can take days to get the result of blood culture.

  • CBC and CRP are readily available exams and could be used to predict blood culture.

  • ML algorithms based on CBC and CRP couldn't predict neonatal blood culture positivity.

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6398
Bioethics and xenotransplantation from pig to human
Flavio Henrique Ferreira Galvao, Max Grinberg
Clinics. 2023;78C:100170
6398
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6001
The effect of sperm DNA fragmentation on in vitro fertilization outcomes of unexplained infertility
Qingxin Wang, Xiaoling Gu, Yannan Chen, Minyan Yu, Lingna Peng, Shuping Zhong, Xia Wang, Jinxing Lv
Clinics. 2023;78C:100261
6001
Highlights

  • Infertility is caused by heterogeneous risks, but most of them are unexplained.

  • Sperm DFI diagnostic value was controversial as not rule out male sperm parameters.

  • Whether DFI was a useful indicator for embryologists and clinicians in UEI couples.

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5341
Polyethylene glycol combined with lactulose has better efficacy than polyethylene glycol alone in bowel preparation before colonoscopy: A meta-analysis
Xiaofen Zhang, Yishu Chen, Ye Chen, Wei Zhu, Chenxi Tang, Shelby Lamm, Lan Li
Clinics. 2023;78C:100172
5341
Highlights

  • High quality of bowel cleansing is important to the accuracy of diagnosis and the safety of treatment in colonoscopy.

  • PEG combined with lactulose has a better efficacy in bowel preparation than PEG alone.

  • PEG combined with lactulose has fewer adverse reactions than PEG alone in bowel preparation.

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5053
Endoscopic Biliary Darinage (EBD) versus Percutaneous Transhepatic Biliary Drainage (PTBD) for biliary drainage in patients with Perihilar Cholangiocarcinoma (PCCA): A systematic review and meta-analysis
Caroline Flaksbaum Moll, Diogo Turiani Hourneaux de Moura, Igor Braga Ribeiro, Igor Mendoça Proença, Epifanio Silvino do Monte Junior, Sergio A. Sánchez-Luna, Maria Fernanda Shinin Merchán, Josselyn Mariana Vera Intriago, ... Eduardo Guimarães Hourneaux de Moura
Clinics. 2023;78C:100163
5053
Highlights

  • There is no consensus about which method is preferred for biliary drainage for Perihilar Cholangiocarcinoma (PCCA).

  • Endoscopic retrograde cholangiopancreatography (EBD) or Percutaneous Transhepatic Biliary Drainage (PTBD) are options of choice.

  • PTBD is superior to EBD regarding crossover rate, overall post-drainage complications, and post-drainage pancreatitis.

  • EBD is superior to PTBD when it comes to hospital length of stay.

  • For the palliation of PCCA, PTBD is superior to EBD in terms of clinical success and post-drainage cholangitis.

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4855
Neurophysics: Understanding brain activity with modeling complex systems mathematics
Fulvio A. Scorza, Ana C. Fiorini, Antônio M. Rodrigues, Carla A. Scorza, Gabriel D. Vilallonga, Marcelo A. Moret, Tarcísio M. Rocha Filho, Josef Finsterer, Antônio-Carlos G. de Almeida
Clinics. 2023;78C:100158
4855
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4779
The effectiveness of ultrasound-guided core needle biopsy in detecting lymph node metastases in the axilla in patients with breast cancer: systematic review and meta-analysis
Qi Xu, Jiale Wang, Jing Wang, Runzhao Guo, Yao Qian, Feng Liu
Clinics. 2023;78C:100207
4779
Highlights

  • US-CNB is a reliable preoperative test for detecting axillary metastasis in breast cancer patients, with high accuracy and safety.

  • Compared to US-FNA, US-CNB shows even higher accuracy for detecting axillary metastasis in breast cancer patients.

  • The use of US-CNB as a preoperative test can reduce the need for a second operation and improve patient outcomes.

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4049
Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non‑small‑cell lung cancer: A meta analysis
Min Yi, Ting He, Kaijin Wang, Yonggang Wei
Clinics. 2023;78C:100152
4049
Highlights

  • This meta-analysis shows that gefitinib plus chemotherapy showed significantly better efficacy in improving objective response rate, disease control rate, progression-free survival, and OS as compared with gefitinib alone.

  • Similar efficacy of gefitinib plus chemotherapy is found in the sub-population with positive EGFR mutation.

  • The toxicity of gefitinib plus chemotherapy is also increased but within clinical management.

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3887
Mesenchymal stem cells in lung diseases and their potential use in COVID-19 ARDS: A systematized review
Bruna Benigna Sales Armstrong, Juan Carlos Montano Pedroso, José da Conceição Carvalho, Lydia Masako Ferreira
Clinics. 2023;78C:100237
3887
Highlights

  • None of the analized studies related serious adverse effects or toxicity to IV ASCs administration.

  • This review suggests optimism in IV ASCs for lung damage in severe COVID-19 ARDS.

  • Further studies on IV ASCs in COVID-19 are needed for standard dosage.

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3761
A new systematization of histological analysis for the diagnosis of Hirschsprung's disease
Suellen Serafini, Maria Mercês Santos, Ana Cristina Aoun Tannuri, Celso Di Loreto, Josiane de Oliveira Gonçalves, Uenis Tannuri
Clinics. 2023;78C:100198
3761
Highlights

  • Hirschsprung's disease is a congenital disorder characterized by intestinal sub-occlusion and the absence of neurons in the enteric nervous system, with involvement of varying segments of the large intestine.

  • The treatment is only surgical, for this reason the diagnosis must have a good accuracy.

  • This research demonstrates a simplified method to perform the diagnosis with 93% of accuracy.

  • The use of this method brings benefits to the patient, the pathologist, and the service.

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3669
Perianal fistulizing Crohn's disease is associated with a higher prevalence of HPV in the anorectal fistula tract. A comparative study
Lucas Rodrigues Boarini, Carlos Walter Sobrado, Giana Rabello Mota, Luisa Lina Villa, Idblan Carvalho de Albuquerque, Natalia Sousa Freitas Queiroz, Carolina Bortolozzo Graciolli Facanali, Sidney Roberto Nadal, Ivan Cecconello
Clinics. 2023;78C:100219
3669
Highlights

  • Perianal Crohn's disease is the main risk factor for anal cancer in IBD patients.

  • Perianal Crohn's disease patient has a chance of HPV 3.29 time higher than control.

  • High risk HPV is numerically twice as prevalent in perianal Crohn's disease patient.

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3661
Pesticide exposure and human health: Toxic legacy
Fulvio A. Scorza, Larissa Beltramim, Larissa M. Bombardi
Clinics. 2023;78C:100249
3661
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