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Vol. 87. Issue 4.
Pages 119-121 (April 2012)
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Vol. 87. Issue 4.
Pages 119-121 (April 2012)
Short communication
Immunohistochemical markers in the diagnosis of pigmented conjunctival lesions
Utilidad de marcadores inmunohistoquímicos para el diagnóstico de lesiones pigmentadas conjuntivales
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R.M. Bellido Muñoz
Corresponding author
rbellido78@hotmail.com

Corresponding author.
, I. Domínguez Hidalgo, J.L. García Serrano, C. López Peña
Hospital Clínico San Cecilio, Granada, Spain
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Abstract
Objective/Method

The aim of this study was to assess the importance of immunohistochemical markers in the diagnosis of pigmented conjunctival lesions. Due to the difficulty of making an exact clinical diagnosis, the suspicion of malignancy requires the removal of the lesion and performing a histopathology study in which immunohistochemical markers may help to determine the nature of the lesion.

Cases report/Discussion

A case is presented of a 25-year-old woman with a pigmented lesion in the caruncle. It appeared recently and was growing fast with increasing pigmentation. Due to a suspicion of malignancy, the total lesion was removed. The microscopic study revealed cellular alterations which suggested malignancy. However, after carrying out immunohistochemical markers the diagnosis was conjunctival compound nevus.

Keywords:
Pigmented conjunctival lesion
Immunohistochemical markers
Conjunctival nevus
Resumen
Objetivo/Método

Valorar la importancia de los marcadores inmunohistoquímicos para el diagnóstico de certeza de lesiones pigmentadas de la conjuntiva. Debido a la dificultad del diagnóstico clínico exacto, la sospecha de malignidad obliga a realizar una extirpación de la lesión y estudio anatomopatológico en el cual los marcadores inmunohistoquímicos ayudan a determinar la naturaleza de la lesión.

Caso clínico/Discusión

Mujer de 25 años que presenta una lesión pigmentada en carúncula de aparición reciente y crecimiento rápido con aumento de la pigmentación. Se sospecha malig-nidad por lo que se realiza extirpación total de la lesión. El estudio microscópico muestra alteraciones celulares sugerentes de malignidad pero tras realizar marcadores inmunohis- toquímicos el diagnóstico es nevus conjuntival compuesto.

Palabras clave:
Lesión pigmentada conjuntival
Marcadores inmunohistoquímicos
Nevus conjuntival

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