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Vol. 27. Issue 7.
Pages 408-410 (January 2004)
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Vol. 27. Issue 7.
Pages 408-410 (January 2004)
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Hepatitis crónica por virus C y enfermedad celíaca: una asociación infrecuente
Chronic hepatitis c and celiac sprue: an infrequent association
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I. Aguanchaa, J.M. Valerab, C. Hurtadob, G. Smokc, J. Brahmb,
Corresponding author
gastroen@ns.hospital.uchile.cl

Correspondencia: Dr. Javier Brahm. Hospital Clínico Universidad de Chile. Avda. Santos Dumont 999. Santiago. Chile
a Servicio de Gastroenterología. Hospital Naval Almirante Nef. Viña del Mar. Chile
b Sección de Gastroenterología. Hospital Clínico Universidad de Chile. Santiago. Chile
c Departamento de Anatomía Patológica. Hospital Clínico Universidad de Chile. Santiago. Chile
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Resumen

Se ha dicho que la enfermedad celíaca (EC) podría ser otra manifestación autoinmune asociada al virus hepatitis C (VHC). Se presentan 2 casos de pacientes con hepatitis crónica por VHC, una mujer y un varón de 42 y 59 años, respectivamente, en los que, por sintomatología diversa, se realizó una endoscopia digestiva alta con biopsias de duodeno compatibles con EC y marcadores serológicos positivos para esta enfermedad. Se discute la asociación entre ambas patologías, su base inmunológica y relación eventual con el tratamiento antiviral.

Celiac sprue (CS) has been described in association with hepatitis C virus (HCV) as another immunologic manifestation of this infectious disease.

We report 2 patients, a 42-year-old woman and a 59-yearold man, with chronic HCV hepatitis. Upper digestive endoscopy and duodenal biopsy were performed to investigate diverse symptoms. The results of histological analysis and serological study were compatible with CS. The association between both diseases, including immunological aspects and the implications of anti-HCV treatment, is discussed.

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Copyright © 2004. Elsevier España, S.L.. Todos los derechos reservados
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