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22687
Melkersson-Rosenthal syndrome – delay in the diagnosis of an early-onset oligosymptomatic variant
Fabrícia Carolino, Margarida Fernandes, José Luís Plácido
Porto Biomed J. 2016;1:43-5
22687
Open access
16209
Pulsed electromagnetic field therapy effectiveness in low back pain: A systematic review of randomized controlled trials
Renato Andrade, Hugo Duarte, Rogério Pereira, Isabel Lopes, Hélder Pereira, Rui Rocha, João Espregueira-Mendes
Porto Biomed J. 2016;1:156-63
16209
Open access
15952
The PD-1:PD-L1 immune inhibitory checkpoint in Helicobacter pylori infection and gastric cancer: a comprehensive review and future perspectives
Rui Silva, Irene Gullo, Fátima Carneiro
Porto Biomed J. 2016;1:4-11
15952
Open access
12527
Communication skills in medical students – An exploratory study before and after clerkships
Isabel Taveira-Gomes, Rui Mota-Cardoso, Margarida Figueiredo-Braga
Porto Biomed J. 2016;1:173-80
12527
Open access
11992
The impact of folic acid supplementation on gestational and long term health: Critical temporal windows, benefits and risks
Carla Silva, Elisa Keating, Elisabete Pinto
Porto Biomed J. 2017;2:315-32
11992
Highlights

  • Associations between FA supplementation in pregnancy and effects on offspring's NTDs, allergy/respiratory problems, cancer and behaviour problems as been studied.

  • There is growing concern about the effects of excessive FA supplementation, whether in terms of doses or times of exposure.

  • FA supplementation in the periconceptional period is protective against NTDs while in later periods it could be deleterious.

  • A daily dose of 0.4mg FA in the periconceptional period seems to be effective and safe.

Open access
7898
Probiotics for the control of obesity – Its effect on weight change
Ana Lídia Rouxinol-Dias, Ana Raquel Pinto, Catarina Janeiro, Daniel Rodrigues, Marta Moreira, João Dias, Pedro Pereira
Porto Biomed J. 2016;1:12-24
7898
Open access
7660
Recognition of chronic hypoxia and pre-existing foetal injury on the cardiotocograph (CTG): Urgent need to think beyond the guidelines
Susana Pereira, Edwin Chandraharan
Porto Biomed J. 2017;2:124-9
7660
Open access
7054
The importance of outdoor play for young children's healthy development
Gabriela Bento, Gisela Dias
Porto Biomed J. 2017;2:157-60
7054
Open access
6875
Cognitive and emotional impairments in obsessive–compulsive disorder: Evidence from functional brain alterations
Óscar F. Gonçalves, Sandra Carvalho, Jorge Leite, Ana Fernandes-Gonçalves, Angel Carracedo, Adriana Sampaio
Porto Biomed J. 2016;1:92-105
6875
Open access
6548
Reversible cerebral vasoconstriction syndrome – A narrative revision of the literature
Laura Santos, Elsa Azevedo
Porto Biomed J. 2016;1:65-71
6548
Open access
6381
Rituximab in generalized myasthenia gravis: Clinical, quality of life and cost–utility analysis
João Peres, Rita Martins, José Delgado Alves, Ana Valverde
Porto Biomed J. 2017;2:81-5
6381
Highlights

  • Rituximab use in MG patients lead to the reduction of relapses and to a lesser use of immunosuppressive agents in our series.

  • Rituximab use in our MG patients decreased healthcare costs after treatment, comparing to the pre-treatment period.

  • Rituximab is a clinical effective treatment for B cell-related diseases like MG and seems to be a cost–saving intervention.

Open access
6214
Regulation of colonic epithelial butyrate transport: Focus on colorectal cancer
Pedro Gonçalves, Fátima Martel
Porto Biomed J. 2016;1:83-91
6214
Highlights

  • Fermentation of the dietary fiber by intestinal microflora results in production of butyrate.

  • Butyrate possesses anticarcinogenic effect at the colonic level.

  • Three transporters (MCT1, SMCT1 and BCRP) regulate the intracellular concentration of BT in colonic epithelial cells.

  • Changes in the expression of these transporters occur in colorectal cancer.

Open access
6121
Comparison between effects of antibiotics, NSAIDs and their mixture on the growth of microorganisms
S. Bhattacharya, Y. Akula, G.M. Mitongo, Q. Khorram
Porto Biomed J. 2017;2:176-7
6121
Open access
6023
Family physicians’ opinions on and difficulties with breaking bad news
José António Ferraz Gonçalves, Carla Almeida, Joana Amorim, Rita Baltasar, Joana Batista, Yusianmar Borrero, João Pedro Fallé, Igor Faria, Manuel Henriques, Helena Maia, Teresa Fernandes, Mariana Moreira, Susana Moreira, Camila Neves, Ana Ribeiro, Ana Santos, Filipa Silva, Susana Soares, Cristina Sousa, Joana Vicente, Rita Xavier
Porto Biomed J. 2017;2:277-81
6023
Highlights

  • Breaking bad news is still deemed a difficult task by family physicians.

  • Family physicians feel they need training in breaking bad news.

  • The family physicians’ attitude to this issue is different from what they would wish if they themselves had a life-threatening disease.

Open access
5875
“Non-resolving pneumonia”: A case of cryptogenic organizing pneumonia
Pedro Pinto-Lopes, André Santos Silva, Joana Pimenta
Porto Biomed J. 2016;1:191-2
5875
Open access
5746
Statins as anti-inflammatory agents: A potential therapeutic role in sight-threatening non-infectious uveitis
Rose Gilbert, Ahmed Al-Janabi, Oren Tomkins-Netzer, Sue Lightman
Porto Biomed J. 2017;2:33-9
5746
Open access
5578
The effects of cannabinoids in exemestane-resistant breast cancer cells
C. Almeida, T. Augusto, G. Correia-da-Silva, N. Teixeira, C. Amaral
Porto Biomed J. 2017;2:221-2
5578
Open access
5266
Congenital dacryocystocele in infant: A rare cause of eye swelling
Fábio Barroso, Renato Silva, Catarina Mendes
Porto Biomed J. 2017;2:28-9
5266
Open access
5018
Topical use of probiotics: The natural balance
Freni Kekhasharú Tavaria
Porto Biomed J. 2017;2:69-70
5018
Open access
5005
Comorbidities impact on the prognosis of severe acute community-acquired pneumonia
Ana Vidal, Lurdes Santos
Porto Biomed J. 2017;2:265-72
5005
Highlights

  • Host comorbidities impact on prognosis of severe community-acquired pneumonia.

  • Association of severity indexes, clinical and analytic parameters at admission and patient comorbidities with mortality.

  • Characterization of severe community-acquired pneumonia patients admitted to ICU.

Open access
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