13333
Regulation of colonic epithelial butyrate transport: Focus on colorectal cancerPedro Gonçalves, Fátima Martel
Porto Biomed J. 2016;1:83-91
13333
Highlights
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Fermentation of the dietary fiber by intestinal microflora results in production of butyrate.
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Butyrate possesses anticarcinogenic effect at the colonic level.
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Three transporters (MCT1, SMCT1 and BCRP) regulate the intracellular concentration of BT in colonic epithelial cells.
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Changes in the expression of these transporters occur in colorectal cancer.
8813
Relevance of peroxynitrite formation and 3-nitrotyrosine on spermatozoa physiologyDaniel Filipe Cruz, Margarida Fardilha
Porto Biomed J. 2016;1:129-35
8813
Highlights
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Male fertility decline has been attributed, in part, to increased oxidative stress.
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Here we will focus on spermatozoa ROS, namely O2•−, NO and ONOO− and their contribution to protein tyrosine nitration, namely by 3-NT formation.
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An in depth review will be made on the methods used to detect protein oxidation.
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Detecting 3-NT in sperm proteins will have a crucial clinical impact, namely on the follow up of anti-oxidant therapies.
8408
Sodium intake and Helicobacter pylori infection in the early stages of lifeCatarina Monteiro, Ana Rute Costa, Bárbara Peleteiro
Porto Biomed J. 2016;1:52-8
8408
Highlights
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H. pylori was observed in 30% of children and 26% had excessive sodium intake.
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No association was found between sodium intake and H. pylori infection in early life.
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This is the first study testing sodium effect in H. pylori infection in children.
5832
Plasma cell leukaemiaCarlos Galvão Braga, Ana Raquel Rodrigues, Marina Alves, Catarina Portela, Luísa Pinto, Herlander Marques
Porto Biomed J. 2016;1:49-51
5832
5079
Indoor air quality and atopic sensitization in primary schools: A follow-up studyJoão Cavaleiro Rufo, Joana Madureira, Inês Paciência, Lívia Aguiar, João Paulo Teixeira, André Moreira, Eduardo de Oliveira Fernandes
Porto Biomed J. 2016;1:142-6
5079
Highlights
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The SINPHONIE guidelines were successful in reducing PM2.5 and PM10 in schools.
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The schools failed to reduce the levels of other IAQ pollutants.
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No significant changes were observed in the prevalence of atopy.
4981
Association between energy density and diet cost in childrenAna Patrícia Faria, Gabriela Albuquerque, Pedro Moreira, Rafaela Rosário, Ana Araújo, Vitor Teixeira, Renata Barros, Óscar Lopes, ... Patrícia Padrão
Porto Biomed J. 2016;1:106-11
4981
Highlights
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The average of the energy-adjusted diet cost in 6-12 years-old children was 2.17€/1000Kcal (SD+0.49).
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Energy-density diets (EDs - Kcal/g) were calculated by three distinct methods: (1) with food and all beverages (ED1), (2) with food and caloric beverages (ED2), and (3) only with food (ED3).
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The distributions of the three EDs were statistically different, being higher the ED3 - calculated excluding all beverages (1.15Kcal (SD+0.28) vs. ED2: 1.10Kcal/g; SD+0.24 vs. ED1: 0.99Kcal/g; SD+0.22).
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Lower energy-density diets (EDs) were associated with higher diet cost in a sample of school children from a Mediterranean country, regardless the differences between the EDs calculated by three distinct methods.
