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10941
The PD-1:PD-L1 immune inhibitory checkpoint in Helicobacter pylori infection and gastric cancer: a comprehensive review and future perspectives
Rui Silva, Irene Gullo, Fátima Carneiro
Porto Biomed J. 2016;1:4-11
10941
Open access
4959
Melkersson-Rosenthal syndrome – delay in the diagnosis of an early-onset oligosymptomatic variant
Fabrícia Carolino, Margarida Fernandes, José Luís Plácido
Porto Biomed J. 2016;1:43-5
4959
Open access
3893
Regulation of colonic epithelial butyrate transport: Focus on colorectal cancer
Pedro Gonçalves, Fátima Martel
Porto Biomed J. 2016;1:83-91
3893

  • Fermentation of the dietary fiber by intestinal microflora results in production of butyrate.

  • Butyrate possesses anticarcinogenic effect at the colonic level.

  • Three transporters (MCT1, SMCT1 and BCRP) regulate the intracellular concentration of BT in colonic epithelial cells.

  • Changes in the expression of these transporters occur in colorectal cancer.

Open access
3586
Reversible cerebral vasoconstriction syndrome – A narrative revision of the literature
Laura Santos, Elsa Azevedo
Porto Biomed J. 2016;1:65-71
3586
Open access
3351
Sodium intake and Helicobacter pylori infection in the early stages of life
Catarina Monteiro, Ana Rute Costa, Bárbara Peleteiro
Porto Biomed J. 2016;1:52-8
3351

  • H. pylori was observed in 30% of children and 26% had excessive sodium intake.

  • No association was found between sodium intake and H. pylori infection in early life.

  • This is the first study testing sodium effect in H. pylori infection in children.

Open access
3035
Pulsed electromagnetic field therapy effectiveness in low back pain: A systematic review of randomized controlled trials
Renato Andrade, Hugo Duarte, Rogério Pereira, Isabel Lopes, Hélder Pereira, Rui Rocha, João Espregueira-Mendes
Porto Biomed J. 2016;1:156-63
3035
Open access
3032
A biopsychosocial approach to the interrelation between motherhood and women's excessive weight
Ana Henriques, Ana Azevedo
Porto Biomed J. 2016;1:59-64
3032
Open access
2925
Probiotics for the control of obesity – Its effect on weight change
Ana Lídia Rouxinol-Dias, Ana Raquel Pinto, Catarina Janeiro, Daniel Rodrigues, Marta Moreira, João Dias, Pedro Pereira
Porto Biomed J. 2016;1:12-24
2925
Open access
2770
Cognitive and emotional impairments in obsessive–compulsive disorder: Evidence from functional brain alterations
Óscar F. Gonçalves, Sandra Carvalho, Jorge Leite, Ana Fernandes-Gonçalves, Angel Carracedo, Adriana Sampaio
Porto Biomed J. 2016;1:92-105
2770
Open access
2601
Kidney cancer. Heavy metals as a risk factor
Isabel Sá, Mariana Semedo, Mónica Elisabete Cunha
Porto Biomed J. 2016;1:25-8
2601
Open access
2555
Indoor air quality and atopic sensitization in primary schools: A follow-up study
João Cavaleiro Rufo, Joana Madureira, Inês Paciência, Lívia Aguiar, João Paulo Teixeira, André Moreira, Eduardo de Oliveira Fernandes
Porto Biomed J. 2016;1:142-6
2555

  • The SINPHONIE guidelines were successful in reducing PM2.5 and PM10 in schools.

  • The schools failed to reduce the levels of other IAQ pollutants.

  • No significant changes were observed in the prevalence of atopy.

Open access
2542
Relevance of peroxynitrite formation and 3-nitrotyrosine on spermatozoa physiology
Daniel Filipe Cruz, Margarida Fardilha
Porto Biomed J. 2016;1:129-35
2542

  • Male fertility decline has been attributed, in part, to increased oxidative stress.

  • Here we will focus on spermatozoa ROS, namely O2•−, NO and ONOO and their contribution to protein tyrosine nitration, namely by 3-NT formation.

  • An in depth review will be made on the methods used to detect protein oxidation.

  • Detecting 3-NT in sperm proteins will have a crucial clinical impact, namely on the follow up of anti-oxidant therapies.

Open access
2341
Cultural adaptation and validation of the Portuguese End of Life Spiritual Comfort Questionnaire in Palliative Care patients
Sara Maria Oliveira Pinto, Sílvia Maria Alves Caldeira Berenguer, José Carlos Amado Martins, Katharine Kolcaba
Porto Biomed J. 2016;1:147-52
2341
Open access
2326
Communication skills in medical students – An exploratory study before and after clerkships
Isabel Taveira-Gomes, Rui Mota-Cardoso, Margarida Figueiredo-Braga
Porto Biomed J. 2016;1:173-80
2326
Open access
2314
Parkinson's Disease and development of levodopa induced motor complications: Influence of baseline features and first medical approach
Alexandra Sofia Rua Rafael, Joselina Maria Pinto Barbosa, Maria José Silva Leão Rosas, Maria Carolina Lobo Almeida Garrett
Porto Biomed J. 2016;1:136-41
2314
Open access
1987
The acute effect of the antioxidant drug “U-74389G” on mean platelet volume levels during hypoxia reoxygenation injury in rats
C. Tsompos, C. Panoulis, K. Toutouzas, A. Triantafyllou, G. Zografos, A. Papalois
Porto Biomed J. 2016;1:186-90
1987
Open access
1973
“Non-resolving pneumonia”: A case of cryptogenic organizing pneumonia
Pedro Pinto-Lopes, André Santos Silva, Joana Pimenta
Porto Biomed J. 2016;1:191-2
1973
Open access
1870
A fatal case of upper-extremity deep vein thrombosis
Pedro Pinto-Lopes, Pedro von Hafe
Porto Biomed J. 2016;1:124-5
1870
Open access
1719
Association between energy density and diet cost in children
Ana Patrícia Faria, Gabriela Albuquerque, Pedro Moreira, Rafaela Rosário, Ana Araújo, Vitor Teixeira, Renata Barros, Óscar Lopes, André Moreira, Patrícia Padrão
Porto Biomed J. 2016;1:106-11
1719

  • The average of the energy-adjusted diet cost in 6-12 years-old children was 2.17€/1000Kcal (SD+0.49).

  • Energy-density diets (EDs - Kcal/g) were calculated by three distinct methods: (1) with food and all beverages (ED1), (2) with food and caloric beverages (ED2), and (3) only with food (ED3).

  • The distributions of the three EDs were statistically different, being higher the ED3 - calculated excluding all beverages (1.15Kcal (SD+0.28) vs. ED2: 1.10Kcal/g; SD+0.24 vs. ED1: 0.99Kcal/g; SD+0.22).

  • Lower energy-density diets (EDs) were associated with higher diet cost in a sample of school children from a Mediterranean country, regardless the differences between the EDs calculated by three distinct methods.

Open access
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