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22184
Melkersson-Rosenthal syndrome – delay in the diagnosis of an early-onset oligosymptomatic variant
Fabrícia Carolino, Margarida Fernandes, José Luís Plácido
Porto Biomed J. 2016;1:43-5
22184
Open access
15681
The PD-1:PD-L1 immune inhibitory checkpoint in Helicobacter pylori infection and gastric cancer: a comprehensive review and future perspectives
Rui Silva, Irene Gullo, Fátima Carneiro
Porto Biomed J. 2016;1:4-11
15681
Open access
15641
Pulsed electromagnetic field therapy effectiveness in low back pain: A systematic review of randomized controlled trials
Renato Andrade, Hugo Duarte, Rogério Pereira, Isabel Lopes, Hélder Pereira, Rui Rocha, João Espregueira-Mendes
Porto Biomed J. 2016;1:156-63
15641
Open access
12083
Communication skills in medical students – An exploratory study before and after clerkships
Isabel Taveira-Gomes, Rui Mota-Cardoso, Margarida Figueiredo-Braga
Porto Biomed J. 2016;1:173-80
12083
Open access
11617
The impact of folic acid supplementation on gestational and long term health: Critical temporal windows, benefits and risks
Carla Silva, Elisa Keating, Elisabete Pinto
Porto Biomed J. 2017;2:315-32
11617
Highlights

  • Associations between FA supplementation in pregnancy and effects on offspring's NTDs, allergy/respiratory problems, cancer and behaviour problems as been studied.

  • There is growing concern about the effects of excessive FA supplementation, whether in terms of doses or times of exposure.

  • FA supplementation in the periconceptional period is protective against NTDs while in later periods it could be deleterious.

  • A daily dose of 0.4mg FA in the periconceptional period seems to be effective and safe.

Open access
7481
Probiotics for the control of obesity – Its effect on weight change
Ana Lídia Rouxinol-Dias, Ana Raquel Pinto, Catarina Janeiro, Daniel Rodrigues, Marta Moreira, João Dias, Pedro Pereira
Porto Biomed J. 2016;1:12-24
7481
Open access
6696
Cognitive and emotional impairments in obsessive–compulsive disorder: Evidence from functional brain alterations
Óscar F. Gonçalves, Sandra Carvalho, Jorge Leite, Ana Fernandes-Gonçalves, Angel Carracedo, Adriana Sampaio
Porto Biomed J. 2016;1:92-105
6696
Open access
6565
The importance of outdoor play for young children's healthy development
Gabriela Bento, Gisela Dias
Porto Biomed J. 2017;2:157-60
6565
Open access
6341
Reversible cerebral vasoconstriction syndrome – A narrative revision of the literature
Laura Santos, Elsa Azevedo
Porto Biomed J. 2016;1:65-71
6341
Open access
6042
Regulation of colonic epithelial butyrate transport: Focus on colorectal cancer
Pedro Gonçalves, Fátima Martel
Porto Biomed J. 2016;1:83-91
6042
Highlights

  • Fermentation of the dietary fiber by intestinal microflora results in production of butyrate.

  • Butyrate possesses anticarcinogenic effect at the colonic level.

  • Three transporters (MCT1, SMCT1 and BCRP) regulate the intracellular concentration of BT in colonic epithelial cells.

  • Changes in the expression of these transporters occur in colorectal cancer.

Open access
6012
Rituximab in generalized myasthenia gravis: Clinical, quality of life and cost–utility analysis
João Peres, Rita Martins, José Delgado Alves, Ana Valverde
Porto Biomed J. 2017;2:81-5
6012
Highlights

  • Rituximab use in MG patients lead to the reduction of relapses and to a lesser use of immunosuppressive agents in our series.

  • Rituximab use in our MG patients decreased healthcare costs after treatment, comparing to the pre-treatment period.

  • Rituximab is a clinical effective treatment for B cell-related diseases like MG and seems to be a cost–saving intervention.

Open access
5818
Family physicians’ opinions on and difficulties with breaking bad news
José António Ferraz Gonçalves, Carla Almeida, Joana Amorim, Rita Baltasar, Joana Batista, Yusianmar Borrero, João Pedro Fallé, Igor Faria, Manuel Henriques, Helena Maia, Teresa Fernandes, Mariana Moreira, Susana Moreira, Camila Neves, Ana Ribeiro, Ana Santos, Filipa Silva, Susana Soares, Cristina Sousa, Joana Vicente, Rita Xavier
Porto Biomed J. 2017;2:277-81
5818
Highlights

  • Breaking bad news is still deemed a difficult task by family physicians.

  • Family physicians feel they need training in breaking bad news.

  • The family physicians’ attitude to this issue is different from what they would wish if they themselves had a life-threatening disease.

Open access
5631
“Non-resolving pneumonia”: A case of cryptogenic organizing pneumonia
Pedro Pinto-Lopes, André Santos Silva, Joana Pimenta
Porto Biomed J. 2016;1:191-2
5631
Open access
5585
Comparison between effects of antibiotics, NSAIDs and their mixture on the growth of microorganisms
S. Bhattacharya, Y. Akula, G.M. Mitongo, Q. Khorram
Porto Biomed J. 2017;2:176-7
5585
Open access
5571
Statins as anti-inflammatory agents: A potential therapeutic role in sight-threatening non-infectious uveitis
Rose Gilbert, Ahmed Al-Janabi, Oren Tomkins-Netzer, Sue Lightman
Porto Biomed J. 2017;2:33-9
5571
Open access
5372
The effects of cannabinoids in exemestane-resistant breast cancer cells
C. Almeida, T. Augusto, G. Correia-da-Silva, N. Teixeira, C. Amaral
Porto Biomed J. 2017;2:221-2
5372
Open access
5038
Congenital dacryocystocele in infant: A rare cause of eye swelling
Fábio Barroso, Renato Silva, Catarina Mendes
Porto Biomed J. 2017;2:28-9
5038
Open access
4880
Comorbidities impact on the prognosis of severe acute community-acquired pneumonia
Ana Vidal, Lurdes Santos
Porto Biomed J. 2017;2:265-72
4880
Highlights

  • Host comorbidities impact on prognosis of severe community-acquired pneumonia.

  • Association of severity indexes, clinical and analytic parameters at admission and patient comorbidities with mortality.

  • Characterization of severe community-acquired pneumonia patients admitted to ICU.

Open access
4857
Topical use of probiotics: The natural balance
Freni Kekhasharú Tavaria
Porto Biomed J. 2017;2:69-70
4857
Open access
es en pt

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