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37805
Melkersson-Rosenthal syndrome – delay in the diagnosis of an early-onset oligosymptomatic variant
Fabrícia Carolino, Margarida Fernandes, José Luís Plácido
Porto Biomed J. 2016;1:43-5
37805
Open access
29261
Pulsed electromagnetic field therapy effectiveness in low back pain: A systematic review of randomized controlled trials
Renato Andrade, Hugo Duarte, Rogério Pereira, Isabel Lopes, Hélder Pereira, Rui Rocha, João Espregueira-Mendes
Porto Biomed J. 2016;1:156-63
29261
Open access
22296
The impact of folic acid supplementation on gestational and long term health: Critical temporal windows, benefits and risks
Carla Silva, Elisa Keating, Elisabete Pinto
Porto Biomed J. 2017;2:315-32
22296
Highlights

  • Associations between FA supplementation in pregnancy and effects on offspring's NTDs, allergy/respiratory problems, cancer and behaviour problems as been studied.

  • There is growing concern about the effects of excessive FA supplementation, whether in terms of doses or times of exposure.

  • FA supplementation in the periconceptional period is protective against NTDs while in later periods it could be deleterious.

  • A daily dose of 0.4mg FA in the periconceptional period seems to be effective and safe.

Open access
20215
Comparison between effects of antibiotics, NSAIDs and their mixture on the growth of microorganisms
S. Bhattacharya, Y. Akula, G.M. Mitongo, Q. Khorram
Porto Biomed J. 2017;2:176-7
20215
Open access
19978
Communication skills in medical students – An exploratory study before and after clerkships
Isabel Taveira-Gomes, Rui Mota-Cardoso, Margarida Figueiredo-Braga
Porto Biomed J. 2016;1:173-80
19978
Open access
18846
The PD-1:PD-L1 immune inhibitory checkpoint in Helicobacter pylori infection and gastric cancer: a comprehensive review and future perspectives
Rui Silva, Irene Gullo, Fátima Carneiro
Porto Biomed J. 2016;1:4-11
18846
Open access
15132
Rituximab in generalized myasthenia gravis: Clinical, quality of life and cost–utility analysis
João Peres, Rita Martins, José Delgado Alves, Ana Valverde
Porto Biomed J. 2017;2:81-5
15132
Highlights

  • Rituximab use in MG patients lead to the reduction of relapses and to a lesser use of immunosuppressive agents in our series.

  • Rituximab use in our MG patients decreased healthcare costs after treatment, comparing to the pre-treatment period.

  • Rituximab is a clinical effective treatment for B cell-related diseases like MG and seems to be a cost–saving intervention.

Open access
13047
Recognition of chronic hypoxia and pre-existing foetal injury on the cardiotocograph (CTG): Urgent need to think beyond the guidelines
Susana Pereira, Edwin Chandraharan
Porto Biomed J. 2017;2:124-9
13047
Open access
12818
Role of platelets in immune system and inflammation
Ozge Sonmez, Mehmet Sonmez
Porto Biomed J. 2017;2:311-4
12818
Open access
12422
The importance of outdoor play for young children's healthy development
Gabriela Bento, Gisela Dias
Porto Biomed J. 2017;2:157-60
12422
Open access
11380
Cognitive and emotional impairments in obsessive–compulsive disorder: Evidence from functional brain alterations
Óscar F. Gonçalves, Sandra Carvalho, Jorge Leite, Ana Fernandes-Gonçalves, Angel Carracedo, Adriana Sampaio
Porto Biomed J. 2016;1:92-105
11380
Open access
10779
Botulinum toxin improves pain in chronic anal fissure
Hugo Amorim, José Santoalha, Rui Cadilha, Maria-José Festas, Paula Barbosa, Armanda Gomes
Porto Biomed J. 2017;2:273-6
10779
Highlights

  • Chronic anal fissure is a common condition associated with intense pain.

  • Local botulinum toxin injection is a valid option in its management.

  • Pain intensity scores significantly improved after BoNT injection.

  • Side effects were rare and mild.

  • Our results support the inclusion of BoNT in the management algorithm of chronic anal fissure.

Open access
9687
Probiotics for the control of obesity – Its effect on weight change
Ana Lídia Rouxinol-Dias, Ana Raquel Pinto, Catarina Janeiro, Daniel Rodrigues, Marta Moreira, João Dias, Pedro Pereira
Porto Biomed J. 2016;1:12-24
9687
Open access
8932
Congenital dacryocystocele in infant: A rare cause of eye swelling
Fábio Barroso, Renato Silva, Catarina Mendes
Porto Biomed J. 2017;2:28-9
8932
Open access
8543
Regulation of colonic epithelial butyrate transport: Focus on colorectal cancer
Pedro Gonçalves, Fátima Martel
Porto Biomed J. 2016;1:83-91
8543
Highlights

  • Fermentation of the dietary fiber by intestinal microflora results in production of butyrate.

  • Butyrate possesses anticarcinogenic effect at the colonic level.

  • Three transporters (MCT1, SMCT1 and BCRP) regulate the intracellular concentration of BT in colonic epithelial cells.

  • Changes in the expression of these transporters occur in colorectal cancer.

Open access
8170
Reversible cerebral vasoconstriction syndrome – A narrative revision of the literature
Laura Santos, Elsa Azevedo
Porto Biomed J. 2016;1:65-71
8170
Open access
7924
Family physicians’ opinions on and difficulties with breaking bad news
José António Ferraz Gonçalves, Carla Almeida, Joana Amorim, Rita Baltasar, Joana Batista, Yusianmar Borrero, João Pedro Fallé, Igor Faria, ... Rita Xavier
Porto Biomed J. 2017;2:277-81
7924
Highlights

  • Breaking bad news is still deemed a difficult task by family physicians.

  • Family physicians feel they need training in breaking bad news.

  • The family physicians’ attitude to this issue is different from what they would wish if they themselves had a life-threatening disease.

Open access
7814
“Non-resolving pneumonia”: A case of cryptogenic organizing pneumonia
Pedro Pinto-Lopes, André Santos Silva, Joana Pimenta
Porto Biomed J. 2016;1:191-2
7814
Open access
7703
Public and patient participation in health policy, care and research
Cláudia de Freitas
Porto Biomed J. 2017;2:31-2
7703
Open access
7577
Topical use of probiotics: The natural balance
Freni Kekhasharú Tavaria
Porto Biomed J. 2017;2:69-70
7577
Open access
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos