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Annals of Hepatology
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Special Issue on Genomic Medicine in Obesity and Chronic Liver Damage

Edited by Sonia Roman

Obesity is a complex disease comprising multiple genetic and environmental factors causing important metabolic dysfunctionalities in body organs including the liver. Currently, the aim is to provide personalized medicine and nutrition strategies to detect, manage and treat obesity-related liver damage at earlier stages and avoid end-stage liver disease. Basic and clinical research are needed to guide and reinforce the capacities of regional health care systems to respond according to the biological characteristics of the population.

Based on the Aim and Scope of Annals of Hepatology, we enthusiastically announce our Special Issue "Obesity and Liver Damage" for authors to contribute with original articles and reviews. We welcome studies focusing on strategies for early detection, prevention, medical or nutritional therapies using "omics" methodologies either accessed exclusively or in combination with lifestyle factors (diet, physical activity, mental health). Large cohort prospective/retrospective epidemiological studies could be considered. We hope that these contributions aid in increasing our insights on the prevention of obesity and chronic liver damage in populations of Latin America and other regions around the world.
Genomic medicine in hepatology: Towards personalized medicine in obesity and chronic liver disease
Sonia Roman, Omar Ramos-Lopez, Arturo Panduro
Ann Hepatol. 2023;28:100875
Open access
NAFLD VS MAFLD. The evidence-based debate has come. Time to change?
Diego García-Compeán, Alan Rafael Jiménez-Rodríguez
Ann Hepatol. 2022;27:100765
Full text access
Non-alcoholic fatty liver disease prevalence in Latin America: A systematic review and meta-analysis
Yesmi A. Ortega Rojas, Claudia L. Vidal Cuellar, Karina M. Aparicio Barrón, Juan Pablo Arab, Adelina Lozano Miranda
Ann Hepatol. 2022;27:100706
Full text access
Activation of the NLRP3 inflammasome by CCl4 exacerbates hepatopathogenic diet-induced experimental NASH
Eduardo E. Vargas-Pozada, Erika Ramos-Tovar, Juan D. Rodriguez-Callejas, Irina Cardoso-Lezama, Silvia Galindo-Gómez, Karla Gil-Becerril, Verónica Rocío Vásquez-Garzón, Jaime Arellanes-Robledo, ... Pablo Muriel
Ann Hepatol. 2023;28:100780
Open access
African genetic ancestry is associated with lower frequency of PNPLA3 G allele in non-alcoholic fatty liver in an admixed population
Lourianne Nascimento Cavalcante, Jun Porto, Daniel Mazo, Adhemar Longatto-Filho, José Tadeu Stefano, Andre Castro Lyra, Flair Jose Carrilho, Rui Manuel Reis, ... Claudia P Oliveira
Ann Hepatol. 2022;27:100728
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Whole-Exome Sequencing identified Olfactory Receptor genes as a key contributor to extreme obesity with progression to nonalcoholic steatohepatitis in Mexican patients
Luis Alberto Torres-Reyes, Karina Gonzalez-Aldaco, Arturo Panduro, Alexis Jose-Abrego, Sonia Roman
Ann Hepatol. 2022;27:100767
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Abdominal obesity, chronic inflammation and the risk of non-alcoholic fatty liver disease
Dongna Zhao, Haozhe Cui, Zhiqiang Shao, Liying Cao
Ann Hepatol. 2023;28:100726
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Diagnostic accuracy of blood biomarkers and non-invasive scores for the diagnosis of NAFLD and NASH: Systematic review and meta-analysis
Daniela Contreras, Alejandra González-Rocha, Patricia Clark, Simón Barquera, Edgar Denova-Gutiérrez
Ann Hepatol. 2023;28:100873
Open access
What do we know about nutrient-based strategies targeting molecular mechanisms associated with obesity-related fatty liver disease?
Ingrid Rivera-Iñiguez, Arturo Panduro, Sonia Roman, Karina González-Aldaco
Ann Hepatol. 2023;28:100874
Open access
Body weight loss and glycemic control on the outcomes of patients with NAFLD. The role of new antidiabetic agents
Diego García-Compeán, Ramesh Kumar, Ángel Noe del Cueto-Aguilera, Héctor Jesús Maldonado-Garza, Jesús Zacarías Villarreal-Pérez
Ann Hepatol. 2023;28:100751
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Anti-hepatitis B virus activity of food nutrients and potential mechanisms of action
Alexis Jose-Abrego, Ingrid Rivera-Iñiguez, Luis A. Torres-Reyes, Sonia Roman
Ann Hepatol. 2023;28:100766
Full text access
Late evening snack and oral amino acid capsules improved respiratory quotient and Fischer ratio in patients with alcoholic liver cirrhosis
Juan Zhao, Jing Wu, Juan Li, Zhong-Ying Wang, Qing-Hua Meng
Ann Hepatol. 2023;28:100750
Full text access
Body mass index implications in intrahepatic cholestasis of pregnancy and placental histopathological alterations
Violeta Valdovinos-Bello, Carmen Selene García-Romero, Alicia Cervantes-Peredo, Elizabeth García-Gómez, Alejandra Martínez-Ibarra, Edgar Ricardo Vázquez-Martínez, Yolotzin Valdespino, Marco Cerbón
Ann Hepatol. 2023;28:100879
Open access
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