Acidosis láctica y metformina: a propósito de tres casos
Lactic acidosis and metformin: based on 3 cases
Metformin is a biguanide used in the treatment of obese adults with type 2 diabetes mellitus. In this group of patients, metformin substantially decreases mortality in comparison with other conventional treatments. However, if acute renal failure occurs for any reason, metformin may accumulate in the body and cause lactic acidosis. We report three cases of diabetic patients who receiving metformin for the treatment of diabetes experienced acute renal failure. As a consequence of this, they developed lactic acidosis with increased gap anion that required admission to ours Intensive Care Units.
metformina, acidosis láctica
metformin, lactic acidosis