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Endocrinol Nutr 2002;49:202-6 - DOI: 10.1016/S1575-0922(02)74456-2
Evolución de tumores hipofisarios en miembros de una familia con síndrome de neoplasia endocrina múltiple tipo 1
Different outcome of pituitary tumors within members of a family with multiple endocrine neoplasia type 1
C. Alonso Rodríguez, A. Lisbona Gil, S. Sancha Canales
Servicios de Endocrinología y de Hospital Militar Central Gómez Ulla. Madrid
F. Esteban Alonsoa
a Servicios de Endocrinología y de Radiología. Hospital Militar Central Gómez Ulla. Madrid
Recibido 08 octubre 2001, Aceptado 11 marzo 2002
Resumen

The outcome of prolactinoma in two members of the same family with multiple endocrine neoplasia type 1 is reported. Early diagnosis was made in two brothers aged 21 and 14 years old by hormonal and genetic screening and was confirmed by nuclear magnetic resonance of the pituitary. Plasma prolactin levels returned to normal in both patients in response to treatment with dopamine agonists. However, while in one patient the tumoral mass disappeared completely, in the other, the tumor continued to grow and required transphenoidal surgery.

Palabras clave
Neoplasia endocrina múltiple tipo 1, Tumor hipofisario, Prolactina, Prolactinoma, Agonistas dopaminérgicos, Cabergolina
Key words
Multiple Endocrine Neoplasia type 1, Pituitary tumor, Prolactimoma, Dopamine agonists, Cabergoline
El Texto completo solo está disponible en PDF
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Correspondencia: Dr. César Alonso. Servicio de Endocrinología. Hospital Militar Central Gómez Ulla. Glorieta del Ejército, s/n. 28047 Madrid. (C. Alonso Rodríguez )
Copyright © 2002. Sociedad Española de Endocrinología y Nutrición