metricas
covid
Buscar en
Gastroenterología y Hepatología (English Edition)
Toda la web
Inicio Gastroenterología y Hepatología (English Edition) A case report of drug-induced ischemic colitis accompanied by ulcerative colitis
Journal Information
Vol. 44. Issue 2.
Pages 137-138 (February 2021)
Share
Share
Download PDF
More article options
Vol. 44. Issue 2.
Pages 137-138 (February 2021)
Image of the month
Full text access
A case report of drug-induced ischemic colitis accompanied by ulcerative colitis
Un informe sobre un caso de colitis isquémica inducida por drogas acompañada de colitis ulcerosa
Visits
420
Guanyu Zhoua, Fei Xionga, Xudan Yangb, Pu Wanga,
Corresponding author
wangpuhuaxi@qq.com

Corresponding author.
a Department of Gastroenterology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China
b Department of Pathology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China
This item has received
Article information
Full Text
Bibliography
Download PDF
Statistics
Figures (1)
Full Text

A 23-year old woman, presented with progressive abdominal pain and diarrhea for 6 months. During the time, she was treated with a decocted Chinese herbal medicine for 1 month.

On colonoscopy, diffusive black spots from cecum to the sigmoid colon were found (Fig. 1A, white light). The micro-vessels around the black spots were dilated and interrupted (Fig. 1B, magnified NBI).

Figure 1
(0.74MB).

Focal crypt abscess, chronic hemorrhagic necrosis, hemosiderin and phagocytes were seen in epithelium. Inflammatory cell infiltrated into the lamina propria, dominated by lymphocytes and plasma cells. Vascular obstruction and remote hemorrhage could be seen (Fig. 1 C, as described in this paragraph).

This patient was diagnosed as drug-induced ischemic colitis1 accompanied with ulcerative colitis (UC).

The herbal medicine was discontinued. UC was treated with mesalazine. The abdominal pain and bloody diarrhea were alleviated.

Surveillance colonoscopy 3 months later showed a basically normal mucosa with rare black spots (Fig. 1D, images from surveillance colonoscopy). Pathological examination showed fewer focal crypt abscess and vasculitis, as well as a decline of lymphocyte (Fig. 1E, pathological results after treatment).

Funding

All authors declare no funding on this work.

Conflict of interest

All authors declare no conflict of interest.

Reference
[1]
C.M. Fenoglio-Preiser, A.E. Noffsinger, G.N. Stemmermann, P.E. Lantz, P.G. Isaacson.
Gastrointestinal pathology: an atlas and text.
Lippincott Williams & Wilkins, (2007), 9780781771467,
Copyright © 2020. Elsevier España, S.L.U.. All rights reserved
Download PDF
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos