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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Measures to prevent the risks associated with exposure to cytostatic drugs in gl...
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Vol. 95. Issue 7.
Pages 334-344 (July 2020)
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Vol. 95. Issue 7.
Pages 334-344 (July 2020)
Review
Measures to prevent the risks associated with exposure to cytostatic drugs in glaucoma filtering surgery
Medidas para prevenir los riesgos asociados con la exposición a citostáticos en cirugía filtrante de glaucoma
A. González-Ventosaa,
Corresponding author
aglez89@gmail.com

Corresponding author.
, J. Ariz-Juanb, N. Sabater-Cruza,c
a Institut Clínic d’Oftalmologia, ICOF, Hospital Clínic de Barcelona, Spain
b Servicio de Medicina del Trabajo, Salud Laboral y Prevención de Riesgos Laborales, Hospital Clínic de Barcelona, Spain
c Institut Oftalmològic Integral. Grup Admiravisión, Barcelona, Spain
Article information
Abstract
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Bibliography
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Figures (7)
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Tables (3)
Table 1. Effects of various hazardous drugs on animals, and results of the Ames test application collected by Vaughn and Christensen.
Table 2. Individual protection equipment to recommended for use during the specific stages of cytostatics manipulation.
Table 3. Types of biological safety booths (1).
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Abstract
Introduction

The use of cytostatic drugs such as Mitomycin C and 5-Fluorouracil is well-known in glaucoma filtering surgery, as well as the management of its complications. However, there is a lack of information regarding the preventive measures to be taken by the professional that handles these types of substances.

Objective

Raise awareness among professionals of the risks associated with the use of cytostatic drugs without adequate prevention measures.

Results

Review of the available literature and legislation on preventive measures in the management of cytostatic drugs in the medical and ophthalmological field.

Conclusions

The prevention and awareness of the risks of the qualified professionals that handle these substances is the most important measure to prevent the possible risks. Coordination is necessary with the Occupational Health teams of the Hospital, as well as the professionals and staff involved in the different phases of the process, from the preparation in Hospital Pharmacy to its elimination.

Keywords:
Glaucoma
Cytostatics
Anti-metabolites
Filtering surgery
Prevention
Occupational risks
Preventive measures
Resumen
Introducción

El uso de medicamentos citostáticos como la mitomicina C y el 5-fluorouracilo es bien conocido en cirugía filtrante de glaucoma y en el manejo de sus complicaciones, no obstante, existe una falta de información en cuanto a las medidas preventivas a tomar por parte del profesional que maneja este tipo de sustancias.

Objetivo

Concienciar al profesional sobre los riesgos asociados con el uso de medicamentos citostáticos sin la adecuada prevención.

Resultados

Revisión de la bibliografía y legislación disponible sobre medidas preventivas en el manejo de citostáticos en el ámbito médico y oftalmológico.

Conclusiones

La prevención y concienciación del profesional cualificado que maneja estas sustancias es la medida más importante para prevenir los posibles riesgos derivados. Es necesaria la coordinación con los equipos de Salud Laboral del Hospital y los profesionales y personal implicados en las distintas fases del proceso, desde la preparación en Farmacia Hospitalaria hasta su eliminación.

Palabras clave:
Glaucoma
Citostáticos
Antimetabolitos
Cirugía filtrante
Prevención
Riesgos laborales
Medidas preventivas

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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

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