Radionecrosis versus disease progression in brain metastasis. Value of 18F-DOPA PET/CT/MR

Hernández Pinzón, J.; Mena, D.; Aguilar, M.; Biafore, F.; Recondo, G.; Bastianello, M.

doi:10.1016/j.remnie.2016.06.001

Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)

ISSN: 2253-8089

The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging.
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Vol. 35. Issue 5.

Pages 332-335 (September - October 2016)

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Vol. 35. Issue 5.

Pages 332-335 (September - October 2016)

Clinical note

DOI: 10.1016/j.remnie.2016.06.001

Radionecrosis versus disease progression in brain metastasis. Value of 18F-DOPA PET/CT/MR

Radionecrosis versus progresión de la enfermedad en metástasis cerebrales: valor del 18F-DOPA PET/TC/RM

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J. Hernández Pinzóna, D. Menab, M. Aguilarc, F. Biafored, G. Recondoe, M. Bastianellob,

Corresponding author

maria.bastianello@hotmail.com

Corresponding author.

a Departamento de Imágenes, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina

b Departamento de Imágenes-Sección Imágenes Moleculares y Terapias Metabólicas, Centro de Educación Medica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina

c Departamento de Imágenes-Sección de Neurorradiología, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina

d Escuela de Ciencia y Tecnología, Universidad Nacional de San Martín, Buenos Aires, Argentina

e Departamento de Oncología, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina

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Table 1. Values of the uptake of the lesions.

Abstract

The use of 18F-DOPA PET/CT with magnetic resonance imaging fusion and the use of visual methods and quantitative analysis helps to differentiate between changes post-radiosurgery versus suspicion of disease progression in a patient with brain metastases from melanoma, thus facilitating taking early surgical action.

Keywords:

Metastasis

Melanoma

Radiation necrosis

18F-DOPA

Positron emission tomography

Magnetic resonance imaging

Resumen

La utilización del 18F-DOPA PET/TC junto a la superposición con imágenes de resonancia magnética y el empleo de métodos de análisis visual y semicuantitativo permitió diferenciar entre las alteraciones posradiocirugía vs. sospecha de progresión de la enfermedad en un paciente con metástasis cerebrales de melanoma, permitiendo tomar una conducta quirúrgica correcta precozmente.

Palabras clave:

Metástasis

Melanoma

Radionecrosis

18F-DOPA

Tomografía por Emisión de Positrones

Resonancia magnética

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