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Cirugía Española (English Edition) Study of morphological changes observed on abdominal CT scan after preoperative ...
Journal Information
Vol. 103. Issue 7.
(July 2025)
Original article
Study of morphological changes observed on abdominal CT scan after preoperative treatment with botulinum toxin type A in patients with midline incisional hernias or lateral component
Estudio de los cambios morfológicos observados en TC de abdomen en el tratamiento pre operatorio con toxina botulínica tipo A en pacientes con hernias incisionales localizadas en línea media o con componente lateral
Salvador Argudo Garijoa,
Corresponding author
, Félix Javier Jiménez Jiménezb, Jessie Ramírez Calderónc, Ariel Christian Jullien Petrellia, Javier Del Corral Rodrígueza, Miguel Hernández Garcíaa, María García-Conde Delgadoa, Alfredo Alonso Pozaa
a Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario del Sureste, Madrid, Spain
b Servicio de Neurología, Hospital Universitario del Sureste, Madrid, Spain
c Servicio de Radiodiagnóstico, Hospital Universitario del Sureste, Madrid, Spain
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Tables (6)
Table 1. Demographic characteristics of patients included in the study, percentage of recurrent hernias, and surgical origin of the incisional hernia.
Tables
Table 2. Hernia characteristics of the patients included in the study, including the maximum transverse diameter of the hernia defect and initial surgery in patients with incisional hernia and a lateral component (ML: midline laparotomy).
Tables
Table 3. Abdominal CT measurements (cm) of the overall series of patients prior to BT treatment (baseline), after BT treatment, and the comparative difference between the 2.
Tables
Table 4. Abdominal CT measurements (cm) of the group of patients with hernias located only on the midline prior to BT treatment (baseline) and after BT treatment, and the comparative difference between the 2.
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Table 5. Logistic regression analysis of the incisional hernia in a midline location as a prognostic factor for a major increase in the length of the right lateral abdominal wall after treatment with BT.
Tables
Table 6. Logistic regression analysis of the incisional hernia in a midline location as a prognostic factor for a greater increase in the transverse abdominal diameter after treatment with BT.
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Abstract
Introduction

Preoperative treatment with botulinum toxin (BT) is very common in complex incisional hernias, although it lacks clear indications.

Methods

Between July 2019 and May 2022, measurements of the thickness and length of the lateral abdominal wall, transverse diameter of the abdomen and diameter of the hernia defect were taken from patient CT scans both pre- and post-treatment with BT at our hospital. In order to establish differences between patients with lateral and midline hernias, a logistic regression analysis was performed.

Results

The study included 23 patients: 17 had midline hernias, and 6 had lateral hernias (4 right and 2 bilateral). We observed increased length of the right wall (1.15 ± 1.64 cm; P = .0029), left wall (1.96 ± 1.74 cm; P < .0001) and transverse abdominal diameter (2.85 ± 4.83 cm; P < .0001), and a reduction in the thickness of the right (−0.54 ± 0.53 cm; P < .0001) and left walls (−0.58 ± 0.42 cm; P < .0001). There were no differences in the transverse diameter of the defect (−0.01 ± 1.37 cm; P = .4593). After logistic regression, increased right wall length (OR 14.99; 95%CI 1.58–142.12) and transverse abdominal diameter (OR 9.33; 95%CI 1.13–76.68) was more likely to be observed in patients with midline hernias than in those with lateral locations.

Conclusions

Preoperative treatment with BT appears to be more effective in patients with midline hernias than in those with lateral locations.

Keywords:
Ventral hernia
Incisional hernia
Lateral incisional hernia
Botulinum toxin type A
Prehabilitation
Abbreviations:
CT
BT
HSV
ACV
Resumen
Introducción

El tratamiento pre operatorio con TB es un recurso frecuente en la cirugía de hernia incisional compleja, aunque carece de indicaciones claras.

Métodos

Entre julio 2019 y mayo 2022, se midió en nuestro centro el grosor y la longitud de la pared lateral del abdomen, el diámetro transverso del abdomen y del defecto herniario en TC realizado a pacientes pre y post tratamiento con TB. Para establecer diferencias entre pacientes con hernia lateral y de línea media se realizó una regresión logística.

Resultados

Se incluyeron 23 pacientes: 17 presentaban hernia de línea media y 6 hernia lateral (4 derechas y 2 bilaterales). Se observó un incremento de la longitud de la pared derecha (1,15 ± 1,64 cm, p = 0,0029), pared izquierda (1,96 ± 1,74 cm, p < 0,0001) y diámetro transverso del abdomen (2,85 ± 4,83 cm, p < 0,0001), y una reducción del grosor de la pared derecha (−0,54 ± 0,53 cm, p < 0,0001) e izquierda (−0,58 ± 0,42 cm, p < 0,0001). No hubo diferencias en el diámetro transverso del defecto (−0,01 ± 1,37 cm, p = 0,4593). Tras la regresión logística, es más probable observar un aumento de longitud de la pared derecha (OR 14,99, IC 95% 1,58–142,12) y del diámetro transverso del abdomen (OR 9,33 IC 95% 1,13–76,68) en los pacientes con hernias de línea media que en los de localización lateral.

Conclusiones

El tratamiento pre operatorio con TB parece ser más eficaz en pacientes con hernias de línea media que en los que presentan componente lateral.

Palabras clave:
Hernia ventral
Hernia incisional
Hernia incisional lateral
Toxina botulínica tipo A
Prehabilitación
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