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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Primary squamous cell carcinoma of the thyroid. Initial assessment and follow-up...
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Vol. 36. Issue 4.
Pages 257-259 (July - August 2017)
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Vol. 36. Issue 4.
Pages 257-259 (July - August 2017)
Clinical note
Primary squamous cell carcinoma of the thyroid. Initial assessment and follow-up using 18F-FDG PET/CT
Carcinoma epidermoide primario de tiroides. Valoración inicial y control evolutivo mediante 18F-FDG PET/TC
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L. Caballero Gullóna,
Corresponding author
, E. Carmona Gonzálezb, A. Martínez Estéveza, M.P. Gómez Camareroa, J.J. Corralc, I. Borrego Doradoa
a Servicio de Medicina Nuclear, Hospital Virgen del Rocío, Sevilla, Spain
b Servicio de Radiología, Hospital La Merced, Osuna (Sevilla), Spain
c Servicio de Oncología, Hospital Virgen del Rocío, Sevilla, Spain
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Abstract

Squamous cell carcinoma of thyroid is an uncommon, very aggressive, neoplasm, having a poor prognosis and poor response to chemotherapy and radiotherapy. Surgery is the initial treatment of choice, although it often presents as a widespread disease at the time of diagnosis, usually with cervical swelling that causes most of the symptoms due to local infiltration or metastases. Local infiltration from adjacent tumor and metastatic disease needs to be excluded from other primary epidermoid carcinomas, in order to make a correct diagnosis. This also requires the typical cytokeratin pattern seen in histological studies. The case is presented of a 53 year-old man with a medical history of hepatocarcinoma, with a cervical hypermetabolic lesion detected in an 18F-FDG PET/CT performed to exclude widespread disease. The follow-up of this lesion with this technique and its usefulness is also described.

Keywords:
Thyroid
Squamous cell carcinoma
18FDG-PET/CT
Positron emission tomography
Resumen

El carcinoma epidermoide primario de tiroides es una neoplasia muy poco frecuente, con comportamiento agresivo, de mal pronóstico, con pobre respuesta al tratamiento quimioterápico y radioterápico, y cuyo tratamiento de elección es la cirugía. Suele presentarse al diagnóstico como enfermedad extendida, como una tumefacción cervical que causa la mayoría de sus síntomas por invasión o metástasis locales. Su diagnóstico requiere excluir infiltración desde un tumor adyacente, afectación metastásica a distancia desde otro carcinoma epidermoide primario y realizar estudio inmunohistoquímico, el cual refleje el patrón característico de expresión de citoqueratinas. Presentamos el caso de un paciente de 53 años con antecedentes oncológicos de hepatocarcinoma, en el que durante el seguimiento se detecta una lesión cervical, caracterizada como hipermetabólica al realizar el estudio de extensión mediante tomografía por emisión de positrones con 18F-FDG (18F-FDG PET/TC). También presentamos el control evolutivo de dicha lesión mediante esta técnica y la utilidad de esta última.

Palabras clave:
Tiroides
Carcinoma de células escamosas
PET/TC-18FDG
Tomografía por emisión de positrones

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