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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) PET/CT in giant cell arteritis: High 18F-FDG uptake in the temporal, occipital a...
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Vol. 35. Issue 6.
Pages 398-401 (November - December 2016)
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Vol. 35. Issue 6.
Pages 398-401 (November - December 2016)
Clinical note
DOI: 10.1016/j.remnie.2016.03.008
PET/CT in giant cell arteritis: High 18F-FDG uptake in the temporal, occipital and vertebral arteries
PET/TC en la arteritis de células gigantes: alta acumulación de 18F-FDG en las arterias temporal, occipital y vertebral
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Z. Rehaka,b,c, J. Vasinaa,d, J. Ptaceke, T. Kazdaf, Z. Fojtikg, P. Nemech,
Corresponding author
petr.nemec@fnusa.cz

Corresponding author.
a Department of Nuclear Medicine and PET Center, Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic
b Regional Center for Applied Molecular Oncology (RECAMO), Masaryk Memorial Cancer Institute, Brno, Czech Republic
c Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic
d Center of Molecular Imaging, International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, Czech Republic
e Department of Nuclear Medicine and Department of Medical Physics and Radiation Protection, University Hospital, Olomouc, Czech Republic
f Department of Radiation Oncology, Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic
g Rheumatology Unit, Department of Internal Medicine – Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
h Rheumatology Unit, 2nd Department of Internal Medicine, St. Anne's University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
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Table 1. Patients and imaging characteristics of presented cases. ESR: erythrocyte sedimentation rate, CRP: C-reactive protein.
Abstract

18F-FDG PET/CT imaging is useful in patients with fever of unknown origin and can detect giant cell arteritis in extracranial large arteries. However, it is usually assumed that temporal arteries cannot be visualized with a PET/CT scanner due to their small diameter. Three patients with clinical symptoms of temporal arteritis were examined using a standard whole body PET/CT protocol (skull base – mid thighs) followed by a head PET/CT scan using the brain protocol. High 18F-FDG uptake in the aorta and some arterial branches were detected in all 3 patients with the whole body protocol. Using the brain protocol, head imaging led to detection of high 18F-FDG uptake in temporal arteries as well as in their branches (3 patients), in occipital arteries (2 patients) and also in vertebral arteries (3 patients).

Keywords:
18F-FDG PET/CT
Positron emission tomography
Giant cell arteritis
Large-vessel vasculitis
Resumen

El estudio con 18F-FDG PET/TC es útil en los pacientes con fiebre de origen desconocido y puede detectar la arteritis de células gigantes en las grandes arterias extracraneales. Sin embargo, por lo general se supone que las arterias temporales no pueden ser visualizadas por medio de PET/TC porque su diámetro es pequeño. Se examinó a tres pacientes con arteritis temporal mediante el protocolo PET/TC estándar de cuerpo completo (base del cráneo – mitad del muslo) seguido del protocolo PET/TC de cabeza para cerebro. En los tres pacientes se observó la alta acumulación de 18F-FDG en la aorta y en algunas arterias. Mediante el protocolo para cerebro se observó la intensa acumulación de 18F-FDG en las arterias temporales y sus ramas (3 pacientes), en las arterias occipitales (2 pacientes) y también en las arterias vertebrales (3 pacientes).

Palabras clave:
18F-FDG PET/TC
Tomografía por emisión de positrones
Arteritis de células gigantes
Vasculitis de vaso grande

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