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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) PET/CT imaging with somatostatin analogues for the assessment of neuroendocrine ...
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Vol. 38. Issue 6.
Pages 382-385 (November - December 2019)
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Vol. 38. Issue 6.
Pages 382-385 (November - December 2019)
Clinical note
PET/CT imaging with somatostatin analogues for the assessment of neuroendocrine tumours, initial experience
PET/TC con análogos de la somatostatina en el estudio de tumores neuroendocrinos, experiencia inicial
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M. Suárez-Piñeraa,
Corresponding author
40086@parcdesalutmar.cat

Corresponding author.
, L. Visab, L. Ilzarbec, A. Zugazagad, I. Povese, A. Mestre-Fuscoa, M. Iglesiasf
a Servicio de Medicina Nuclear, Diagnóstico por Imagen, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
b Servicio de Oncología Médica, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
c Servicio de Digestivo, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
d Servicio de Radiología, Diagnóstico por Imagen, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
e Servicio de Cirugía, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
f Anatomía Patológica, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
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Abstract

PET with somatostatin analogues (SSA PET/CT) enables the detection of cells with overexpression of somatostatin receptors, especially subtypes 2 and 5; this detection is variable depending on the type of molecule used. This is the basis for its use in the study of neuroendocrine tumours (NETs), which are characterized by an overexpression of these receptors in more than 80% of the subtypes. This PET is now being used in our country supported by the good results published by other groups, that were superior to those of other imaging techniques. We present two of the first cases of SSA-PET/CT with 68Ga-edotreotide (SomaKit TOC®) performed in our centre. SSA-PET/CT was the test that finally determined the clinical management of both patients.

Keywords:
PET/CT with somatostatin analogues
Neuroendocrine tumours
Somatostatin receptor
Resumen

La PET con análogos de la somatostatina permite detectar aquellas células con sobreexpresión de receptores de somatostatina, especialmente del subtipo 2 y 5, siendo variable esta detección según el tipo de molécula que se utilice. Esta es la base para su uso en el estudio de los tumores neuroendocrinos (NET), los cuales se caracterizan por presentar una sobreexpresión de estos receptores en más del 80% de los subtipos. Esta PET llega a nuestro país avalada por los buenos resultados publicados por otros grupos, superiores a los de otras técnicas de imagen. Presentamos dos de los primeros casos de PET con análogos de la somatostatina: 68Ga-edetreótida (SomaKit TOC®) realizados en nuestro centro. La PET fue la prueba que determinó finalmente el manejo clínico de ambos pacientes.

Palabras clave:
PET/TC con análogos de la somatostatina
Tumores neuroendocrinos
Receptores de la somatostatina

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