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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Peritoneal Cancer Index by 18F-FDG PET/TC pre and post-hyperthermic intraperiton...
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Vol. 35. Issue 5.
Pages 329-331 (September - October 2016)
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Vol. 35. Issue 5.
Pages 329-331 (September - October 2016)
Clinical note
Peritoneal Cancer Index by 18F-FDG PET/TC pre and post-hyperthermic intraperitoneal chemotherapy. Report of a case
Peritoneal Cancer Index mediante 18F-FDG PET/TC pre y poscirugía citorreductiva radical y quimioterapia intraperitoneal con hipertermia. A propósito de un caso
J.R. Garcia
Corresponding author
jrgarcia@cetir.es

Corresponding author.
, D. Villasboas-Rosciolesi, M. Soler, P. Bassa, M. Cozar, E. Riera
Unidad PET, CETIR-ERESA, Esplugues de Llobregat, Barcelona, Spain
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Abstract

Radical cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy increases survival in patients with end-stage peritoneal carcinomatosis, and who are under palliative therapy. The Peritoneal Cancer Index enables the tumor burden to be quantified during surgery, as well as treatment planning and patient prognosis. It is obtained by combining the tumor spread in 13 abdominal and pelvic regions with the largest tumor size. Fluorodeoxyglucose positron emission tomography/computed tomography is the technique of choice for those patients selected to undergo radical cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy, due to its higher detection rate of carcinomatosis, and since it allows extra-peritoneal disease staging. The simplified Peritoneal Cancer Index (9 regions defined by 2 transverse and 2 sagittal planes) obtained by fluorodeoxyglucose positron emission tomography/computed tomography allows correlation with the surgical procedure, therefore its standardization is advisable.

Keywords:
Peritoneal Cancer Index
18F-FDG PET/TC
Quantification
Hyperthermic intraperitoneal chemotherapy
Resumen

La cirugía citorreductora radical seguida de quimioterapia intraperitoneal con hipertermia aumenta la supervivencia de los pacientes con carcinomatosis peritoneal. El Peritoneal Cancer Index cuantifica el tumor en el acto quirúrgico y permite planificar el tratamiento y establecer el pronóstico de la enfermedad. Se obtiene combinando la distribución del tumor en 13 regiones abdominopélvicas con el tamaño de la lesión más grande. La tomografía por emisión de positrones/tomografía computarizada con fluorodesoxiglucosa es la técnica de elección en la selección de los pacientes candidatos a cirugía citorreductora radical seguida de quimioterapia intraperitoneal con hipertermia debido a su mayor tasa de detección de la carcinomatosis y a que, además, permite el diagnóstico de enfermedad extraperitoneal. El Peritoneal Cancer Index simplificado (9 regiones definidas por 2 planos transversales y 2 sagitales) obtenido mediante tomografía por emisión de positrones/tomografía computarizada con fluorodesoxiglucosa permite su correlación con el acto quirúrgico, siendo su estandarización aconsejable.

Palabras clave:
Peritoneal Cancer Index
18F-FDG PET/TC
Cuantificación
Quimioterapia intraperitoneal con hipertermia

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