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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) 18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis...
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Vol. 37. Issue 3.
Pages 172-174 (May - June 2018)
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Vol. 37. Issue 3.
Pages 172-174 (May - June 2018)
Clinical note
18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord
La 18F-FDG PET/TC ayuda a desenmascarar a la gran imitadora: un caso de neurosarcoidosis con implicación aislada en la mèc)dula espinal
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A. Gholamrezanezhad
Corresponding author
, L. Mehta
Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, USA
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Abstract

A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The 18F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as well as a mildly hypermetabolic bilateral hilar lymphadenopathy and a mildly hypermetabolic pulmonary nodule, suggestive of sarcoidosis versus metastasis. The diagnosis of sarcoidosis was supported by identifying non-caseating granuloma in the biopsy of the pulmonary nodule. The patient responded well to steroid-therapy, with the symptoms being resolved within 3 weeks.

Keywords:
Neurosarcoidosis
PET scan
18F-FDG ;Spinal cord
Pulmonary nodule ;
Resumen

Durante 4 semanas, un paciente varón de 36 años, sin historial clínico de relevancia, presentó entumecimiento en las extremidades inferiores, inestabilidad al andar, retención de orina y estreñimiento. La RM de la mèc)dula espinal mostró edema difuso en la mèc)dula dorsal cervicotorácica, así como imágenes de lesiones intramedulares sólidas indicativas de metástasis. Se realizó una 18F-FDG PET/TC para identificar la malignidad primaria de los focos hipermetabólicos dentro de la mèc)dula cervicotorácica, así como la leve linfoadenopatía hiliar bilateral hipermetabólica y los nódulos pulmonares hipermetabólicos indicativos de sarcoidosis frente a metástasis. El diagnóstico de sarcoidosis fue respaldado al identificarse un granuloma no caseificante en la biopsia del nódulo pulmonar. El paciente respondió bien al tratamiento con esteroides y los síntomas desaparecieron en 3 semanas.

Palabras clave:
Neurosarcoidosis
PET scan
18F-FDG
Mèc)dula espinal
Nódulo pulmonar ;

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