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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Utility of positron emission tomography with 18F-FDG in a case of juvenile recur...
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Vol. 32. Issue 6.
Pages 387-389 (November - December 2013)
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Vol. 32. Issue 6.
Pages 387-389 (November - December 2013)
Clinical note
Utility of positron emission tomography with 18F-FDG in a case of juvenile recurrent respiratory papillomatosis
Utilidad de la tomografía por emisión de positrones con 18F-FDG en un caso de papilomatosis pulmonar recurrente juvenil
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I. Navalesa,
Corresponding author
inavales@clinic.ub.es

Corresponding author.
, P. Paredesa, M. Colsb, A. Perissinottia, M. Vancellsc, F. Ponsa,d
a Servicio de Medicina Nuclear, Hospital Clínic, Barcelona, Spain
b Servicio de Pediatría, Hospital Sant Joan de Déu, Universidad de Barcelona, Barcelona, Spain
c Servicio de Cirugía Pediátrica, Hospital Sant Joan de Déu, Universidad de Barcelona, Barcelona, Spain
d Servicio de Medicina Nuclear, Hospital Clínic, Universidad de Barcelona, Barcelona, Spain
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Abstract

Juvenile recurrent respiratory papillomatosis (JRRP) is an infectious disease caused by the growth of papillomas in the airway. Up to 4% of these cases degenerate into squamous cell carcinoma. We present the case of a 17-year-old female patient with JRRP in which the utility of 18F-FDG-PET/CT in the characterization of suspicious papillomatous lesions of malignancy is evaluated. Morphometabolic techniques, CT scan and PET/CT scans were suggestive of malignancy. However, this was not confirmed in the histopathological analysis after its resection.

The 18F-FDG-PET/CT does not seem to be a useful tool for early detection of malignancy in JRRP. However, it does increase the diagnostic accuracy of the biopsy as it identifies the most active lesions and, therefore, those most likely to be malignant.

Keywords:
Recurrent respiratory papillomatosis
Positron emission tomography
Human papillomavirus
Resumen

La papilomatosis pulmonar recurrente juvenil (PPRJ) es una enfermedad infecciosa que provoca el crecimiento de papilomas en la vía respiratoria en la que hasta en un 4% de los casos degeneran hacia un carcinoma de células escamosas. Presentamos el caso de una paciente de 17 años con PPRJ en la que se valora la utilidad de la 18F-FDG-PET/TC ante la sospecha de malignización de las lesiones papilomatosas. Las técnicas de imagen morfometabólicas, la TC y la PET/TC fueron sugestivas de malignidad. Sin embargo, esta no fue confirmada en el análisis anatomopatológico tras su resección.

La FDG-PET/TC no parece una herramienta útil para la detección precoz de malignidad en la PPRJ, aunque sí aumenta la rentabilidad diagnóstica de la biopsia al identificar las lesiones más activas y, por lo tanto, con mayor posibilidad de ser malignas.

Palabras clave:
Papilomatosis pulmonar recurrente
Tomografía por emisión de positrones
Virus papiloma humano

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