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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Treatment of cystic craniopharyngioma with 90Y-Colloid. Four clinical cases
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Vol. 32. Issue 5.
Pages 321-323 (September - October 2013)
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Vol. 32. Issue 5.
Pages 321-323 (September - October 2013)
Clinical note
Treatment of cystic craniopharyngioma with 90Y-Colloid. Four clinical cases
Tratamiento del craneofaringioma quístico con 90Y-coloide. Presentación de 4 casos clínicos
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A. Sabaté-Lloberaa,
Corresponding author
asabatell@bellvitgehospital.cat

Corresponding author.
, J.G. Rojas-Camachoa, J. Mora Salvadóa, J.J. Acebes Martínb, A. Rodríguez-Gaséna, D. Ramal Leivaa, J. Martín-Comína
a Servicio de Medicina Nuclear, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
b Servicio de Neurocirurgia, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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Table 1. Formulas for calculation of cyst volume and the dose of 90Y to be injected.
Abstract

Craniopharyngioma is a histologically benign and frequently cystic intracranial tumor. It may present aggressive behavior due to compression from nearby structures. Its therapeutic management is complicated because although surgery is the usual treatment of choice, it is not exempt of high morbidity and mortality and frequent tumor recurrence. In craniopharyngiomas with a significant cystic component, internal irradiation with radioactive isotopes is a therapeutic alternative to conventional treatments.

We present the cases of four patients with cystic craniopharyngiomas who were treated with intracystic administration of 90Y-colloid, and their evolution after the treatment.

Keywords:
Cystic craniopharyngioma
Yttrium-90 colloid
Intracavitary irradiation
Guided radiotherapy
Resumen

El craneofaringioma es un tumor intracraneal histológicamente benigno y frecuentemente quístico, que puede presentar comportamiento agresivo por compresión de estructuras vecinas. Su manejo terapéutico es complicado, ya que si bien el tratamiento de elección suele ser la cirugía, esta no está exenta de una gran morbimortalidad y recidiva tumoral frecuente. En aquellos craneofaringiomas con un componente quístico importante, la irradiación interna del tumor con isótopos radiactivos supone una alternativa a los tratamientos convencionales.

Se presentan cuatro casos de pacientes con craneofaringiomas quísticos tratados mediante administración intraquística con 90Y-coloide, y su evolución después del tratamiento.

Palabras clave:
Craneofaringioma quístico
Itrio-90 coloide
Irradiación intracavitaria
Radioterapia guiada

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