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Inicio Actas Urológicas Españolas Tratamiento tópico con Imiquimod crema al 5% de la enfermedad de Bowen del pene
Journal Information
Vol. 29. Issue 8.
Pages 797-800 (January 2005)
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Vol. 29. Issue 8.
Pages 797-800 (January 2005)
Tratamiento tópico con Imiquimod crema al 5% de la enfermedad de Bowen del pene
Treatment of bowen`s disease of the penis with imiquimod 5% cream
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1956
E. de Diego Rodríguez1
Corresponding author
e.diego@telefonica.net

Dr. E. de Diego Rodríguez. C/ Miguel de Unamuno, 6, 5º B. 39012 Santander (Cantabria)
, A. Villanueva Peña, A. Hernández Castrillo
Servicio de Urología.
J. Mª Gómez Ortega*
* Servicio de Anatomía-patológica. Hospital Comarcal de Laredo (Cantabria).
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Resumen

Presentamos una alternativa más de tratamiento para las neoplasias intraepiteliales de pene (enfermedad de Bowen) mediante la aplicación tópica de imiquimod crema al 5% 3 días alternos a la semana durante 5 semanas. El imiquimod es una imidazoquinolona, modificador de la respuesta inmune con efectos antiviral y antitumoral indirectos, que presenta escasos efectos secundarios a nivel local y que puede constituir una opción más en el tratamiento de la enfermedad de Bowen del pene.

Palabras clave:
Carcinoma in situ
Neoplasia de pene
Neoplasia intraepitelial
Abstract

We present an alternative treatment of the intraepithelial neoplasms of penis (Bowen`s disease), the topical application of imiquimod 5% cream. It was applied 3 times weekly for 5 weeks. Imiquimod is an imidazoquinolone immune response modifier that has been shown to have indirect antiviral and antitumor effects with few adverse effects. Imiquimod 5% cream may represent an alternative treatment option for Bowen`s disease.

Key words:
Carcinoma in situ
Penile neoplasms
Intraepithelial neoplasms

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