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Endocrinol Nutr 2004;51:42-7 - DOI: 10.1016/S1575-0922(04)74583-0
Uso y abuso de los suplementos dietéticos
J. Álvarez
Sección de Endocrinología y Nutrición. Hospital Universitario Príncipe de Asturias. Alcalá de Henares. Madrid. España
Recibido 16 octubre 2003, Aceptado 24 noviembre 2003

Las vitaminas y los minerales constituyen los micronutrientes esenciales en la nutrición del individuo para mantener un adecuado equilibrio en el metabolismo intermediario. Diversos estudios han demostrado los efectos beneficiosos de micronutrientes como el ácido fólico, la vitamina E, el selenio y el calcio en la prevención y tratamiento de algunas enfermedades. Los criterios de la suplementación deben establecerse considerando los estudios de eficacia de los suplementos y las evidencias de seguridad de éstos. El establecimiento de programas de educación sanitaria que informen de estos aspectos a la población podría contribuir al uso racional de los suplementos nutricionales.

Vitamins and minerals are essential micronutrients in human nutrition to maintain adequate intermediate metabolism. Several studies have demonstrated the benefits of micronutrients such as folic acid, vitamin E, selenium, and calcium in preventing or treating certain diseases. The criteria for supplementation should be established, based on safety and efficacy studies. Nutritional education programs aimed at the general public could contribute to the rational use of nutritional supplements.

Palabras clave
Suplementos nutricionales, Seguridad, Eficacia, Uso racional
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A. Entrala
Vitaminas. En: SENC, editor. Guías alimentarias para la población española
pp. 249-265
A. Entrala
Minerales. En: SENC, Guías alimentarias para la población española
pp. 266-275
NRC (National Research Council)
Recommended dietary allowances: report of the Food and Nutrition Board. Commission on Life Sciences
pp. 195
Micronutrient suplementation in the critically ill patient
Strategies for clinical practice
J Trauma, 51 (2001), pp. 601-620
P.A. Lachance
Overview of Key nutrients: micronutrients aspects
Nutr Rev, 56 (1998), pp. S34-S39
W.R. Bidlack
Interrelationships of Food, Nutrition, Diet and Health. The National Association of State Universities and Land Grant Colleges White Paper
J Am Coll Nutr, 15 (1996), pp. 422-433
R.M. Ortega
Suplementos nutricionales. En: SENC, Guías alimentarias para la población española
pp. 313-320
L.A. Berner,F.M. Clydesdale,J.S. Douglass
Fortification contributed greatly to vitamin and mineral intakes in the United States, 1989-1991
J Nutr, 131 (2001), pp. 2177-2183
L. Serra,L. Ribas,P. Saiz de Bustamante,F. López,M. Barbachano
Consumo de suplementos vitamínico-minerales en la población española (1996)
Nutr Clin, 16 (1996), pp. 7-15
J. Aranceta,L. Serra,C. Pérez,J. Llopis,J. Mataix,L. Ribas
Las vitaminas en la alimentación de los españoles. Estudio eVe. Análisis en población general
Gila A editores. Libro blanco, pp. 49-93
S. Jasti,A.M. Siega-Riz,M.E. Bentley
Dietary supplement use in the context of health disparities: cultural, ethnic and demographic determinants of use
J Nutr, 133 (2003), pp. S2010-S2013
E. Frank,A. Bendich,M. Denniston
Use of vitamin-mineral supplements by female physicians in the United States
Am J Clin Nutr, 72 (2000), pp. 969-975
R. Chernoff
Nutrition and Health Promotion in Older Adults [series A]
J Gerontol, 56A (2001), pp. 47-53
A. Entrala
Malnutrición en los países desarrollados. Carencias subclínicas de vitaminas
Tratado de nutrición, pp. 771-784
J. Mataix
Requerimientos nutricionales e ingestas recomendadas de nutrientes
Tratado de nutrición, pp. 575-587
Food and Nutrition Board
Recommended dietary allowances 10th ed
P. Weber,A. Bendich,W. Schalch
Vitamin C and human health. A review of recent data relevant to human reuqerimients
Intern J Vit Nutr Res, 66 (1995), pp. 19-30
K.T. Zondervan,M.C. Ocke,H.A. Smit,J.C. Seidell
Do deitary and supplementary intakes of antioxidants differ with smoking status?
Int J Epidemiol, 25 (1996), pp. 70-79
C.E. Cross,M. Traber,J. Eiserich,A. Van der Vliet
Micronutrient antioxidants and smoking
Br Med Bull, 55 (1999), pp. 691-704
R.M. Ortega,M.C. Mena,M. Faci,J.F. Santana,L. Serra
Situación en vitaminas de la población española. Metaanálisis de los estudios realizados en España en el periodo 1990-1999
editores. Libro blanco. Las vitaminas en la alimentación de los españoles. Estudio eVe, pp. 95-142
J.N. Hathcock
Vitamins and minerals: efficacy and safety
Am J Clin Nutr, 66 (1997), pp. 427-437
Committe on Nutrition and Foods for Special Dietary Uses, Codex Alimentarius Commission
Draft guidelines for deitary supplements (vitamins and minerals) [ALINORM 95/26]
Food and Drug Administration
Food Labeling: health claims and label statements folate and neural tube defects
Fed Regist, 61 (1996), pp. 8752-8781
A. Sharma,K. Prasad,K.V. Rao
Identification of an appropiate strategy to control anemia in adolescent girls of poor communities
Indian Pediatr, 37 (2000), pp. 261-267
C. Gopalan
Multiple Micronutrient Supplementation in Pregnacy
Nutr Rev, 60 (2002), pp. S2-S6
J. Blumberg
Nutritional Needs of Senior
J Am Coll Nutr, 16 (1997), pp. 517-523
O. Moreiras,B. Beltrán,C. Cuadrado
Guías dietéticas en la vejez. En: SENC, editor. Guías alimentarias para la población española
pp. 379-398
K.G. Losonezy,T.B. Harris,R.J. Havlik
Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the established populations for epidemiologic studies of elderly
Am J Clin Nutr, 64 (1996), pp. 190-196
J.A. Ward
Should antioxidants vitamins be routinely recommended for older people?
Drugs Aging, 12 (1998), pp. 169-175
H. Baker,B. De Angelis,E.R. Baker,O. Frank,S.P. Jaslow
Lack of effect of 1 year intake of high-dose vitamin and mineral supplement on cognitive function of elderly woman
Gerontology, 45 (1999), pp. 195-199 http://dx.doi.org/22086
D.L. McKay,G. Perrone,H. Rasmussen,G. Dallal,W. Hartman,G. Cao
The effects of a multivitamin/mineral supplement on micromutrient status, antioxidant capacity and cytokine production in healthly older adults consuming a fortified diet
J Am Coll Nutr, 19 (2000), pp. 613-621
J. Little
Problems and approches in investigating the role of micronutrients in the aetiology of cancer in humans
Br Med Bull, 55 (1999), pp. 600-618
M.J. Stampfer,E.B. Rimm
Epidemiologic evidence for vitamin E in prevention of cardiovascular disease
Am J Clin Nutr, 62 (1995), pp. S1365-S1369
E.B. Rimm,M.J. Stampfer,A. Ascherio,E. Giovannucci,G.A. Colditz,W.C. Willett
Vitamin E consumption and the risk of coronary heart disease in men
N Engl J Med, 328 (1993), pp. 1450-1456 http://dx.doi.org/10.1056/NEJM199305203282004
R.H. Fletcher,K.M. Fairfield
Vitamins for chronic disease prevention in adults. Clinical applications
JAMA, 287 (2002), pp. 3127-3129
T.A. Barringer,J.K. Kirk,A.C. Santaniello,K.L. Foley,R. Michielutte
Effect of a Multivitamin and mineral supplement on infection and quality of life
Ann Intern Med, 138 (2003), pp. 365-371
A.R. Kristal,J.L. Stanford,J.H. Cohen,K. Wicklund,R.E. Patterson
Vitamin and mineral supplement use is associated with reduced risk of prostate cancer
Cancer Epidemiol Biomarkers Prev, 8 (1999), pp. 887-892
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
N Engl J Med, 330 (1994), pp. 1029-1035 http://dx.doi.org/10.1056/NEJM199404143301501
P. Knekt,A. Aromaa,J. Maatela
Vitamin E and cancer prevention
Am J Clin Nutr, 53 (1991), pp. S283-S286
S.R. Tannebaum,J.S. Wishnok,C.D. Leaf
Inhibition of nitrosamine formation by ascorbic acid
Am J Clin Nutr, 53 (1991), pp. S287S-S293S
E.R. Greenberg,J.A. Baron,T.D. Tosteson
A clinical trial of antioxidant vitamins to prevent colorectal adenoma
N Engl J Med, 331 (1994), pp. 141-147 http://dx.doi.org/10.1056/NEJM199407213310301
A. Mijan,A. Pérez
Cálculo de necesidades en el paciente oncológico. En: Soporte nutricional en el paciente oncológico
pp. 57-76
C.J. Fuller,M. Chandalia,A. Grag,S.M. Grundy,I. Jialal
RRR alfa-tocopheryl acetate supplementation at pharmacologic doses decreases low-density-lipoprotein oxidative susceptibility but not protein glycation in patiens with diabetes mellitus
Am J Clin Nutr, 63 (1996), pp. 753-759
A.K. Adams,E.O. Wermuth,P.E. McBride
Antioxidant vitamins and the prevention of coronary heart disease
Am Family Phisician, 60 (1999), pp. 895-899
J.B. Vincent
Quest for the molecular mecahanism of chromium action and its relationship to diabetes
Nutr Rev, 58 (2000), pp. 67-72
A. Mezzetti,F. Cipollone,F. Cuccurullo
Oxidative stress and cardiovacular complications in diabetes: isoprostanes as new markers on an old paradigm
Cardiovasc Res, 47 (2000), pp. 475-488
M.J. Salgueiro,N. Krebs,M.B. Zubillaga,R. Weill,E. Postaire,A.E. Lysionek
Zinc and diabetes mellitus Is there a need of zinc supplementation in diabetes mellitus patients?
Biol Trace Elem Res, 81 (2001), pp. 215-228 http://dx.doi.org/10.1385/BTER:81:3:215
P. Faure,P.Y. Benhamou,A. Perard,S. Halimi,A.M. Roussel
Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation
Eur J Clin Nutr, 49 (1995), pp. 282-288
R.A. Anderson
Chromium, glucose intolerance and diabetes
J Am Coll Nutr, 17 (1998), pp. 548-555
R.A. DiSilvestro
Zinc in relation to diabetes and oxidative disease
J Nutr, 130 (2000), pp. S1509-S1511
Food and Drugs Administration
Food labeling: health claims calcium and osteoporosis
Fed Regist, 61 (1996), pp. 8752-8781
L. Troppmann,K. Gray-Donald,T. John
Supplement use: is there any nutritional benefit?
J Am Diet Assoc, 102 (2002), pp. 818-825
S. Hercberg,P. Preziosi,P. Galan,H. Faure,J. Arnaud,N. Duport,S.U. The
VI. MAX STUDY: a primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular disease and cancers
Food Chem Toxicol, 37 (1999), pp. 925-930

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Correspondencia: Dra. J. Álvarez Hernández. Servicio de Endocrinología y Nutrición. Hospital Universitario Príncipe de Asturias. Campus Universitario. Crta Alcalá-Meco, s/n. 28805 Alcalá de Henares. Madrid. España (J. Álvarez )
Copyright © 2004. Sociedad Española de Endocrinología y Nutrición