array:23 [ "pii" => "S0001651906787404" "issn" => "00016519" "doi" => "10.1016/S0001-6519(06)78740-4" "estado" => "S300" "fechaPublicacion" => "2006-11-01" "aid" => "78740" "copyright" => "Elsevier España, S.L.. Todos los derechos reservados" "copyrightAnyo" => "2001" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Acta Otorrinolaringol Esp. 2006;57:419-24" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2062 "formatos" => array:3 [ "EPUB" => 35 "HTML" => 554 "PDF" => 1473 ] ] "itemSiguiente" => array:18 [ "pii" => "S0001651906787416" "issn" => "00016519" "doi" => "10.1016/S0001-6519(06)78741-6" "estado" => "S300" "fechaPublicacion" => "2006-11-01" "aid" => "78741" "copyright" => "Elsevier España, S.L." 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"apellidos" => "Morales-Angulo" ] ] ] 1 => array:2 [ "autoresLista" => "J. Gallo-Terán" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Gallo-Terán" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001651906787416?idApp=UINPBA00004N" "url" => "/00016519/0000005700000009/v1_201304231454/S0001651906787416/v1_201304231454/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0001651906787398" "issn" => "00016519" "doi" => "10.1016/S0001-6519(06)78739-8" "estado" => "S300" "fechaPublicacion" => "2006-11-01" "aid" => "78739" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Acta Otorrinolaringol Esp. 2006;57:412-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3766 "formatos" => array:3 [ "EPUB" => 46 "HTML" => 1658 "PDF" => 2062 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Diagnóstico y tratamiento de los paragangliomas carotídeos. Presentación de nueve casos y revisión de la literatura" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "412" "paginaFinal" => "418" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Deep neck infectious: Etiology, bacteriology and treatment" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. Gil-Carcedo, L.M. Gil-Carcedo, L.A. Vallejo, D. Herrero, C. Ortega" "autores" => array:5 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Gil-Carcedo" ] 1 => array:2 [ "nombre" => "L.M." "apellidos" => "Gil-Carcedo" ] 2 => array:2 [ "nombre" => "L.A." "apellidos" => "Vallejo" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Herrero" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Ortega" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001651906787398?idApp=UINPBA00004N" "url" => "/00016519/0000005700000009/v1_201304231454/S0001651906787398/v1_201304231454/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Carcinoma epidermoide de laringe estadio IV. Evolución a largo plazo" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "419" "paginaFinal" => "424" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Herranz González-Botas, J.C. Vázquez Barro" "autores" => array:2 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "Herranz González-Botas" "email" => array:1 [ 0 => "jhg@canalejo.org" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "J.C." "apellidos" => "Vázquez Barro" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Otorrinolaringología. Hospital Universitario Juan Canalejo. A Coruña" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1." "correspondencia" => "Correspondencia: Jesús Herranz González-Botas Rua Courel, 6 15179 Oleiros (A Coruña)" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Epidermoid carcinoma larynx in stage IV" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-01-23" "fechaAceptado" => "2006-08-21" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec81803" "palabras" => array:5 [ 0 => "Cáncer de laringe" 1 => "Cirugía" 2 => "Recidiva" 3 => "Metástasis" 4 => "Segundo primario" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec81802" "palabras" => array:5 [ 0 => "Larynx carcinoma" 1 => "Surgery" 2 => "Recurrence" 3 => "Distant metastasis" 4 => "Second primary" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Analizar supervivencia, recidiva local, regional, a distancia y segundos primarios en estadios IV de laringe tratados con cirugía y radioterapia.</p> <span class="elsevierStyleSectionTitle">Material</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de 147 pacientes tratados con cirugía ± radioterapia, con un seguimiento mínimo de 5 años.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Supervivencia global y causa específica a 5 y 10 años de 42%, 35% y 49%, 45,8% respectivamente. Control locoregional del 57,7 % y 54,7% a los 5 y 10 años. Recidivas locales 25,7%, recidivas regionales 74,2%, y metástasis a distancia 10,9%. Segundos primarios 12%, el 50% en pulmón. Se analizan factores que pueden influir en la supervivencia.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">En nuestra experiencia, la cirugía, con radioterapia complementaria en N+, permite curar un 45% de los estadios IV de laringe. La recidiva regional es la causa más frecuente de fracaso, influida por el N+, apareciendo en los primeros 36 meses de evolución.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine the survival, loco-regional control, distant metastases and second primary in stage IV laryngeal carcinoma treated by surgery and radiotherapy.</p> <span class="elsevierStyleSectionTitle">Material</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of 147 patients treated with surgery and radiotherapy with a 5 year minimun follow-up.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Overall and cause specific survival at 5 and 10 years was 42%, 35% and 49%, 45.8% respectively. Loco-regional control was 57.7 % and 54.7% at 5 and 10 years. Local recurrences presented in 25.7%, regional recurrences in 74.2%, and distant metastases 10.9%. Second primary tumors developed in 12% of the patients, 50% of the cases in the lungs. Factors related to survival are evaluated.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">In our experience, surgery with postoperative radiotherapy in N+, controls 45% of stage IV laryngeal carcinoma. Regional recurrencies are the main cause of failure, more frequent in N+ patientes, present in the first 36 months after treatment.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:33 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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Carcinoma epidermoide de laringe estadio IV. Evolución a largo plazo
Epidermoid carcinoma larynx in stage IV
J. Herranz González-Botas1
, J.C. Vázquez Barro
Autor para correspondencia
jhg@canalejo.org
Correspondencia: Jesús Herranz González-Botas Rua Courel, 6 15179 Oleiros (A Coruña)
Correspondencia: Jesús Herranz González-Botas Rua Courel, 6 15179 Oleiros (A Coruña)
Servicio de Otorrinolaringología. Hospital Universitario Juan Canalejo. A Coruña