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Inicio Vacunas The co-infection of SARS-CoV-2 with atypical bacterial respiratory infections: A...
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Vol. 25. Issue 2.
Pages 233-238 (April - June 2024)
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Vol. 25. Issue 2.
Pages 233-238 (April - June 2024)
Review article
The co-infection of SARS-CoV-2 with atypical bacterial respiratory infections: A mini review
La coinfección de SARS-CoV-2 con infecciones respiratorias bacterianas atípicas: Una mini revision
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325
Fateme Taheri1, Soheil Vesal2,
, Parnian Goudarzi3,
, Zahra Sahafnejad4,
, Amin Khoshbayan5,
Corresponding author
khoshbayan.a@iums.ac.ir

Corresponding author at: Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
1 Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Molecular Genetics, Faculty of Basic Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran
3 Department of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran
4 Department of Biophysics, Faculty of Biological Sciences, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran P.O. Box 14115-111, Iran
5 Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
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Tables (2)
Table 1. The signs and clinical outcomes from different studies.
Table 2. The clinical and laboratory finding of COVID-19 co-infected patients from different studies.
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Abstract

In 2019, the Coronavirus disease (COVID-19) rapidly spread worldwide and posed a global threat. The co-infection among COVID-19 patients was reported variable in different studies. However, it could reach 50% of non-survivor patients. Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila are responsible for respiratory infections and also can act as co-pathogens with COVID-19, making their detection challenging. These bacteria exhibit similar clinical signs to COVID-19, leading to potential oversight. Furthermore, treating these bacteria requires a different antibiotic regimen compared to typical respiratory bacterial agents. Thus, recognizing the clinical characteristics, laboratory findings, and outcomes of co-infections is crucial for improving understanding and treatment strategies.

Keywords:
Chlamydia pneumoniae
Mycoplasma pneumoniae
Legionella pneumophila
SARS-CoV-2
COVID-19
Respiratory infection
Palabras clave:
Chlamydia pneumoniae
Mycoplasma pneumoniae
Legionella pneumophila
SARS-CoV-2
COVID-19
Infección respiratoria
Resumen

En 2019, la enfermedad del coronavirus (COVID-19) se propagó rápidamente por todo el mundo y representó una amenaza mundial. La coinfección entre pacientes con COVID-19 se informó de forma variable en diferentes estudios. Sin embargo, podría llegar al 50% de los pacientes que no sobreviven. Chlamydia pneumoniae, Mycoplasma pneumoniae y Legionella pneumophila son responsables de infecciones respiratorias y también pueden actuar como co-patógenos con COVID-19, lo que dificulta su detección. Estas bacterias exhiben signos clínicos similares a los de COVID-19, lo que lleva a una posible supervisión. Además, el tratamiento de estas bacterias requiere un régimen antibiótico diferente en comparación con los agentes bacterianos respiratorios típicos. Por lo tanto, reconocer las características clínicas, los hallazgos de laboratorio y los resultados de las coinfecciones es crucial para mejorar la comprensión y las estrategias de tratamiento.

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