was read the article
array:24 [ "pii" => "S2444382419302366" "issn" => "24443824" "doi" => "10.1016/j.gastre.2019.06.005" "estado" => "S300" "fechaPublicacion" => "2019-12-01" "aid" => "1418" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2019" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2019;42:630-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0210570519301608" "issn" => "02105705" "doi" => "10.1016/j.gastrohep.2019.06.002" "estado" => "S300" "fechaPublicacion" => "2019-12-01" "aid" => "1418" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2019;42:630-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 112 "formatos" => array:2 [ "HTML" => 78 "PDF" => 34 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científica</span>" "titulo" => "Cerebelitis autoinmune en enfermedad de Crohn" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "630" "paginaFinal" => "631" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Autoimmune cerebellitis in Crohn's disease" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1052 "Ancho" => 905 "Tamanyo" => 58374 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Resonancia magnética de cráneo.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Enrique Práxedes González, Marta Lázaro Sáez, Álvaro Hernández Martínez, Esteban Alessandro Vogt Sánchez, Antonio Arjona Padillo, José Luis Vega Sáenz" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Enrique" "apellidos" => "Práxedes González" ] 1 => array:2 [ "nombre" => "Marta" "apellidos" => "Lázaro Sáez" ] 2 => array:2 [ "nombre" => "Álvaro" "apellidos" => "Hernández Martínez" ] 3 => array:2 [ "nombre" => "Esteban Alessandro" "apellidos" => "Vogt Sánchez" ] 4 => array:2 [ "nombre" => "Antonio" "apellidos" => "Arjona Padillo" ] 5 => array:2 [ "nombre" => "José Luis" "apellidos" => "Vega Sáenz" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2444382419302366" "doi" => "10.1016/j.gastre.2019.06.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382419302366?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570519301608?idApp=UINPBA00004N" "url" => "/02105705/0000004200000010/v1_201912120625/S0210570519301608/v1_201912120625/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2444382419302378" "issn" => "24443824" "doi" => "10.1016/j.gastre.2019.06.006" "estado" => "S300" "fechaPublicacion" => "2019-12-01" "aid" => "1421" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Gastroenterol Hepatol. 2019;42:632-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 9 "HTML" => 9 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image of the month</span>" "titulo" => "Black esophagus, is it as bad as it seems?" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "632" "paginaFinal" => "633" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Esófago negro ¿es tan malo como parece?" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 807 "Ancho" => 1007 "Tamanyo" => 133605 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Endoscopic image of medial oesophagus showing necrotic oesophageal mucosa spreading proximally from the distal oesophagus.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Amparo Roa Colomo, Adelina García Robles, Elena Ruiz Escolano" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Amparo" "apellidos" => "Roa Colomo" ] 1 => array:2 [ "nombre" => "Adelina" "apellidos" => "García Robles" ] 2 => array:2 [ "nombre" => "Elena" "apellidos" => "Ruiz Escolano" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210570519301657" "doi" => "10.1016/j.gastrohep.2019.06.004" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570519301657?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382419302378?idApp=UINPBA00004N" "url" => "/24443824/0000004200000010/v1_201912241024/S2444382419302378/v1_201912241024/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2444382419302354" "issn" => "24443824" "doi" => "10.1016/j.gastre.2019.06.004" "estado" => "S300" "fechaPublicacion" => "2019-12-01" "aid" => "1416" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2019;42:629-30" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific letter</span>" "titulo" => "Drug-induced liver injury due to mesterolone: A case report" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "629" "paginaFinal" => "630" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Daño hepático inducido por mesterolona: a propósito de un caso" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1010 "Ancho" => 2205 "Tamanyo" => 99377 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Chronological course of laboratory abnormalities and their temporal relationship to the use of the drug responsible.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Domingo Pérez Palacios, Álvaro Giráldez Gallego, Virginia Carballo Rubio, Ana Solà Fernández, Juan Manuel Pascasio Acevedo" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Domingo" "apellidos" => "Pérez Palacios" ] 1 => array:2 [ "nombre" => "Álvaro" "apellidos" => "Giráldez Gallego" ] 2 => array:2 [ "nombre" => "Virginia" "apellidos" => "Carballo Rubio" ] 3 => array:2 [ "nombre" => "Ana" "apellidos" => "Solà Fernández" ] 4 => array:2 [ "nombre" => "Juan Manuel" "apellidos" => "Pascasio Acevedo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S021057051930158X" "doi" => "10.1016/j.gastrohep.2019.06.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021057051930158X?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382419302354?idApp=UINPBA00004N" "url" => "/24443824/0000004200000010/v1_201912241024/S2444382419302354/v1_201912241024/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific letter</span>" "titulo" => "Autoimmune cerebellitis in Crohn’s disease" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "630" "paginaFinal" => "631" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Enrique Práxedes González, Marta Lázaro Sáez, Álvaro Hernández Martínez, Esteban Alessandro Vogt Sánchez, Antonio Arjona Padillo, José Luis Vega Sáenz" "autores" => array:6 [ 0 => array:3 [ "nombre" => "Enrique" "apellidos" => "Práxedes González" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 1 => array:4 [ "nombre" => "Marta" "apellidos" => "Lázaro Sáez" "email" => array:1 [ 0 => "alatriste83@hotmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Álvaro" "apellidos" => "Hernández Martínez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Esteban Alessandro" "apellidos" => "Vogt Sánchez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 4 => array:3 [ "nombre" => "Antonio" "apellidos" => "Arjona Padillo" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "José Luis" "apellidos" => "Vega Sáenz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Gestión Clínica de Aparato Digestivo, Complejo Hospitalario Torrecárdenas, Almería, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidad de Neurología Clínica y Diagnóstica, Complejo Hospitalario Torrecárdenas, Almería, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Cerebelitis autoinmune en enfermedad de Crohn" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1046 "Ancho" => 900 "Tamanyo" => 66803 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Magnetic resonance imaging of the head.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Acute cerebellitis is an inflammatory condition that often involves an infectious aetiology and usually follows a benign course. Cases of autoimmune origin are rare, and cases associated with inflammatory bowel disease are anecdotal. Clinical suspicion, as well as its correlation with complementary tests and a congruent therapeutic response, leads in these few cases to the diagnosis of the condition.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 37-year-old-male with a personal history of Crohn’s disease in the ileum featuring a penetrating pattern with entero-enteric and ileo-vesical fistulas for which he had undergone surgery, on treatment with 40 mg of adalimumab weekly, went in for left hemicranial headache accompanied by paresthesia in his upper limbs and blurred vision in his left eye.</p><p id="par0015" class="elsevierStylePara elsevierViewall">On examination, the patient was alert and orientated, presenting intermittent horizontal diplopia, paresis on abduction of his left eye with no associated diplopia, hyperreflexia and postural tremor in all four limbs, with no dysmetria or dysdiadochokinesia. While standing, he maintained his balance and presented a gait with a slight increase in base of support.</p><p id="par0020" class="elsevierStylePara elsevierViewall">He underwent laboratory testing which showed: glucose 114 mg/dl; urea 18 mg/dl; creatinine 0.57 mg/dl; total bilirubin 0.46 mg/dl; GGT 55 U/l; GOT 17 U/l; GPT 36 U/l; alkaline phosphatase 86 U/l; Na 143 mEq/l; K 3.69 mEq/l; C-reactive protein 0.45 mg/dl; haemoglobin 12.5 g/dl; leukocytes 7,200/mm<span class="elsevierStyleSup">3</span>; platelets 341,000/mm<span class="elsevierStyleSup">3</span>; aPTT 24 s and D-dimer 0.70 mg/l. No abnormalities were found in thyroid hormones, immunoglobulins G, A and M, vitamin E, vitamin B<span class="elsevierStyleInf">12</span> or folic acid. Serology for HIV, syphilis, toxoplasma, CMV, Epstein–Barr virus, brucella, <span class="elsevierStyleItalic">Borrelia burgdorferi</span>, <span class="elsevierStyleItalic">Mycoplasma pneumoniae</span> and <span class="elsevierStyleItalic">Chlamydophila pneumoniae</span> was negative.</p><p id="par0025" class="elsevierStylePara elsevierViewall">A CT scan of the head showed a slight diminishment of the extra-axial spaces in the posterior fossa with slight dilation of the third ventricle and lateral ventricles, whereupon cerebral venous thrombosis was ruled out. A thoracoabdominal CT scan and lumbar puncture showed no significant findings. Magnetic resonance imaging of the brain was ordered and reported an increased signal on T2 and flair in the cerebellar lobes, with a compression effect on the fourth ventricle, accompanied by a slight drop in the cerebellar tonsils in the context of signs of hypertension in the posterior fossa secondary to cerebellitis, of probable autoimmune aetiology (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Following empirical intravenous treatment with 50 mg of methylprednisolone every 24 h, the patient showed clinical improvement and remained asymptomatic following five days of treatment, with no signs of recurrence following six months of follow-up on an outpatient basis.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">The search for an aetiology led to further blood testing, which revealed positive antinuclear antibodies (titre 1/160) with a mottled pattern. These things, together with the patient’s good clinical response to treatment and imaging test findings, led to a diagnosis of autoimmune cerebellitis in a patient with Crohn’s disease.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Acute cerebellitis is an isolated clinical syndrome that characteristically affects a paediatric population. In most cases, it involves an infectious, post-infectious or post-vaccine phenomenon, and its course is usually benign. This disorder is rare in adults and has a varied aetiology, with few cases of autoimmune origin,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> in which it is possible to distinguish cases associated with paraneoplastic syndromes from idiopathic cases.</p><p id="par0040" class="elsevierStylePara elsevierViewall">The majority of neurological disorders associated with inflammatory bowel disease include cerebrovascular disease, peripheral neuropathies and demyelinating diseases; the finding of hypercoagulation phenomena promotes the development of venous sinus thrombosis.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Clinically, it presents with varied manifestations ranging from mild cerebellar signs to signs and symptoms characteristic of brain stem impairment. Generally, the syndrome starts with ataxia, myoclonus and spontaneous abnormalities of eye movements, to which headache, nausea, fever, altered level of consciousness, seizures, meningeal signs and other cerebellar signs are added.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Radiologic imaging of cerebellitis is variable: a CT scan may reveal modest low-density symmetrical and bilateral changes in the cerebellar hemispheres, which may be overlooked. Magnetic resonance imaging showed hypointense signals on T1 and hyperintense signals on T2 and sometimes cerebellar impairment may extend to the brain stem.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">Treatment varies by aetiology and clinical course, ranging from medical treatment to approaches that involve surgical decompression and external ventricular drainage in cases of obstructive hydrocephalus secondary to fulminant cerebellitis. In general, as in inflammatory bowel disease, management of this condition is based on the use of corticosteroids and immunosuppressants.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> However, the rarity of these cases makes it difficult to conduct studies on the potential benefits of immunosuppressive treatment for the condition’s course and recurrence.</p><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conflicts of interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0020" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Práxedes González E, Lázaro Sáez M, Hérnández Martínez Á, Vogt Sánchez EA, Arjona Padillo A, Vega Sáenz JL. Cerebelitis autoinmune en enfermedad de Crohn. Gastroenterol Hepatol. 2019. <span class="elsevierStyleInterRef" id="intr0005" href="https://doi.org/10.1016/j.gastrohep.2019.06.002">https://doi.org/10.1016/j.gastrohep.2019.06.002</span></p>" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1046 "Ancho" => 900 "Tamanyo" => 66803 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Magnetic resonance imaging of the head.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fulminant cerebellitis with radiological recurrence in an adult patient with Crohn’s disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.P. Flanagan" 1 => "A.A. Rabinstein" 2 => "N. Kumar" 3 => "K. Schroeder" 4 => "O.H. Kantarci" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jns.2013.09.017" "Revista" => array:7 [ "tituloSerie" => "J Neurol Sci" "fecha" => "2014" "volumen" => "336" "numero" => "January" "paginaInicial" => "247" "paginaFinal" => "250" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24090762" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neurologic disorders associated with inflammatory bowel disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Benavente" 1 => "G. Morís" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-1331.2010.03095.x" "Revista" => array:6 [ "tituloSerie" => "Eur J Neurol" "fecha" => "2011" "volumen" => "18" "paginaInicial" => "138" "paginaFinal" => "143" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20500801" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute cerebellar ataxia, acute cerebellitis, and opsoclonus-myoclonus syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Desai" 1 => "W.G. Mitchell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1177/0883073812450318" "Revista" => array:6 [ "tituloSerie" => "J Child Neurol" "fecha" => "2012" "volumen" => "27" "paginaInicial" => "1482" "paginaFinal" => "1488" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22805251" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fulminant cerebellitis: a fatal, clinically isolated syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Kamate" 1 => "V. Chetal" 2 => "V. Hattiholi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pediatrneurol.2009.03.018" "Revista" => array:6 [ "tituloSerie" => "Pediatr Neurol" "fecha" => "2009" "volumen" => "41" "paginaInicial" => "220" "paginaFinal" => "222" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19664542" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metabotropic glutamate receptor type 1 autoantibody-associated cerebellitis: a primary autoinmune disease?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. Marignier" 1 => "F. Chenevier" 2 => "V. Rogemond" 3 => "P. Sillevis Smitt" 4 => "C. Renoux" 5 => "G. Cavillon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archneurol.2010.51" "Revista" => array:6 [ "tituloSerie" => "Arch Neurol" "fecha" => "2010" "volumen" => "67" "paginaInicial" => "627" "paginaFinal" => "630" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20457964" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/24443824/0000004200000010/v1_201912241024/S2444382419302366/v1_201912241024/en/main.assets" "Apartado" => array:4 [ "identificador" => "77930" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Scientific letter" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/24443824/0000004200000010/v1_201912241024/S2444382419302366/v1_201912241024/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382419302366?idApp=UINPBA00004N" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 October | 45 | 10 | 55 |
2024 September | 67 | 10 | 77 |
2024 August | 51 | 15 | 66 |
2024 July | 56 | 16 | 72 |
2024 June | 36 | 7 | 43 |
2024 May | 45 | 4 | 49 |
2024 April | 31 | 6 | 37 |
2024 March | 43 | 10 | 53 |
2024 February | 39 | 5 | 44 |
2024 January | 49 | 6 | 55 |
2023 December | 43 | 3 | 46 |
2023 November | 82 | 6 | 88 |
2023 October | 71 | 9 | 80 |
2023 September | 48 | 4 | 52 |
2023 August | 63 | 4 | 67 |
2023 July | 55 | 8 | 63 |
2023 June | 62 | 5 | 67 |
2023 May | 99 | 3 | 102 |
2023 April | 78 | 1 | 79 |
2023 March | 92 | 1 | 93 |
2023 February | 81 | 7 | 88 |
2023 January | 78 | 7 | 85 |
2022 December | 93 | 12 | 105 |
2022 November | 96 | 10 | 106 |
2022 October | 64 | 8 | 72 |
2022 September | 63 | 12 | 75 |
2022 August | 62 | 8 | 70 |
2022 July | 55 | 9 | 64 |
2022 June | 57 | 10 | 67 |
2022 May | 40 | 6 | 46 |
2022 April | 50 | 6 | 56 |
2022 March | 54 | 11 | 65 |
2022 February | 80 | 7 | 87 |
2022 January | 81 | 13 | 94 |
2021 December | 53 | 4 | 57 |
2021 May | 1 | 0 | 1 |
2020 May | 2 | 0 | 2 |