metricas
covid
Buscar en
Gastroenterología y Hepatología
Toda la web
Inicio Gastroenterología y Hepatología Cocaine induced acute pancreatitis
Journal Information

Statistics

Follow this link to access the full text of the article

Cocaine induced acute pancreatitis
Pancreatitis aguda inducida por cocaína
Sergio Vázquez-Rodrígueza, Santiago Sotoa,
Corresponding author
iagosoto@hotmail.com

Autor para correspondencia. iagosoto@hotmail.com
, Estela Fernándeza, Ruth Baltara, Enrique Vázquez-Astraya
a Servicio de Aparato Digestivo, Complexo Hospitalario de Pontevedra
Read
18666
Times
was read the article
1727
Total PDF
16939
Total HTML
Share statistics
 array:19 [
  "pii" => "S0210570509003677"
  "issn" => "02105705"
  "doi" => "10.1016/j.gastrohep.2009.03.003"
  "estado" => "S300"
  "fechaPublicacion" => "2009-10-01"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Gastroenterol Hepatol. 2009;32:588-9"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 10110
    "formatos" => array:3 [
      "EPUB" => 12
      "HTML" => 9463
      "PDF" => 635
    ]
  ]
  "itemAnterior" => array:16 [
    "pii" => "S0210570509003653"
    "issn" => "02105705"
    "doi" => "10.1016/j.gastrohep.2009.03.002"
    "estado" => "S300"
    "fechaPublicacion" => "2009-10-01"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Gastroenterol Hepatol. 2009;32:587-8"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2884
      "formatos" => array:3 [
        "EPUB" => 6
        "HTML" => 2540
        "PDF" => 338
      ]
    ]
    "es" => array:9 [
      "idiomaDefecto" => true
      "titulo" => "Meningitis por <span class="elsevierStyleItalic">Listeria monocytogenes</span> durante tratamiento con adalimumab"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "587"
          "paginaFinal" => "588"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Meningitis due to <span class="elsevierStyleItalic">Listeria monocytogenes</span> during adalimumab therapy"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Cecilia Gil, Jes&#250;s Legido, Carlos Cuenca, Ana Santamar&#237;a, Mar&#237;a Victoria Sacrist&#225;n, Concepci&#243;n Salvatierra, Eugenio Fern&#225;ndez-Rubio, Julio Izquierdo"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "Cecilia"
              "apellidos" => "Gil"
            ]
            1 => array:2 [
              "nombre" => "Jes&#250;s"
              "apellidos" => "Legido"
            ]
            2 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Cuenca"
            ]
            3 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Santamar&#237;a"
            ]
            4 => array:2 [
              "nombre" => "Mar&#237;a Victoria"
              "apellidos" => "Sacrist&#225;n"
            ]
            5 => array:2 [
              "nombre" => "Concepci&#243;n"
              "apellidos" => "Salvatierra"
            ]
            6 => array:2 [
              "nombre" => "Eugenio"
              "apellidos" => "Fern&#225;ndez-Rubio"
            ]
            7 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Izquierdo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570509003653?idApp=UINPBA00004N"
    "url" => "/02105705/0000003200000008/v0_201307171023/S0210570509003653/v0_201307171025/es/main.assets"
  ]
  "en" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Cocaine induced acute pancreatitis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "588"
        "paginaFinal" => "589"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Sergio V&#225;zquez-Rodr&#237;guez, Santiago Soto, Estela Fern&#225;ndez, Ruth Baltar, Enrique V&#225;zquez-Astray"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Sergio"
            "apellidos" => "V&#225;zquez-Rodr&#237;guez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Santiago"
            "apellidos" => "Soto"
            "email" => array:1 [
              0 => "iagosoto&#64;hotmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Estela"
            "apellidos" => "Fern&#225;ndez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Ruth"
            "apellidos" => "Baltar"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Enrique"
            "apellidos" => "V&#225;zquez-Astray"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Servicio de Aparato Digestivo, Complexo Hospitalario de Pontevedra"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
            "correspondencia" => "Autor para correspondencia. iagosoto@hotmail.com"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Pancreatitis aguda inducida por coca&#237;na"
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara">Cocaine &#40;benzoylmethyl ecgonine&#41; is a crystalline tropane alkaloid that is obtained from the leaves of the coca&#46; Cocaine is an addictive illegal drug<a href="&#35;bib1" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">1</span></a>&#46; Spain has become the top consumer of cocaine in continental Europe&#44; according to a recent European Union study on drug use&#46; By a United Nations count&#44; 3&#37; of Spain&#39;s adult population consumes cocaine&#46; Specifically&#44; it is a dopamine reuptake inhibitor&#44; a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor<a href="&#35;bib2" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">2</span></a>&#46; Cocaine is a potent central nervous system stimulant&#46; Short-term cocaine effects include&#58; increased blood pressure&#44; constricted blood vessels&#44; mental alertness&#44; dilated pupils&#44; increased energy&#44; increased heart rate and temperature and decreased appetite<a href="&#35;bib3" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">3</span></a><span class="elsevierStyleSup">&#44;</span><a href="&#35;bib4" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">4</span></a>&#46;</p><p class="elsevierStylePara">Cardiovascular and neurologic are the predominant alterations&#46; Digestive complications are infrequent&#46; Pancreatic involvement is exceptional and only isolated cases have been reported<a href="&#35;bib2" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">2</span></a><span class="elsevierStyleSup">&#44;</span><a href="&#35;bib5" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">5</span></a>&#46;</p><p class="elsevierStylePara">A 21 years old boy with epilepsy treated with lamotrigine was accepted at hospital with abdominal pain radiated straight through to the back&#44; nausea and vomiting&#46; Amylase reached 1710U&#47;L&#44; lipase 2981U&#47;L&#44; LDH 2399U&#47;L&#44; Hematocrit 50&#44;2&#37;&#44; white blood cell count was 21300&#47;mm<span class="elsevierStyleSup">3</span> &#40;77&#44;4&#37; neutrophils&#41; platelets 416&#46;000&#47;mm<span class="elsevierStyleSup">3</span>&#46; Blood urea&#44; oxygen saturation&#44; serum calcium&#44; coagulation parameters and triglyceride levels were normal&#46; The patient denied alcohol ingestion or drugs consumption&#46; Serological studies for CMV&#44; EBV and HIV were negative&#46; Abdominal ultrasonography excluded gallstones and dilatation of the bile duct&#46; A spiral computed tomography with contrast performed within 48 hours showed diffuse enlargement of the pancreas with minimal ascites &#40;Grade B of Balthazar&#41;&#46; Cholangiography MRI was normal&#46; Because of these results USE and ERCP were not performed&#46;</p><p class="elsevierStylePara">Urine drugs test was positive for cocaine and the patient admitted to use insufflated cocaine as a recreational drug&#46; He had taken cocaine 48hours before abdominal pain started&#46; Alcohol consumption was ruled out&#46;</p><p class="elsevierStylePara">Clinical evolution was positive without complications and the patient was discharged within 6 days&#46; After hospitalization&#44; he has been controlled every three months during two years without new events&#46;</p><p class="elsevierStylePara">Cocaine consumption seems to be the cause of acute pancreatitis in this patient&#46; The absence of other recognized etologies&#44; the antecedent of insufflated cocaine consumption in the last 48 hours and the elevated LDH serum values made cocaine to be the cause of acute pancreatitis in this young patient&#46;</p><p class="elsevierStylePara">Cocaine consumption cause several medical problems<a href="&#35;bib6" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">6</span></a>&#46; Heart attack&#44; arrhythmias&#44; stroke and convulsions are the most frequent&#46; Psychiatric&#44; pulmonary and renal complications have been described&#46; Digestive complications are infrequent&#46; Intestinal ischemia<a href="&#35;bib9" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">9</span></a><span class="elsevierStyleSup">&#44;</span><a href="&#35;bib10" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">10</span></a>&#44; perforation<a href="&#35;bib7" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">7</span></a>&#44; retroperitoneal fibrosis&#44; gastric ulcer<a href="&#35;bib8" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">8</span></a> has been described&#46; Pancreatic involvement is exceptional and only very few cases have been reported&#46;</p><p class="elsevierStylePara">Most of acute pancreatitis are related with alcohol consumption or gallstones&#46; Pancreatic ischemia causes acute pancreatitis too&#46;</p><p class="elsevierStylePara">Cocaine blocks the presynaptic reuptake of the neutotransmitters norepinephrine and dopamine&#46; It also causes monoaminooxidases inhibition and it has a direct anticholinergic action&#46; This way alpha- adrenergic receptors are highly stimulated&#46; Activation of the sympathetic nervous system by this mechanism produces vasoconstriction and ischemia<a href="&#35;bib8" class="elsevierStyleCrossRefs"><span class="elsevierStyleSup">8</span></a>&#46;</p><p class="elsevierStylePara">Autor para correspondencia&#46; iagosoto&#64;hotmail&#46;com</p>"
    "pdfFichero" => "14v32n08a13141355pdf001.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Medical complications of cocaine abuse&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Cregler L"
                            1 => "Herbert M&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "N Eng J Med"
                        "fecha" => "1986"
                        "volumen" => "315"
                        "paginaInicial" => "1495"
                        "paginaFinal" => "1500"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Cocaine-associated acute pancreatitis&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "Macaigne G"
                            1 => "Simon P"
                            2 => "Chayette C"
                            3 => "Cheiab S"
                            4 => "Deplus R"
                            5 => "et-al&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gastroenterol Clin Biol"
                        "fecha" => "2003"
                        "volumen" => "27"
                        "paginaInicial" => "241"
                        "paginaFinal" => "242"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12658140"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Rabdomiolisis en la intoxicaci&#243;n aguda por coca&#237;na&#46;"
                      "idioma" => "es"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "Bernad M"
                            1 => "Iba&#241;ez C"
                            2 => "Medra&#241;o JC"
                            3 => "Pe&#241;a JM"
                            4 => "Mart&#237;nez A"
                            5 => "Ju&#225;rez S&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "An Med Intern"
                        "fecha" => "1990"
                        "volumen" => "7"
                        "paginaInicial" => "631"
                        "paginaFinal" => "634"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Cocaine and vasospasm&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Isner J"
                            1 => "Chokshi S"
                            2 => "L&#243;pez C&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198912073212309"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1989"
                        "volumen" => "321"
                        "paginaInicial" => "1604"
                        "paginaFinal" => "1606"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2586556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Acute pancreatitis and cocaine&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Garcia CJ"
                            1 => "Gonzalez RV"
                            2 => "Muino MA"
                            3 => "L&#243;pez C&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "An Med Intern"
                        "fecha" => "1996"
                        "volumen" => "13"
                        "paginaInicial" => "513"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Complications related with cocaine abuse that require hospital admission&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "Sope&#241;a B"
                            1 => "Rivera A"
                            2 => "Rodriguez-Dominguez M"
                            3 => "Rodr&#237;guez-Rodr&#237;guez M"
                            4 => "Argibay A"
                            5 => "Maure B"
                            6 => "et-al&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Clin Esp"
                        "fecha" => "2008"
                        "volumen" => "208"
                        "paginaInicial" => "12"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18221656"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Perforaci&#243;n de viscera hueca asociada al consumo de cocaina&#46;"
                      "idioma" => "es"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Tallon L"
                            1 => "Casado MD"
                            2 => "Lopez F"
                            3 => "Puppo AM"
                            4 => "Sousa J&#46;M&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Gastroenterol Hepatol"
                        "fecha" => "2008"
                        "volumen" => "31"
                        "paginaInicial" => "624"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19091258"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Gastrointestinal manifestations of cocaine addiction&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Gourgoutis G"
                            1 => "Das G&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Clin Pharmacol Ther"
                        "fecha" => "1994"
                        "volumen" => "32"
                        "paginaInicial" => "136"
                        "paginaFinal" => "141"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8205375"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Cocaine abuse and intestinal ischemia&#58; case report and literature review&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Ruiz M"
                            1 => "Cata T"
                            2 => "Moll JL"
                            3 => "Pueyto J&#46;M&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cir Esp"
                        "fecha" => "2003"
                        "volumen" => "73"
                        "paginaInicial" => "136"
                        "paginaFinal" => "137"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:3 [
                      "titulo" => "Superior mesenteric and celiac trunk ischemia alter administration of cocaine&#46;"
                      "idioma" => "en"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "Priego P"
                            1 => "Rodriguez G"
                            2 => "Galindo J"
                            3 => "Garcia D"
                            4 => "Losa N"
                            5 => "Caba&#241;as J"
                            6 => "et-al&#46; &#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Esp Enf Dig"
                        "fecha" => "2006"
                        "volumen" => "98"
                        "paginaInicial" => "964"
                        "paginaFinal" => "968"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/02105705/0000003200000008/v0_201307171023/S0210570509003677/v0_201307171025/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "15966"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Cartas al director"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/02105705/0000003200000008/v0_201307171023/S0210570509003677/v0_201307171025/en/14v32n08a13141355pdf001.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570509003677?idApp=UINPBA00004N"
]
Article information
ISSN: 02105705
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 October 150 15 165
2024 September 131 16 147
2024 August 194 15 209
2024 July 189 8 197
2024 June 135 9 144
2024 May 117 10 127
2024 April 120 15 135
2024 March 114 17 131
2024 February 104 15 119
2024 January 144 17 161
2023 December 133 21 154
2023 November 121 33 154
2023 October 152 19 171
2023 September 161 13 174
2023 August 153 23 176
2023 July 184 20 204
2023 June 141 18 159
2023 May 107 13 120
2023 April 89 2 91
2023 March 109 14 123
2023 February 80 16 96
2023 January 66 58 124
2022 December 55 26 81
2022 November 94 35 129
2022 October 114 31 145
2022 September 101 17 118
2022 August 108 13 121
2022 July 81 9 90
2022 June 88 16 104
2022 May 99 27 126
2022 April 108 21 129
2022 March 129 23 152
2022 February 80 16 96
2022 January 103 14 117
2021 December 114 17 131
2021 November 123 16 139
2021 October 126 12 138
2021 September 104 17 121
2021 August 88 14 102
2021 July 97 11 108
2021 June 143 17 160
2021 May 135 19 154
2021 April 360 25 385
2021 March 171 22 193
2021 February 143 16 159
2021 January 162 29 191
2020 December 156 10 166
2020 November 149 9 158
2020 October 108 15 123
2020 September 170 41 211
2020 August 176 33 209
2020 July 160 19 179
2020 June 163 27 190
2020 May 153 20 173
2020 April 148 15 163
2020 March 187 28 215
2020 February 187 34 221
2020 January 212 12 224
2019 December 161 28 189
2019 November 161 18 179
2019 October 140 14 154
2019 September 154 19 173
2019 August 127 31 158
2019 July 123 35 158
2019 June 146 22 168
2019 May 251 34 285
2019 April 163 31 194
2019 March 72 5 77
2019 February 98 13 111
2019 January 85 7 92
2018 December 69 4 73
2018 November 64 3 67
2018 October 52 3 55
2018 September 41 5 46
2018 August 26 0 26
2018 July 42 6 48
2018 June 35 1 36
2018 May 37 1 38
2018 April 94 3 97
2018 March 79 1 80
2018 February 45 0 45
2018 January 48 1 49
2017 December 57 1 58
2017 November 56 1 57
2017 October 67 5 72
2017 September 63 2 65
2017 August 64 2 66
2017 July 88 3 91
2017 June 143 6 149
2017 May 146 6 152
2017 April 79 2 81
2017 March 99 31 130
2017 February 104 1 105
2017 January 83 2 85
2016 December 79 9 88
2016 November 62 7 69
2016 October 99 8 107
2016 September 109 9 118
2016 August 76 5 81
2016 July 65 8 73
2016 June 70 8 78
2016 May 47 13 60
2016 April 55 25 80
2016 March 46 13 59
2016 February 41 13 54
2016 January 30 10 40
2015 December 35 11 46
2015 November 56 10 66
2015 October 42 12 54
2015 September 46 4 50
2015 August 52 7 59
2015 July 62 5 67
2015 June 38 2 40
2015 May 48 2 50
2015 April 78 6 84
2015 March 69 12 81
2015 February 40 3 43
2015 January 38 6 44
2014 December 71 4 75
2014 November 57 6 63
2014 October 62 5 67
2014 September 78 2 80
2014 August 86 3 89
2014 July 52 2 54
2014 June 43 1 44
2014 May 46 2 48
2014 April 45 2 47
2014 March 43 4 47
2014 February 42 3 45
2014 January 41 2 43
2013 December 47 2 49
2013 November 84 5 89
2013 October 138 3 141
2013 September 114 3 117
2013 August 126 6 132
2013 July 99 4 103
2009 September 3131 0 3131
Show all

Follow this link to access the full text of the article

es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos