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2016 FI

© Thomson Reuters, Journal Citation Reports, 2016

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  • Impact Factor: 1.439 (2016)
  • SCImago Journal Rank (SJR):0,38
  • Source Normalized Impact per Paper (SNIP):0,591

© Thomson Reuters, Journal Citation Reports, 2016

Allergol Immunopathol (Madr) 2014;42:539-43 - DOI: 10.1016/j.aller.2014.06.003
Original Article
Can early skin care normalise dry skin and possibly prevent atopic eczema? A pilot study in young infants
B.K. Kvenshagena,, , K.-H. Carlsenb,c, P. Mowinckelc, T.L. Berentsb,d, K.C.L. Carlsenc,b
a Department of Paediatrics, Oestfold Hospital Trust, Fredrikstad, Norway
b Faculty of Medicine, University of Oslo, Oslo, Norway
c Department of Paediatrics, Oslo University Hospital, Oslo, Norway
d Department of Dermatology, Oslo University Hospital, Oslo, Norway
Received 02 March 2014, Accepted 08 June 2014

Atopic eczema (AE) affects approximately 20% of children in Northern countries. Onset during early infancy is common and is characterised by altered skin barrier, increased water loss and defective lipid layer. Restoration of skin barrier by emollients and/or oil baths is an important part of AE treatment, but its role in preventing xerosis and AE is unknown.

The present pilot study aimed to assess if xerosis, and possibly AE, could be reduced at six months of age by early introduction of frequent oil baths/facial fat cream in infants with dry skin.


A controlled intervention pilot study included 56 six-week-old infants with xerosis, but not AE. Skin quality score ranging from 0 (normal skin) to 4 (probable AE), was assessed at inclusion, three and six months of age, with skin quality at six months as main outcome. One well baby clinic was recruited for intervention, frequent skin care (oil bath (0.5dl) and facial fat cream, five well baby clinics recruited for observation only.


The intervention group (n=24) had more often normal skin (75%) at six months than the observation group (37.5%) (p<0.001), and less often probable AE (4.0 vs. 19.0%, respectively, ns). Oil baths were performed regularly, 2–4 up to 5–7 times/week in the intervention group, vs. fewer oil baths with sparse volume of oil in the observation group. No adverse reactions were reported.


Regular oil baths in infants seem to reduce xerosis and may possibly reduce atopic eczema.

Atopic dermatitis, Infants, Skin barrier, Skin care, Xerosis
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