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Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Risk stratification of coronary artery disease using radionuclides. Current stat...
Journal Information
Vol. 36. Issue 6.
Pages 377-387 (November - December 2017)
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6
Vol. 36. Issue 6.
Pages 377-387 (November - December 2017)
Special collaboration
Risk stratification of coronary artery disease using radionuclides. Current status of clinical practice
Estratificación de riesgo de enfermedad coronaria con métodos isotópicos. Estado actual de la práctica clínica
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6
T. Massardo
Corresponding author
tmassardo@hcuch.cl

Corresponding author.
, L. Alarcón, J. Spuler
Sección Medicina Nuclear, Departamento Medicina, Hospital Clínico Universidad de Chile, Santiago, Chile
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Table 1. Performance of myocardial perfusion PET and SPECT in the evaluation of coronary artery disease.
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Table 2. Dosimetry according to radiotracers of myocardial perfusion with SPECT and PET techniques.
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Abstract

A discussion is presented on the current use of radionuclides for evaluation of coronary artery disease in relation to other available techniques. The review is focused on coronary artery disease risk stratification employing single photon emission computed tomography and positron emission tomography, as well as on ischemic cardiomyopathy and myocardial viability applications.

Concepts are presented regarding coronary blood flow reserve, diagnostic and prognostic values, criteria for its appropriate use, as well as current methods to reduce unnecessary patient irradiation, in order to optimize nuclear cardiology practice.

Keywords:
Coronary artery disease
Risk stratification
Cardiac SPECT
Cardiac PET
Cardiovascular risk factor
Resumen

Se discute el uso actual de los radioisótopos para la evaluación de la enfermedad coronaria con relación a otras técnicas disponibles. La revisión se centra en la estratificación de riesgo de enfermedad coronaria mediante tomografía de fotón único y de doble fotón, y su la aplicación en viabilidad miocárdica y miocardiopatía isquémica.

Se presentan conceptos sobre flujo absoluto y reserva de flujo coronario, valor diagnóstico y pronóstico, así como criterios de uso apropiados de las pruebas y también los métodos actuales para disminuir la radiación innecesaria de los pacientes, optimizando la práctica de la cardiología nuclear.

Palabras clave:
Enfermedad coronaria
Estratificación de riesgo
SPECT cardíaco
PET cardíaco
Factor de riesgo cardiovascular

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