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Inicio Revista Colombiana de Reumatología Correlación y concordancia de la autoclinimetría en artritis reumatoide: revis...
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Vol. 20. Núm. 1.
Páginas 30-57 (Marzo 2013)
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Vol. 20. Núm. 1.
Páginas 30-57 (Marzo 2013)
Acceso a texto completo
Correlación y concordancia de la autoclinimetría en artritis reumatoide: revisión sistemática de la literatura y metanálisis
Patients-reported outcomes correlation and concordance in rheumatoid arthritis: systematic literature review and metaanalysis
Visitas
4859
Jenny Amaya-Amaya1, Gloria Torralvo-Morato1, Omar-Javier Calixto2, Rolando Calderón-Rojas2, Julián Caro-Moreno2, Aura-María Domínguez3, Rubén-Darío Mantilla1,3, Juan-Manuel Anaya1, Adriana Rojas-Villarraga1,
Autor para correspondencia
adrirojas@gmail.com

Correspondencia.
1 Centro de Estudio de Enfermedades Autoinmunes (CREA). Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia
2 Semillero de Investigación CREA. Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, Colombia
3 Riesgo de Fractura, CAYRE IPS, Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, Colombia
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Resumen
Introducción

Existe un interés mundial en la evaluación de la artritis reumatoide (AR) desde la perspectiva del paciente mediante la autoclinimetría [en inglés patient-reported out comes (PROs)], que busca evaluar la actividad de la enfermedad, calidad de vida, pronóstico y adherencia terapéutica.

Objetivo

Evaluar y analizar de manera objetiva el grado de correlación o concordancia entre las herramientas de autoclinimetría implementadas en AR con las mediciones objetivas realizadas por el equipo de salud, a través de una revisión sistemática de la literatura mundial y metanálisis.

Materiales y métodos

Se realizó revisión sistemática de la literatura acerca de autoclinimetría en AR en PubMed, LILACS, Embase, SciELO y Biblioteca Virtual de la Salud, utilizando términos MeSH y DeCS, con un solo limite utilizado: humanos. Posteriormente, se realizó el metanálisis utilizando el programa Comprehensive Meta-Analysis versión 2.

Resultados

Se incluyeron 85 artículos, demostrando correlaciones de moderadas a altas, entre las medidas objetivas realizadas por profesionales de la salud [DAS28, CDAI, SDAI, conteo articular inflamatorio (CAI) y doloroso (CAD), entre otros],y de autoclinimetría (RAPIDs, RADAI, RADAR, HAQ y CAI y CAD), por medio de metanálisis utilizando modelo de efectos aleatorios (p<0.0001).

Conclusiones

La autoclinimetría tiene correlación y concordancia adecuadas con las medidas objetivas realizadas por el médico y su equipo entrenado. Ésta puede ser administrada tanto en la práctica clínica cotidiana como en ensayos clínicos, sin pretender que remplace el juicio clínico, pero con el ánimo de facilitar y optimizar el tiempo de consulta y los desenlaces de los pacientes.

Palabras clave:
Autoclinimetría
clinimetría
artritis reumatoide
Summary
Introduction

There is a worldwide interest about the evaluation of rheumatoid arthritis (RA) from the perspective of the patient, using patient-reported outcomes (PROs), in order to assess disease activity, quality of life, prognosis, and treatment adherence.

Objective

To evaluate and analyze the instruments of PROs and the degree of correlation with the objective measures done by the health practitioners through a systematic review and metaanalysis.

Materials and methods

A systematic review was done in PubMed, LILACS, Embase, SciELO y Virtual Library Health (Biblioteca Virtual de la Salud) databases, using the MeSH terms and DeCS, with limit: Humans. A metaanalysis was done using the software Comprehensive Meta-Analysis version 2.

Results

85 articles were included, finding high to moderate correlations between the objective measures performed by trained health care practitioners [DAS28, CDAI, SDAI, swollen joint count (SJC) and tender joint count (TJC) among others] and PROs (RAPIDs, RADAI, RADAR, HAQ, SJC and TJC) through metaanalysis applying the random effect models (p<0.0001).

Conclusions

PROs have an adequate correlation and concordance with the objective measures done by the health care practitioners. It can be administrated in the clinical practice and clinical trials, without pretending to replace the clinical concept but with the aim to facilitate and optimize the clinical consult and the patient outcomes.

Key words:
Patient-reported outcomes
clinical assessment
rheumatoid arthritis
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