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Inicio Revista Colombiana de Reumatología Calcifying Lupus panniculitis in a patient without manifestations of systemic lu...
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Vol. 18. Núm. 2.
Páginas 140-145 (Junio 2011)
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Vol. 18. Núm. 2.
Páginas 140-145 (Junio 2011)
DOI: 10.1016/S0121-8123(11)70129-3
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Calcifying Lupus panniculitis in a patient without manifestations of systemic lupus Erythematosus
Lupus paniculitis calcificante en un paciente sin manifestaciones del lupus eritematoso sistémico
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Yimy F. Medina1,
Autor para correspondencia
yimym@yahoo.com

Correspondencia.
, Mariam Rolon2, Antonio Iglesias1
1 Rheumatology Unit, Internal Medicine Department. Universidad Nacional de Colombia
2 Dermatopathologist
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Summary

Lupus panniculitis or lupus profundus is a variant of lupus Erythematosus cutaneous that primarily affects subcutaneous tissue. Clinically, it is characterized by one or several firm subcutaneous nodules and/or plaques with or without overlying epidermal changes. It is reported to occur with a frequency of 2–3% in patients with Systemic Lupus Erythematosus (SLE). Between 10 and 50 percent of patients with lupus panniculitis will have or eventually develop Systemic Lupus Erythematosus. In nearly all cases there are deep, erythematosus plaques and nodules, and some of them ulcers, which usually involve the proximal extremities, trunk, breasts, buttocks, and face. These lesions may be tender and painful and frequently heal with atrophy and scaring, turning as a chronic condition and subsequently heal with disfigurement. We describe a patient who suffers from lupus panniculitis with no association to SLE symptoms and complicated by several progressive and disabling cutaneous lesions.

Key words:
lupus panniculitis
dystrophic calcification
lupus erythematosus cutaneous
Resumen

La paniculitis lupica o también llamada lupus profundus es una variante del lupus eritematosos cutáneo que afecta el tejido celular subcutáneo. Se carartetiza clínicamente por uno o varios nódulos subcutáneos que son firmes y/o placa con osin cambios epidérmicos. Se ha informado su frecuencia en 2% a 3% de casos de Lupus eritematoso sistémico. Entre 10 a 50% de los casos de paniculitis lupica va a desarrollar lupus eritematosos sistémico. En casi todos los casos hay placas eritematosas y/o nódulos que algunos se ulceran y que usualmente estna localizados en las áreas proximales de las extremidades, tronco,mamas, nalgas y la cara. Estas lesiones pueden ser clínicamente dolorosas y sensibles a la presión y frecuentemente cicatrizan con desfiguración del área circundante. Describimos un paciente que padece de paniculitis lupica sin asociación de lupus eritematoso sistémico y que se complico con varias lesiones cutáneas progresivas y discapacitantes.

Palabras clave:
paniculitis lúpica
calcificación distrófica
lupus eritematoso cutáneo
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References
[1.]
J.A. Yell, J. Mbuagbaw, S.M. Burge.
Cutaneous manifestations of systemic lupus erythematosus.
Br J Dermatol, 135 (1996), pp. 355-362
[2.]
E. Diaz-Jouanen, R.J. DeHoratius, D. Alarcon-Segovia, R.P. Messner.
Systemic lupus erythematosus presenting as panniculitis (lupus profundus).
Ann Intern Med, 82 (1975), pp. 376-382
[3.]
D.L. Tuffanelli.
Lupus erythematosus (panniculitis) profundus: a classic revisited commentary and report of 22 cases.
Hawaii Med J, 41 (1982), pp. 394-397
[4.]
P.B. Martens, K.G. Moder, I. Ahmed.
Lupus panniculitis: clinical perspectives from a case series.
J Rheumatol, 26 (1999), pp. 68-72
[5.]
M. Fuchtenbusch, A. Vogel, P. Achenbach, M. Gummer, A.G. Ziegler, E. Albert, et al.
Lupus-like panniculitis in a patient with autoimmune polyendocrinopathycandidiasisectodermal dystrophy (APECED).
Exp Clin Endocrinol Diabetes, 111 (2003), pp. 288-293
[6.]
C. Diaz Cascajo.
Panniculitis Definition of Terms and Diagnostic Strategy.
Am J Dermatopathol, 22 (2000), pp. 530-549
[7.]
Kren O, op. cit., O. Kren, “lupus erythematosus” in Arch Dermatol u syph 1912;112:391–394
[8.]
Oppenheim M, 1915, op cit., M. Oppenheim, Lupus erythematosus Profundus”, in Arch Dermatol u syph, 1912–1913;115:847
[11.]
A. Iglesias.
Las manifestaciones dermatológicas del lupus eritematoso.
Historia del Lupus, Panamericana Press, (2003),
[10.]
E. Lipskeir, M. Weizenbluth.
Calcinosis circumscripta: indications for surgery.
Bull Hosp Jt Dis Orthop, 49 (1989), pp. 75-84
[11.]
J. Callen.
Cutaneous lupus erythematosus: A personal approach to management.
Australasian Journal of Dermatology, 47 (2006), pp. 13-27
[12.]
N.P. Sanchez, M.S. Peters, R.K. Winkelmann.
The histopathology of lupus erythematosus panniculitis.
J Am Acad Dermatol, 5 (1981), pp. 673-680
[13.]
R.K. Winkelmann, M.S. Peters.
“Lupus Panniculitis” In dermatology update, reviews for physicians.
Elsevier S. Moschella, (1982),
[14.]
M.S. Peters, W.P. Su.
Lupus erythematosus panniculitis.
Med Clin North Am, 73 (1989), pp. 1113-1126
[15.]
J.L. Diaz-Ramon, R. Izu, J.M. Vicente, J. Mitxelena, A. Aguirre, X. Eizaguirre, J.L. Diaz- Perez.
The Histopathological Spectrum of Lupus Panniculitis.
Am J Dermatopathol, 20 (1998), pp. 614
[16.]
D. Wright.
Lupus panniculitis.
Ann Rheum Dis, 56 (1997), pp. 77-78
[17.]
H.C. Nossent, T.J.G. Swatak, J.H.M. Berden.
Systemic lupus erythematosus: analysis of disease activity in 55 patients with endstage renal failure treated with hemodialysis or continuous ambulatory peritoncal dialysis.
Am J Med, 89 (1990), pp. 169-174
[18.]
S.C. Thoong, K.H. Stenzel.
End stage renal disease in systemic lupus erythematosus profundus.
Clin Exp Dermatol, 14 (1989), pp. 333
[19.]
F.P. Quismoro, E.L. Dubois, S.B. Chandor.
Soft-tissue calcification in systemic lupus erythematosus.
Arch Dermatol, 111 (1975), pp. 352-356
[20.]
W.M. Kelli, J. Callen.
Calcifying Lupus Panniculitis in a Patient with Subacute Cutaneous Lupus Erythematosus: Response to Diltiazem and Chloroquine.
The Journal of Rheumatology, 28 (2001), pp. 9
[21.]
C. Thurson, A. Curtis.
Lupus Erythematosus Profundus (Kaposi-Irgang): Clinical Response to Hydroxychloroquine Sulphate.
Arch Dermatol, 93 (1966), pp. 557
[22.]
D.L. Tuffanelli.
Management of cutaneous lupus erythematosus.
Clin Dermatol, 3 (1985), pp. 123-130
[23.]
N.P. Burrows, M.J. Walport, A.h. Hammond, N. Davey, R.R. Jones.
Lupus erythematosus profundus with partial C4 deficiency responding to thalidomide.
Br J Dermatol, 125 (1991), pp. 62-67
[24.]
D. Fuchs, L. Fruchter, B. Fishel, M. Holtzman, M. Yaron.
Colchicine suppression of local inflammation due to calcinosis in dermatomyositis and progressive systemic sclerosis.
Clin Rheumatol, 5 (1986), pp. 527-530
[25.]
H.-S. Chung, S.-K. Hann.
Lupus panniculitis treated by a combination therapy of hydroxychloroquine and quinacrine.
J Dermatol, 24 (1997), pp. 69
[26.]
E. Skuterud, O.A. Sydnes, T.K. Haavik.
Calcinosis in dermatomyositis treated with probenecid.
Scand J Rheumatol, 10 (1981), pp. 92-94
[27.]
R.G. Berget, G.L. Featherstone, R.H. Raasch, W.H. McCarthey, N.M. Hadler.
Treatment of calcinosis universalis with low-dose warfarin.
Am J Med, 83 (1987), pp. 72-76
[28.]
S. Yoshida, K. Torikai.
The effects of warfarin on calcinosis in a patients with systemic sclerosis.
J Rheumatol, 20 (1993), pp. 1233-1235
[29.]
M.J. Farah, G.m. Palmieri, J.I. Sebes, M.A. Cremer, J.D. Massie, R.S. Pinals.
The effects of diltiazem on calcinosis in a patient with the CREST syndrome.
Arthritis Rheum, 33 (1990), pp. 1287-1293
[30.]
M. Vayssairat, D. Hidouche, N. Abdoucheli-Baudot, J.P. Gaitz.
Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does ditiazem induce its regression?.
Ann Rheum Dis, 57 (1998), pp. 252-254
[31.]
S.S. Lee, J. Felsenstein, F.R. Tanzer.
Calcinosis cutis circumscrpta: treatment with intralesional corticosteroid.
Arch Dermatol, 114 (1978), pp. 1080-1081
[32.]
E. Lipskeir, M. Weizenbluth.
Calcinosis circumscripta: indications for surgery.
Bull Hosp Jt Dis Orthop, 49 (1989), pp. 75-84
[33.]
P. Nogueira, C. Giuliani, N. Rey, M. Said, P. Cochat.
Calcifying panniculitis in a child after renal transplantation.
Nephrology Dial Transplant, 12 (1997), pp. 216-218
[34.]
C. Ming-Tien, C. Kuo-Su, C. Ming-Jing, L. Ning, T. Chi-Jen, Y. Rur-Sheng, C. Wen-Jin.
Lupus profundus (panniculitis) in a chronic haemodialysis patienr.
Nephrol Dial Transplant, 14 (1999), pp. 966-968
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