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Inicio Revista Colombiana de Reumatología Calcifying Lupus panniculitis in a patient without manifestations of systemic lu...
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Vol. 18. Núm. 2.
Páginas 140-145 (Junio 2011)
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Vol. 18. Núm. 2.
Páginas 140-145 (Junio 2011)
DOI: 10.1016/S0121-8123(11)70129-3
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Calcifying Lupus panniculitis in a patient without manifestations of systemic lupus Erythematosus
Lupus paniculitis calcificante en un paciente sin manifestaciones del lupus eritematoso sistémico
Yimy F. Medina1,
Autor para correspondencia

, Mariam Rolon2, Antonio Iglesias1
1 Rheumatology Unit, Internal Medicine Department. Universidad Nacional de Colombia
2 Dermatopathologist
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Lupus panniculitis or lupus profundus is a variant of lupus Erythematosus cutaneous that primarily affects subcutaneous tissue. Clinically, it is characterized by one or several firm subcutaneous nodules and/or plaques with or without overlying epidermal changes. It is reported to occur with a frequency of 2–3% in patients with Systemic Lupus Erythematosus (SLE). Between 10 and 50 percent of patients with lupus panniculitis will have or eventually develop Systemic Lupus Erythematosus. In nearly all cases there are deep, erythematosus plaques and nodules, and some of them ulcers, which usually involve the proximal extremities, trunk, breasts, buttocks, and face. These lesions may be tender and painful and frequently heal with atrophy and scaring, turning as a chronic condition and subsequently heal with disfigurement. We describe a patient who suffers from lupus panniculitis with no association to SLE symptoms and complicated by several progressive and disabling cutaneous lesions.

Key words:
lupus panniculitis
dystrophic calcification
lupus erythematosus cutaneous

La paniculitis lupica o también llamada lupus profundus es una variante del lupus eritematosos cutáneo que afecta el tejido celular subcutáneo. Se carartetiza clínicamente por uno o varios nódulos subcutáneos que son firmes y/o placa con osin cambios epidérmicos. Se ha informado su frecuencia en 2% a 3% de casos de Lupus eritematoso sistémico. Entre 10 a 50% de los casos de paniculitis lupica va a desarrollar lupus eritematosos sistémico. En casi todos los casos hay placas eritematosas y/o nódulos que algunos se ulceran y que usualmente estna localizados en las áreas proximales de las extremidades, tronco,mamas, nalgas y la cara. Estas lesiones pueden ser clínicamente dolorosas y sensibles a la presión y frecuentemente cicatrizan con desfiguración del área circundante. Describimos un paciente que padece de paniculitis lupica sin asociación de lupus eritematoso sistémico y que se complico con varias lesiones cutáneas progresivas y discapacitantes.

Palabras clave:
paniculitis lúpica
calcificación distrófica
lupus eritematoso cutáneo
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