Original
From premorbid adjustment dimensions to clinical outcomes: Exploring environmental stress and epigenetic influences on first-episode schizophrenia phenotypes
Anaid Pérez-Ramosa,b,c,d,1, Àlex Gonzalez-Segurae,1, Laura Juliàc, Clemente García-Rizoa,b,c,f,∗∗, Ana Sánchez-Torresg,h, Vito Cavonea,i, Iñaki Zorrillaa,j, Anna Manéa,k, Roberto Rodriguez-Jimeneza,l,m, Alexandra Roldana,n, Edith Pomarol-Cloteta,o, Angela Ibañeza,p, Judith Usalla,q,r, Antonio Loboa,s, Miquel Bioquea,b,c,f, Miquel Bernardob,c,t, Manuel J. Cuestah,u, Mara Parelladaa,i, Ana González-Pintoa,j, Esther Berrocosoa,d,v..., Silvia Amorettia,e,w,3, Gisela Mezquidaa,b,c,x,3,*
, the 2EPs Working Group 2Ver más
Corresponding author
a Centre for Biomedical Research in Mental Health (CIBERSAM), ISCI-III, Madrid, Spain
b Barcelona Clínic Schizophrenia Unit (BCSU), Neuroscience Institute, Hospital Clínic of Barcelona, Barcelona, Spain
c Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
d Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cadiz, Cadiz, Spain
e Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona, Barcelona, Spain
f Department of Medicine, University of Barcelona, Barcelona, Spain
g Department of Health Sciences, Universidad Pública de Navarra, Pamplona, Spain
h Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain
i Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, Madrid, Spain
j BIOARABA, Department of Psychiatry, Hospital Universitario de Alava, UPV/EHU, Vitoria, Spain
k Grup MERITT, Institut de Recerca Sant Joan de Déu, Parc Sanitari Sant Joan de Déu, Barcelona, Spain
l Universidad Complutense de Madrid (UCM), Spain
m Department of Psychiatry, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain
n Psychiatry Department, Hospital de la Santa Creu i Sant Pau, IIB SANT PAU, Barcelona, Spain
o FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain
p Department of Psychiatry, Hospital Universitario Ramon y Cajal, Universidad de Alcala, Instituto Ramon y Cajal de Investigacion Sanitaria (IRYCIS), Madrid, Spain
q Etiopatogènia i tractament dels trastorns mentals greus (MERITT), Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain
r Parc Sanitari Sant Joan de Déu, Doctor Antoni Pujadas, Sant Boi de Llobregat, Spain
s Department of Medicine and Psychiatry, Universidad de Zaragoza, Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain
t Emeritus Consultant, Barcelona Clínic Schizophrenia Unit, Hospital Clínic of Barcelona, Barcelona, Spain
u Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain
v Biomedical Research and Innovation Institute of Cadiz (INiBICA), Research Unit, Puerta del Mar University Hospital, Cádiz, Spain
w Group of Psychiatry, Mental Health and Addictions, Vall d’Hebron Research Institute (VHIR), Barcelona, Spain
x Serra-Hunter Lecturer Fellow, Department of Clinical Foundations, Pharmacology Unit, University of Barcelona, Barcelona, Spain
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