Buscar en
Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Toda la web
Inicio Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial Papel da Porphyromonas Gingivalis na Doença Periodontal
Journal Information
Vol. 48. Issue 3.
Pages 167-171 (July - September 2007)
Share
Share
Download PDF
More article options
Vol. 48. Issue 3.
Pages 167-171 (July - September 2007)
Revisão
Open Access
Papel da Porphyromonas Gingivalis na Doença Periodontal
Visits
11262
Carlos Carvalho*, Cristina Trigo Cabral**
* Médico Dentista, Aluno do Mestrado de Periodontologia no ISCN-N; Professor no ISAVE
** Médica Dentista, Professora Auxiliar no ISCS-N
This item has received

Under a Creative Commons license
Article information
Abstract
Bibliography
Download PDF
Statistics
Resumo

Porphyromonas gingivalis é uma bactéria anaeróbia estrita presente em diversas formas de doença periodontal. A sua patogenicidade está dependente de factores de virulência tais como fímbrias, lipopolissacarídeo, produção de toxinas entre outros, que levam à colonização da placa subgengival com consequente invasão e destruição dos tecidos.

Na última década, vários têm sido os trabalhos de investigação desenvolvidos no sentido de avaliar a importância deste microrganismo na doença periodontal, bem como o interesse do diagnóstico microbiológico na sua identificação.

Este trabalho tem como objectivo a revisão das características desta bactéria que a tornam um potencial patogénico periodontal, focando a etiopatogenia, mecanismos de infecção, modos de transmissão e diagnóstico microbiológico. A metodologia utilizada foi uma revisão bibliográfica dos últimos 20 anos, de revistas indexadas como por exemplo Periodontology 2000, Journal of Clinical Periodontology e Oral Microbiology Immunology.

Palavras-Chave:
Porphyromonas gingivalis
doença periodontal
factores de virulência
transmissão
Abstract

Porphyromonas gingivalis is an anaerobic strict bacteria present in diverse forms of periodontal disease. Its pathogenicity is dependent on virulence factors such as fimbriae, lypopolysaccharide, toxin production among others, that take to the colonization of the subgingival biofilm, with consequent tissue invasion and destruction. In the last decade, many have been the works developed in a way to evaluate the importance of this micro organism in periodontal disease, as well as the interest of the microbiological diagnosis in its identification.

This paper has the aim to make a revision of the characteristics of this bacteria that make her as a potential periodontal pathogenic, focusing on its etiopathogenicity, mechanisms of infection, ways of transmission and microbiological diagnosis.

The methodology used was a bibliographical revision of the last 20 years, of indexed magazines as for example Periodontology 2000, Journal of Clinical Periodontology and Oral Microbiology Immunology.

Key-words:
Porphyromonas gingivalis
periodontal disease
virulence factors
transmission
Full text is only aviable in PDF
Bibliografia
[1-]
C. Kortsik, A. Elmer, I. Tamm.
Pleural effusion due to Histoplasma capsulatum and idiophatic CD14 lymphocytopenia.
Respiration, 70 (2003), pp. 118-122
[2-]
J.W. Smalley, A.J. Birss, R. Withnall, J. Silver.
Interactions of Porphyromonas gingivalis with oxyhaemoglobin and deoxyhaemoglobin.
Biochem J, 362 (2002), pp. 239-241
[3-]
W.E. Moore, L.V. Moore.
The bacteria of periodontal diseases.
Periodontol, 5 (1994), pp. 66-77
[4-]
H.N. Newman.
Plaque and chronic inflammatory periodontal disease. A question of ecology.
J Clin Periodontol, 17 (1990), pp. 533-541
[5-]
R.J. Lamont, H.F. Jenkinson.
Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis.
Microbiol Mol Biol, 62 (1998), pp. 1244-1263
[6-]
J.L. Dzink, S.S. Socransky, A.D. Haffajee.
The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases.
J Clin Periodontol, 15 (1988), pp. 316-323
[7-]
S.S. Socransky, A.D. Haffajee.
Dental biofilms: difficult therapeutic targets.
Periodontology, 28 (2002), pp. 12-55
[8-]
V.L. Haraszthy, J.J. Zambon, M. Trevisan, M. Zeid, R.J. Genco.
Identification of periodontal pathogens in the atheromatous plaques.
J Clin Periodontol, 71 (2000), pp. 1554-1560
[9-]
C. Ménard, C. Mouton.
Clonal diversity of the taxon Porphyromonas gingivalis assessed by random amplified polymorphic DNA fingerprinting.
Infection and Immunity, 63 (1995), pp. 2522-2531
[10-]
A.J. Van winkelhoff, U. Van der Velden, E.G. Winkel, J. de Graff.
Black-pigmented Bacteroides and motile organisms in individuals with and without periodontal breakdown.
J Periodont Res, 21 (1986), pp. 434-438
[11-]
T.J. Van Steenbergen, M.D. Petit, L.H. Scholte, U. van der Welden, J. de Graff.
Transmission of Porphyromonas gingivalis between spouses.
J Clin Periodontol, 20 (1993), pp. 340-345
[12-]
P.A. Goulbourne, R.P. Ellen.
Evidence that Porphyromonas gingivalis fimbriae function in adhesion to Actinomyces viscosus.
J Bacteriol, 173 (1991), pp. 5266-5274
[13-]
S.C. Holt, L. Keasavalu, S. Walker, C.A. Genco.
Virulence factors of Porphyromonas gingivalis.
Periodontol, 20 (1999), pp. 168-238
[14-]
Holt Stanley C., Ebersole Jeffrey L..
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the “red complex”, a protype polybacterial pathogenic consortium in periodontitis.
Periodontol, 38 (2005), pp. 72-122
[15-]
S. Hamada, T. Fujiwara, S. Morishima, I. Takahashi, I. Nakagawa, S. Kimura, T. Ogawa.
Molecular and immunological characterization of the fimbriae of Porphyromonas gingivalis.
Microbiol Immunol, 38 (1994), pp. 921-930
[16-]
A. Amano, T. Fujiwara, H. Nagata, M. Kubowira, A. Sharma, H.T. Sojar, R.J. Genco, S. Hamada, S. Shizukuishi.
Porphyromonas gingivalis fimbriae mediate coaggregation with Streptococcus oralis through specific domains.
J Dent Res, 76 (1997), pp. 852-857
[17-]
R.J. Lamont, H.I. Jenkinson.
Subgingival colonization by Porphyromonas gingivalis.
Oral Microbiol Immunol, 15 (2000), pp. 341-349
[18-]
Proteases of Porphyromonas gingivalis: What they don't do? Oral Microbiol Immunol 1998; 13: 263–270.
[19-]
M. Tuite-Mcdonnel, A.L. Griffen, M.L. Moeschberger, R.E. Dalton, P.A. Fuerst, E.J. Leys.
Concordance of Porphyromonas gingivalis colonization in families.
J Clin Microbiol, 35 (1997), pp. 455-461
[20-]
S. Asikainen, C. Chen, J. Slots.
Likelihood of transmitting Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in families with periodontitis.
Oral Microbiol Immunol, 11 (1996), pp. 387-394
[21-]
B. Von Troil-Linden, H. Torkko, S. Alaluusua, J. Wolf, H. Jousimies-Somer, S. Asikainen.
Periodontal findings in spouses. A clinical, radiographic and microbiological study.
J Clin Periodontol, 22 (1995), pp. 93-99
[22-]
B. Von Troil-Linden, H. Torkko, S. Alaluusua, H. Jousimies-Somer, S. Asikainen.
Salivary levels of suspected periodontal pathogens in relation to periodontal status and treatment.
J Dent, 74 (1995), pp. 1789-1795
[23-]
J. Slots.
Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontal disease: introduction.
Periodontol, 20 (1999), pp. 7-13
[24-]
C. Chen, J. Slots.
Microbiological tests for Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis.
Periodontol, 20 (1999), pp. 53-64
[25-]
J. Slots, Ting Miriam.
Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment.
Periodontol, 20 (1999), pp. 82-121

(Carvalho C, Cabral CT. Papel da Porphyromonas Gingivalis na Doença Periodontal. Rev Port Estomatol Cir Maxilofac 2007;48:167–171)

Copyright © 2007. Sociedade Portuguesa de Estomatologia e Medicina Dentária
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos