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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Usefulness of 18F-FDG PET/CT in recurrent basal cell carcinoma: Report of a case
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Vol. 35. Issue 2.
Pages 124-126 (March - April 2016)
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Vol. 35. Issue 2.
Pages 124-126 (March - April 2016)
Clinical note
Usefulness of 18F-FDG PET/CT in recurrent basal cell carcinoma: Report of a case
Utilidad de la 18F-FDG PET/TC en el carcinoma basocelular recurrente: a propósito de un caso
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S. Ayalaa,b,
Corresponding author
sandra.ayala.07@hotmail.com

Corresponding author.
, P. Perlazaa, S. Puigc, E. Pratsb, S. Vidal-Sicarta
a Servei de Medicina Nuclear (CDIC), Hospital Clínic Barcelona, Spain
b Servicio de Medicina Nuclear, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
c Unitat de Melanoma, Servei de Dermatologia (ICMiD), Hospital Clínic de Barcelona, Spain
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Abstract

We analyze the case of a patient with left periorbital infiltrating basal cell carcinoma treated with surgical excision in October 2010. Surgery included orbital exenteration and reconstruction using skin graft and radiotherapy. In May 2013 a MR imaging showed a mass in the left orbital fossa, suggesting a recurrence in the graft. A basal cell carcinoma recurrence with perineural invasion was confirmed in the biopsy. On 18F-FDG PET/CT performed, a hypermetabolic activity was observed in the left periorbital area with extension to surrounding sinus and bones.

The use of 18F-FDG PET/CT in patients with advanced basal cell carcinoma has not been fully explored due to the rarity of this entity. This case demonstrates the usefulness of this technique to determine the extent of non-melanocytic recurrent skin tumors, and its value in the staging and treatment control, supporting the incorporation of 18F-FDG PET/CT in the management of advanced basal cell carcinoma.

Keywords:
Basal cell carcinoma
Local recurrence
PET/CT
Skin cancer
Resumen

Analizamos el caso de un paciente con carcinoma basocelular infiltrante periorbitario izquierdo, tratado con exéresis quirúrgica en Octubre de 2010 incluyendo exanteración orbitaria, reconstrucción mediante injerto cutáneo y radioterapia. En Mayo de 2013 una RM demostró una masa en la fosa orbitaria izquierda, sugestiva de recidiva en el injerto. Un carcinoma basocelular morfeiforme, con invasión perineural fue confirmado mediante biopsia. Se realizó 18F-FDG PET/TC donde se observó actividad hipermetabólica en zona periorbitaria izquierda con infiltración de dicho espacio, senos paranasales y huesos circundantes.

El uso de 18F-FDG PET/TC, en pacientes con carcinoma basocelular avanzado no ha sido explorado completamente debido a la rareza de esta entidad. Este caso demuestra la utilidad de esta técnica para detectar y establecer la extensión de tumores recurrentes de piel, no melanociticos y su valor en la estadificación y control del tratamiento, apoyando la incorporación de la 18F-FDG PET/TC en el manejo del carcinoma basocelular avanzado.

Palabras clave:
Carcinoma basocelular
Recurrencia local
PET/TC
Cáncer cutáneo

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