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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Uncommon isolated distant subcutaneous tissue and skeletal muscle metastasis fro...
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Vol. 35. Issue 1.
Pages 38-41 (January - February 2016)
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Vol. 35. Issue 1.
Pages 38-41 (January - February 2016)
Clinical note
Uncommon isolated distant subcutaneous tissue and skeletal muscle metastasis from oesophageal cancer diagnosed by 18F-FDG PET/CT
Infrecuente metastatización a distancia exclusiva subcutánea y muscular de cáncer de esófago diagnosticada por 18F-FDG PET/CT
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M.L. Domínguez
Corresponding author
mluzovi@yahoo.es

Corresponding author.
, J.I. Rayo, J. Serrano, J.R. Infante, L. García, M. Moreno
Servicio de Medicina Nuclear, Hospital Universitario “Infanta Cristina”, Badajoz, Spain
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Abstract

Distant soft-tissue metastases (subcutaneous tissues and skeletal muscle) are extremely rare, specially in esophageal carcinoma. We describe a patient who was treated for oesophageal adenocarcinoma 2.5 years before. A PET/CT was performed showing metastatic spread because of a solitary focus of increased tracer uptake corresponding one subcutaneous node in the upper abdomen. An excisional biopsy proved to be a metastasis from the carcinoma. Restaging 18F-FDG PET/CT study was performed 2 years later demonstrating some focus of increased uptake within several muscles as isolated distant hematogenous spread of metastases, as they were histopathologically confirmed.

As most of soft-tissue metastases are asymptomatic, the physicians should recommend histopathological study of focus of FDG uptake at subcutaneous tissues and/or skeletal muscles, because they may be the first sign of disease expansion so therapeutic management of these patients could be changed.

Keywords:
Esophageal cancer
PET/CT 18F-FDG
Subcutaneous metastasis
Muscular metastasis
Resumen

Las metástasis en partes blandas (tejido celular subcutáneo y músculo esquelético) son extremadamente raras, especialmente en cáncer de esófago. Presentamos un varón con antecedente de adenocarcinoma de esófago tratado 2,5 años antes, con hallazgo en 18F-FDG PET/TC de afectación metastásica a distancia exclusiva en un nódulo subcutáneo en pared abdominal, con confirmación anatomopatológica tras su resección. En nuevo PET-TAC 18F-FDG realizado 2 años después se objetivó nueva afectación a distancia pero exclusiva en musculatura esquelética, también confirmada histológicamente.

Como las lesiones en partes blandas frecuentemente son asintomáticas, ante el hallazgo en un estudio PET de lesiones subcutáneas y/o musculares hipermetabólicas debemos recomendar su estudio histológico, ya que pueden tratarse del primer signo de una metastatización a distancia cambiando radicalmente el manejo terapéutico del paciente.

Palabras clave:
Cáncer esófago
PET-TAC 18F-FDG
Metástasis subcutánea
Metástasis muscular

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