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Vol. 34. Issue 5.
Pages 317-320 (September - October 2015)
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Vol. 34. Issue 5.
Pages 317-320 (September - October 2015)
Clinical note
Sentinel lymph node biopsy in pediatric melanoma. A case series
Biopsia selectiva de ganglio centinela de melanoma en niños. Serie de casos
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M. Sánchez Aguilara,
Corresponding author
marta231087@hotmail.com

Corresponding author.
, R.M. Álvarez Péreza, F.J. García Gómeza, P. Fernández Ortegab, I. Borrego Doradoa
a Servicio de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Sevilla, Spain
b Servicio de Dermatología y Venereología, Hospital Universitario Virgen del Rocío, Sevilla, Spain
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Table 1. General parameters used in the preparation and performance of the lymphoscintigraphic, SPECT/CT and PET/CT studies in pediatric patients with melanoma.
Abstract

The incidence of melanoma in children is uncommon, being particularly rare in children under 10 years-old. However, this disease is increasing by a mean of 2% per year. As in adults, the lymph node status is the most important prognostic factor, crucial to performing the selective sentinel lymph node biopsy (SLNB). We report 3 cases of pediatric patients of 3-, 4- and 8-years-old, in which SLNB was performed for malignant melanoma. Pediatric age implies greater technical difficulty to the scintigraphy scan due to poor patient cooperation, with mild sedation required in some cases, and only being able to acquire planar images in other cases. SPECT/CT was only performed in the oldest patient. In our cases, SLNB was useful for selecting the least invasive surgery in order to reduce morbidity.

Keywords:
Melanoma
Pediatric
Sentinel lymph node biopsy
Single photon emission computed tomography
Resumen

La incidencia del melanoma en la edad pediátrica es baja, siendo particularmente raro en menores de 10 años. No obstante, se ha constatado un aumento de la misma con un incremento promedio del 2% por año. Al igual que en los adultos, la afectación ganglionar es el factor pronóstico más relevante, por ello es fundamental la realización de la biopsia selectiva del ganglio centinela (BSGC). Presentamos 3 casos de pacientes en edad pediátrica de 3, 4 y 8 años, en los que se realizó BSGC, por melanoma maligno. La edad pediátrica confiere una mayor dificultad técnica al estudio linfogammagráfico por la escasa colaboración del paciente, precisando en algunos casos sedación superficial para su realización y pudiéndose adquirir únicamente en la mayoría de los casos imágenes sectoriales. Solamente en la paciente de mayor edad pudo practicarse SPECT/TC complementario. En nuestros casos la BSGC fue eficaz para poder seleccionar el tratamiento quirúrgico menos invasivo reduciendo así la morbilidad.

Palabras clave:
Melanoma
Pediátrico
Biopsia selectiva del ganglio centinela
Tomografía por emisión de fotón único

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