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Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Extensive hypermetabolic pattern of brown adipose tissue activation on 18F-FDG P...
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Vol. 32. Issue 6.
Pages 397-399 (November - December 2013)
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Vol. 32. Issue 6.
Pages 397-399 (November - December 2013)
Clinical note
Extensive hypermetabolic pattern of brown adipose tissue activation on 18F-FDG PET/CT in a patient diagnosed of catecholamine-secreting para-vesical paraganglioma
Extenso patrón hipermetabólico por activación de la grasa parda en un paciente diagnosticado de paraganglioma para-vesical secretor de catecolaminas explorado mediante 18F-FDG PET/TC
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J. Banzoa,
Corresponding author
, M.A. Ubietoa, M.F. Berisab, A. Andrésc, M.L. Mateod, L. Tardínc, A. Parrac, P. Razolac, E. Pratsc
a Unidad de Medicina Nuclear, Grupo Hospitalario Quirón, La Floresta, Zaragoza, Spain
b Servicio de Nefrología, Hospital Obispo Polanco, Teruel, Spain
c Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain
d Servicio de Neumología, Hospital Obispo Polanco, Teruel, Spain
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Abstract

The widespread use of 18F-FDG PET-CT scanning in oncological patients has allowed to demonstrate the existence of metabolically active brown fat, also called brown adipose tissue (BAT), in adult humans, and specifying its anatomical distribution in vivo. As physiological determinants to BAT 18F-FDG uptake has been identified gender, age, temperature, and body mass index. We have observed extensive activation of the BAT, including the mesenteric region, in a patient with a catecholamine-secreting para-vesical paranganglioma. The extensive BAT activation could be secondary to adrenergic stimulation due to excess of circulating norepinephrine concentration.

Keywords:
Mesenteric brown adipose tissue
Para-vesical paraganglioma
18F-FDG PET/CT
Resumen

El uso generalizado de la exploración 18F-FDG PET-TC en pacientes de cáncer ha permitido demostrar la existencia de grasa parda metabólicamente activa, también llamada tejido adiposo pardo (TAP), en sujetos humanos adultos, y conocer su distribución anatómica in vivo. Como determinantes fisiológicos de la captación de 18F-FDG por el TAP se han identificado el sexo, la edad, la temperatura y el índice de masa corporal. Hemos observado una extensa activación del TAP, incluyendo la región mesentérica, en un paciente con un paranganglioma paravesical secretor de catecolaminas. La activación extensa del TAP podría ser secundaria a la estimulación adrenérgica por un exceso de la concentración de noradrenalina circulante.

Palabras clave:
Tejido adiposo pardo mesentérico
Paraganglioma paravesical
18F-FDG PET/TC

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