Buscar en
Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
Toda la web
Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Effectivity and clinical impact of 18F-FDG PET in the diagnosis of unsuspected s...
Journal Information
Vol. 32. Issue 3.
Pages 139-145 (May - June 2013)
Share
Share
Download PDF
More article options
ePub
Visits
774
Vol. 32. Issue 3.
Pages 139-145 (May - June 2013)
Original article
Effectivity and clinical impact of 18F-FDG PET in the diagnosis of unsuspected second primary tumors
Efectividad e impacto clínico de la PET-18F-FDG en el diagnóstico de segundos tumores primarios insospechados
Visits
...
L. Caballero Gullón??
Corresponding author
, I. Borrego Dorado, R. Vázquez Albertino
Unidad de Diagnóstico por la Imagen, Servicio de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Sevilla, Spain
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (2)
Tables (2)
Table 1. Reasons for consultation.
Table 2. Patients suspected of having second/third primary tumors with histological confirmation.
Show moreShow less
Abstract
Objective

This study is aimed to determine the capacity and clinical impact of the 18F-FDG-PET to detect previously unsuspected second primary tumors.

Materials and methods

This is a retrospective cross-sectional study of 1984 consecutive scans performed between March 2004 and March 2005, identifying those studies that had reported the presence of hypermetabolic lesions, that had not been previously suspected or detected and that could be suggestive of second primary tumors. Diagnosis was made histopathologically or by clinical and radiological follow-up for a period exceeding one year.

Results

62 findings suggestive of second primary tumors were detected in 58 patients (3.1%). The reasons for the study for this group of patients were diverse, the most common being the differential diagnosis of solitary pulmonary nodules. A total of 43.5% of lesions were not followed-up. We confirmed the existence of 35 lesions, either by pathology study (21 lesions, 13 second primary tumors, the incidence in our population was 0.65%) or clinical and radiological follow-up (14 lesions, none of which corresponded to second primary tumors). The total clinical impact was the discovery of unexpected 14 lesions in 12 patients.

Conclusion

The presence of second primary tumors on 18F-FDG-PET is relatively common. These lesions should be monitored clinically for accurate diagnosis. In a high percentage, they correspond to unexpected second primary tumors in an early stage and therefore amenable to curative treatment or for which tumor treatment planning may be modified.

Keywords:
18F-FDG-PET
Incidental
Oncology
Resumen
Objetivo

Evaluar la capacidad e impacto clínico de la PET-18F-FDG en el diagnóstico de segundos tumores primarios malignos inesperados.

Material y métodos

Estudio retrospectivo transversal descriptivo de 1.984 exploraciones PET-18F-FDG consecutivas realizadas entre marzo de 2004 y marzo de 2005, identificándose aquellos estudios en los que se había informado de la presencia de lesiones hipermetabólicas, no sospechadas ni detectadas previamente y que pudiesen ser sugestivas de segundos tumores primarios. Se obtuvo un diagnóstico histopatológico o mediante seguimiento clínico-radiológico durante un período de tiempo superior a un año.

Resultados

Se detectaron 62 hallazgos sugestivos de incidentalomas en 58 pacientes (3,1%). Los motivos de indicación en este grupo de pacientes fueron diversos siendo los más frecuentes el diagnóstico diferencial de benignidad vs malignidad de nódulos pulmonares solitarios. Un 43,5% de las lesiones no tuvieron seguimiento. Se confirmó la existencia de 35 lesiones, bien mediante estudio anatomopatológico (21 lesiones, 13 incidentalomas, la incidencia en nuestra población fue del 0,65%) o por seguimiento clínico-radiológico (14 lesiones, ninguna de ellas correspondió a segundos tumores primarios). El impacto clínico total fue el hallazgo de 14 lesiones no esperadas en 12 pacientes.

Conclusiones

La presencia de incidentalomas en la PET-18F-FDG es relativamente frecuente. Estas lesiones deben ser objeto de seguimiento clínico para su diagnóstico exacto. En un alto porcentaje se corresponden con segundos tumores primarios inesperados en fase incipiente y, por lo tanto, susceptibles de tratamiento curativo o que pueden modificar la planificación del tratamiento del tumor ya conocido.

Palabras clave:
PET-18F-FDG
Incidental
Oncología

Article

These are the options to access the full texts of the publication Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos