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Vol. 32. Issue 6.
Pages 378-386 (November - December 2013)
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Vol. 32. Issue 6.
Pages 378-386 (November - December 2013)
Continuing education
Update on the use of PET radiopharmaceuticals in inflammatory disease
Actualización del uso de radiotrazadores PET en patología inflamatoria
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2945
I. Martínez-Rodríguez
Corresponding author
mimartinez@humv.es

Corresponding author.
, J.M. Carril
Servicio de Medicina Nuclear, Hospital Universitario «Marqués de Valdecilla», Universidad de Cantabria, Santander, Spain
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Table 1. PET radiotracers in the study of inflammatory disease.
Table 2. Inflammatory diseases in which different PET radiotracers are used.
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Abstract

The use of molecular imaging with PET/CT technology using different radiotracers, especially the 18F-FDG is currently spreading beyond the area of oncology, the most interest being placed on inflammatory and infectious diseases. This article presents a review of its contribution in different inflammatory conditions in the context of structural and conventional nuclear medicine imaging. Special emphasis is placed on the more significant diseases such as large-vessel vasculitis, sarcoidosis, rheumatoid arthritis and inflammatory bowel disease and the study of the atheroma plaque.

Keywords:
Inflammation
18F-FDG PET/CT
Large vessel vasculitis
Sarcoidosis
Rheumatoid arthritis
Atheromatosis
Resumen

En la actualidad el uso de la imagen molecular con tecnología PET/TC con diferentes radiotrazadores, en especial la 18F-FDG, se está extendiendo más allá del ámbito de la oncología, siendo las enfermedades inflamatorias e infecciosas unas de las que más interés están despertando. En este artículo se hace una revisión de su aplicación y aportación en diferentes patologías inflamatorias en el contexto de las técnicas de imagen estructurales y de medicina nuclear convencional. Se hace especial énfasis en las de mayor entidad como son la vasculitis de grandes vasos, la sarcoidosis, la artritis reumatoide, la enfermedad inflamatoria intestinal y el estudio de la placa de ateroma.

Palabras clave:
Inflamación
18F-FDG PET/TC
Vasculitis de grandes vasos
Sarcoidosis
Artritis reumatoide
Ateromatosis

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