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Vol. 48. Issue 5.
Pages 469-474 (September - October 2020)
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Vol. 48. Issue 5.
Pages 469-474 (September - October 2020)
DOI: 10.1016/j.aller.2019.10.007
Predictors for the prescription of albuterol in infants hospitalized for viral bronchiolitis
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S.M. Piña-Hincapiea, M.P. Sossa-Briceñob, C.E. Rodriguez-Martineza,c,
Corresponding author
carerodriguezmar@unal.edu.co

Corresponding author.
a Department of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia
b Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia
c Department of Pediatric Pulmonology and Pediatric Critical Care Medicine, School of Medicine, Universidad El Bosque, Bogota, Colombia
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Tables (2)
Table 1. Demographic characteristics and clinical information of the patients included in the study, according to the prescription of albuterol.
Table 2. Predictors for the prescription of albuterol in infants hospitalized for viral bronchiolitis determined through multivariate analysis.
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Abstract
Introduction and objectives

Despite the recommendation against routine use of inhaled bronchodilators in infants with viral bronchiolitis given in the main clinical practice guidelines (CPGs) on viral bronchiolitis, albuterol is widely prescribed to patients with this disease. The aim of this study was to identify predictors of prescription of albuterol in a population of infants hospitalized for viral bronchiolitis.

Material and methods

An analytical cross-sectional study performed during the period from March 2014 to August 2015, in a random sample of patients <2 years old hospitalized in the Fundacion Hospital La Misericordia, a hospital located in Bogota, Colombia. After reviewing the electronic medical records, we collected demographic, clinical, and disease-related information, including prescription of albuterol at any time during the course of hospitalization as the outcome variable.

Results

For a total of 1365 study participants, 1042 (76.3%) were prescribed with albuterol therapy. After controlling for potential confounders, it was found that age (OR 1.11; CI 95% 1.08–1.15; p<0.001), and a prolonged length of stay (LOS) (OR 1.93; CI 95% 1.44–2.60; p<0.001) were independent predictors of prescription of albuterol in our sample of patients. By contrast, albuterol prescription was less likely in the post-guideline assessment period (OR 0.41; CI 95% 0.31–0.54; p<0.001), and in infants with RSV isolation (OR 0.71; CI 95% 0.52–0.97; p=0.035).

Conclusions

Albuterol was highly prescribed in our population of inpatients with the disease. The independent predictors of prescription of albuterol in our sample of patients were age, implementation of a CPG on viral bronchiolitis, RSV isolation, and LOS.

Keywords:
Albuterol
Bronchiolitis
Clinical practice variations
Quality of care

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