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Journal Information
Vol. 48. Issue 1.
Pages 56-61 (January - February 2020)
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Vol. 48. Issue 1.
Pages 56-61 (January - February 2020)
Original Article
DOI: 10.1016/j.aller.2019.04.004
Direct medical costs of RSV-related bronchiolitis hospitalizations in a middle-income tropical country
C.E. Rodriguez-Martineza,b,
Corresponding author

Corresponding author.
, M.P. Sossa-Briceñoc, J.A. Castro-Rodriguezd
a Department of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia
b Department of Pediatric Pulmonology and Pediatric Critical Care Medicine, School of Medicine, Universidad El Bosque, Bogota, Colombia
c Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia
d Division of Pediatrics, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile
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Tables (3)
Table 1. Diagnostic test most frequently ordered, and the medications most often prescribed stratified by the hospital service in which the patient was admitted.a
Table 2. Unit costs of direct medical items and health care services.a
Table 3. Total median costs associated with RSV-related bronchiolitis stratified by the hospital service in which the patient was admitted.a
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Introduction and objectives

With the objective of making informed decisions on resource allocation, there is a critical need for studies that provide accurate information on hospital costs for treating respiratory syncytial virus (RSV)-related bronchiolitis, mainly in middle-income countries (MICs). The aim of the present study was to evaluate the direct medical costs associated with bronchiolitis hospitalizations caused by infection with RSV in Bogota, Colombia.

Material and methods

We reviewed the available electronic medical records (EMRs) for all infants younger than two years of age who were admitted to the Fundacion Hospital de La Misericordia with a discharge principal diagnosis of RSV-related bronchiolitis over a 24-month period from January 2016 to December 2017. Direct medical costs of RSV-related bronchiolitis were retrospectively collected by dividing the infants into three groups: those requiring admission to the pediatric ward (PW) only, those requiring admission to the pediatric intermediate care unit (PIMC), and those requiring to the pediatric intensive care unit (PICU).


A total of 89 patients with a median (IQR) age of 7.1 (3.1–12.2) months were analyzed of whom 20 (56.2%) were males. Overall, the median (IQR) cost of infants treated in the PW, in the PIMC, and in the PICU was US$518.0 (217.0–768.9) vs. 1305.2 (1051.4–1492.2) vs. 2749.7 (1372.7–4159.9), respectively, with this difference being statistically significant (p<0.001).


The present study helps to further our understanding of the economic burden of RSV-related bronchiolitis hospitalizations among infants of under two years of age in a middle-income tropical country.

Hospitalization costs
Length of stay
Respiratory syncytial virus


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