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Revista Española de Anestesiología y Reanimación (English Edition) Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-bloc...
Journal Information
Vol. 72. Issue 2.
(February 2025)
Case report
Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient
Parada cardiorrespiratoria durante la cirugía de trasplante hepático: implicación del beta-bloqueo perioperatorio en el paciente cirrótico
R.C. Vela Pascual
Corresponding author
r.velapascual@gmail.com

Corresponding author.
, J.M. Pérez Peña, A. Elvira Rodríguez, M. Power Esteban, C. Jimeno Fernández, J.A. Varela Cabo
Hospital Universitario Gregorio Marañón, Madrid, Spain
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Table 1. Causes of bradycardia with intraoperative haemodynamic repercussion.
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Table 2. Mechanisms of beta-blocker toxicity.
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Abstract

Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%.

Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed.

We introduce the case of a cirrhotic patient who received beta-blocker therapy in the preoperative period and who experienced intraoperative CPA during LT surgery, which was successfully resolved through advanced cardiopulmonary resuscitation (CPR) maneuvers and specific treatment for beta-blocker toxicity (calcium and glucagon).

Keywords:
Liver transplantation
Asystole
Beta-blockers
Glucagon
Resumen

La cirugía de trasplante hepático (TH) presenta una incidencia de parada cardiorrespiratoria (PCR) intraoperatoria en torno al 5%. Los pacientes que sufren PCR durante dicha intervención presentan una supervivencia reducida cercana al 50%.

La mayoría de PCR se producen en la fase neohepática debido al síndrome de reperfusión, pero no siempre es esta la causa subyacente y debemos realizar un diagnóstico diferencial amplio.

Presentamos el caso de un paciente cirrótico en tratamiento con betabloqueantes que presentó PCR durante el TH, de la que se recuperó tras reanimación cardiopulmonar (RCP) avanzada y tratamiento específico para la toxicidad por betabloqueantes (calcio y glucagón).

Palabras clave:
Trasplante hepático
Asistolia
Beta-bloqueantes
Glucagón

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