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European Journal of Psychiatry Association between psychological pain and suicidal behaviour in a cohort of pat...
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Vol. 39. Issue 3.
(July - September 2025)
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Vol. 39. Issue 3.
(July - September 2025)
Original article
Association between psychological pain and suicidal behaviour in a cohort of patients at high risk of suicide
Ana Pérez-Balaguera, Inmaculada Peñuelas-Calvob,c,d,e,
Corresponding author
, Ana María de Granda-Beltránf,g, Jimena María Merayo-Canof,g, Berta Ezquerraf,g, Adrián Alacreu-Crespoh, Enrique Baca-Garcíaf,g,i,j,k,l,m,n, Alejandro Porras-Segoviag,i
a Department of Psychiatry, Hospital Universitario El Escorial, Madrid, Spain
b Department of Child and Adolescent Psychiatry, Hospital Universitario 12 de Octubre, Madrid, Spain
c Health Research Institute Hospital 12 de Octubre (i+12 Institute), Madrid, Spain
d Department of Psychiatry, Universidad Complutense de Madrid, Madrid, Spain
e CIBERSAM-ISCIII (Biomedical Research Networking Centre for Mental Health/Carlos III Health Institute), Spain
f Department of Psychiatry, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
g Mental Health Research Group, Health Research Institute Jiménez Díaz Foundation, Madrid, Spain
h Department of Psychology, University of Zaragoza, Zaragoza, Spain
i Department of Psychiatry, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, Spain
j Department of Psychiatry, Hospital Universitario Infanta Elena, Valdemoro, Madrid, Spain
k Department of Psychiatry, Hospital General de Villalba, Villalba, Madrid, Spain
l Department of Psychiatry, Nîmes University Hospital, Nîmes, France
m CIBERSAM, Research Group CB/07/09/0025, Madrid, Spain
n Department of Psychiatry, Universidad Autónoma de Madrid, Madrid, Spain
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Tables (4)
Table 1. Sociodemographic characteristics.
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Table 2. Suicide events throughout follow-up.
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Table 3. Univariate Cox regression.
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Table 4. Multivariate Cox regression.
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Abstract
Background and Objectives

Suicide is a major global public health issue. Pain, both psychological and physical, are potential risks factors for suicidal behaviour (SB). This study aims to explore the relationship between psychological and physical pain and SB in individuals at high risk of suicide.

Methods

This prospective cohort study included 322 participants recruited from emergency departments, psychiatric inpatient units, and outpatient mental health services in two hospitals in Madrid (Spain). Participants completed assessments at baseline and six months. Psychological and physical pain were measured using validated Visual Analog Scales (VAS). The primary outcome was the occurrence of suicidal events, documented through medical records and follow-up interviews. Kaplan-Meier survival analyses estimated the occurrence of suicidal events after 6 months of follow-up. Factors associated with suicidal events were analysed using univariate and multivariate Cox regression models to identify independent predictors of SB.

Results

Severe psychological pain in the previous 15 days was significantly associated with an increased risk of SB (p = 0.017), independently of depression severity. Younger age also emerged as a significant risk factor. No association was found between physical pain and SB.

Conclusions

Psychological pain is a key predictor of SB and should be a focus in suicide risk assessments. Further research is needed to improve measurement tools and develop targeted interventions in order to treat psychological pain effectively.

Keywords:
Psychological pain
Physical pain
Suicide
Suicide attempt
Suicide ideation

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