Buscar en
Enfermedades Infecciosas y Microbiología Clínica
Toda la web
Inicio Enfermedades Infecciosas y Microbiología Clínica Infecciones por Kingella kingae en la edad pediátrica
Información de la revista
Vol. 29. Núm. S3.
Programa Externo de Control de Calidad SEIMC. Año 2009
Páginas 29-32 (Marzo 2011)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 29. Núm. S3.
Programa Externo de Control de Calidad SEIMC. Año 2009
Páginas 29-32 (Marzo 2011)
Acceso a texto completo
Infecciones por Kingella kingae en la edad pediátrica
Kingella kingae infections in the pediatric age
Visitas
5686
M. Carmen Otero Reigadaa,
Autor para correspondencia
otero_car@gva.es

Autor para correspondencia.
, Laura Fernández Silveiraa, Sergio Negre Policarpoa, M. Amparo Pérez Tamarita, Ana Ortí Martína, María Santos Durántezb
a Unidad de Pediatría Infecciosa, Hospital Infantil La Fe, Valencia, España
b Servicio de Microbiología Clínica, Hospital La Fe, Valencia, España
Este artículo ha recibido
Información del artículo
Resumen

Las infecciones por Kingella kingae han despertado recientemente un importante interés debido al mayor número de casos identificados. Aunque se considera un patógeno emergente, probablemente el mejor conocimiento de la bacteria, las mejores técnicas para el diagnóstico microbiológico y una mayor concienciación de los clínicos frente a este microorganismo justifican este aumento de casos descritos. K. kingae es un cocobacilo aerobio gramnegativo que presenta especial tropismo por el tejido osteoarticular, endocardio y espacio vascular. Las infecciones descritas con mayor frecuencia son osteomielitis, artritis séptica, endocarditis y bacteriemia. Los antimicrobianos de elección son penicilinas y cefalosporinas. Se revisa en este artículo la bibliografía relacionada con este microorganismo.

Palabras clave:
Kingella kingae
Infecciones osteoarticulares
Endocarditis
Artritis
Patógeno emergente
Abstract

Kingella kingae infections have aroused great interest in the last few years because of the increasing number of identified cases. Although considered an emerging pathogen, the increase in diagnosis of these infections can probably be explained by better knowledge of the bacteria, improved microbiological diagnostic techniques and greater awareness among clinicians. K. kingae is an aerobic cocobacillus with high tropism for osteoarticular tissue, endocardium, and vascular space. This pathogen mainly produces osteomyelitis, endocarditis, septic arthritis and bacteriemias. First choice antibiotics are penicillins and cephalosporins. This article reviews the literature on this microorganism.

Keywords:
Kingella kingae
Osteoarticular infections
Endocharditis
Arthritis
Emergin pathogen
El Texto completo está disponible en PDF
Bibliografía
[1.]
P. Yagupsky, Y. Bar-Ziv, C.B. Howard, R. Dagan.
Epidemiology, etiology and clinical features septic arthritis in children younger than 24 months.
Arch Pediatr Adolesc Med, 149 (1995), pp. 537-540
[2.]
P. Yagupsky.
Kingella kingae: from medical rarity to an emerging paediatric pathogen.
Lancet Infect Dis, 4 (2004), pp. 358-367
[3.]
I. Araya, R. Camponovo.
Kingella Kingae.
Rev Chil Infect, 23 (2006), pp. 155
[4.]
I. Etxebarria Foronda, X. Giokoetxea Uriarte, L. Sanado Lamppreave.
Infecciones osteoarticulares en niños por Kingella kingae.
Patología del aparato locomotor, 4 (2006), pp. 187-192
[5.]
A.C. Seña, P. Seed, B. Nicholson, M. Joyce, C.K. Cunningham.
Kingella Kingae endocarditis and a cluster investigation among daycare attendees.
Pediatr Infect Dis J, 29 (2010), pp. 86-88
[6.]
E.M. Sordillo, M. Rendel, R. Sood, J. Belinfanti, O. Murria, D. Brook.
Septicemia due to beta lactamase positive Kingella kingae (setter).
Clin Infect Dis, 17 (1993), pp. 818-819
[7.]
A. Slonim, E.S. Walker, E. Mishori, N. Porat, R. Dagan, P. Yagupsky.
Person-to-person transmission of Kingella kingae among day care center attendees.
J Infect Dis, 178 (1998), pp. 1843-1846
[8.]
J. Amir, P. Yagupsky.
Invasive Kingella kingae infection associated with stomatitis in children.
Pediatr Infect Dis, 17 (1998), pp. 757-758
[9.]
G. Duvnov-Raz, M. Ephros, B.Z. Garty, Y. Schlesinger, A. Maayan-Metzger, J. Hasson, et al.
Invasive pediatric Kingella kingae infections. A Nationwide Collaborative Study.
Pediatric Infect Dis J, 29 (2010), pp. 639-643
[10.]
K.M. Kiang, R. Lynfield.
Kingella kingae: an emerging pathogen of acute osteoarticular infections in children: in reply.
Pediatrics, 117 (2006), pp. 249-250
[11.]
P. Saphyakhajon, G. Greene.
Kingella kingae: an emerging pathogen of acute osteoarticularinfections in children.
Pediatrics, 117 (2006), pp. 249
[12.]
K.M. Kiang, F. Ogunmodede, B.A. Juni, D.J. Boxrud, A. Glennen, J.M. Bartkus, et al.
Outbreak of osteomyelitis/septic arthitis caused by Kingella kingae among child care center attendees.
Pediatrics, 116 (2005), pp. e206-e213
[13.]
P. Yagupsky, Y. Erlich, S. Ariela, R. Trefler, N. Porat.
Outbreak of Kingella kingae eskeletal system infections in children in daycare.
Pediatr Infect Dis J, 25 (2006), pp. 526-532
[14.]
S. Chometon, Y. Benito, M. Chaker, S. Boisset, C. Ploton, J. Bérard, et al.
Specific realtime polymerase chain reaction places Kingella kingae as the most common cause of osteoarticular infections in young children.
Pediatr Infect Dis J, 26 (2007), pp. 377-381
[15.]
P. Yaguosky, O. Katz, N. Peled.
Antibiotic susceptibility of Kingella kingae isolates from respiratory Carriers and patients with invasive infections.
J Antimicrob Chemother, 47 (2001), pp. 191-193
[16.]
J.M. Davis, M.M. Peel.
Osteomyelitis and septic arthritis caused by Kingella kingae.
J Clin Pathol, 5 (1982), pp. 219-222
[17.]
J.J. Goutzmanis, G. Gonis, G.L. Gilbert.
Kingella kingae infection: ten cases and a review of the literature.
Pediatr Infect Dis J, 10 (1991), pp. 677-683
[18.]
P. Yagupsky, R. Dagan, C.B. Howard, M. Einhorn, I. Kassis, A. Simu.
Clinical features and epidemiology of invasive Kingella kingae infections in Southern Israel.
Pediatrics, 92 (1993), pp. 800-804
[19.]
K. Mouline, J. Merckx, C. Glorian, P. Berche, A. Ferroni.
Osteoarticular infections caused by Kingella kingae in children: contribution of polymerase chain reaction to the microbiologic diagnosis.
Pediatr Infect Dis J, 22 (2003), pp. 837-839
[20.]
D.W. Lundy, D.K. Kehl.
Increasing prevalence of Kingella kingae in osteoarticular infections in young children.
J Pediatr Orthop, 18 (1998), pp. 262-267
[21.]
M. Pons Odena, E. Gózales Pascual, J. Ros Viladoms, A. Gene Giralt, E. Mary Llanas, R. Huguet Carol.
Infección osteoarticular por Kingella kingae: a propósito de 2 casos.
An Esp Pediatr, 17 (1999), pp. 512-515
[22.]
M.M. Shelton, M.P. Nachtigal, D.A. Yngve, W.A. Herndon, H.D. Riley.
Kingella kingae osteomyelitis: report of two cases involving the epiphisis.
Pediatr Infect Dis J, 7 (1988), pp. 421-424
[23.]
E. Garron, E. Viehweger, F. Launay, J.M. Guillaume, J.L. Jouve, G. Bonilli.
Nontouberculous spondylodiscitis in children.
J Pediatr Orthop, 22 (2002), pp. 321-328
[24.]
E. Ruiz, A. Pérez, F. Asensi, M.C. Otero, M. Santos.
Espondilitis por Kingella kingae en una niña de 10 años.
Enferm Infecc Microbiol Clin, 18 (2000), pp. 363-364
[25.]
H. Birgisson, O. Steingrimsson, T. Guadnason.
Kingella kingae infection in paediatric patiens: 5 cases of septic arthritis, osteomyelitis and bacteraemia.
Scand J Infect Dis, 29 (1997), pp. 495-498
[26.]
M. Lacour, M. Duarte, A. Beutler, R. Auckenthaler, S. Suter.
Osteoarticular infections due to Kingella kingae in children.
Eur J Pediatr, 150 (1991), pp. 612-618
[27.]
L. Wells, N. Rutter, F. Donald.
Kingella kingae endocarditis in a sixteen-month-old child.
Pediatr Infect Dis J, 20 (2001), pp. 454-455
[28.]
B. Feber, E. Bruckheimer, Y. Schlesinger, I. Berger, J. Glaser, O. Olsha, et al.
Kingella kingae endocarditisin a chil with hair cartilague hypoplasia.
Pediatr Cardiol, 18 (1997), pp. 445-446
[29.]
C.E. Christensen, G.C. Emmanuollides.
Brief recording: bacterial endocarditis due to “Moraxella new especies” 1.
N Englan J Med, 277 (1967), pp. 803-804
[30.]
W.L. Lee, E.C. Dooling.
Acute Kingella kingae endocarditis with recurrent cerebral emboli in a child with mitral prolapse.
Ann Neurol, 16 (1984), pp. 88-89
[31.]
H. Sarda, D. Ghazali, M. Thibault, F. Leturdu, C. Adams, H. Le Loc’h.
Multifocal invasive Kingella kingae infection.
Arch Pediatr, 5 (1988), pp. 159-162
[32.]
L. Odum, K.T. Jensen, T.D. Slotsbjerg.
Endocarditis due to Kingella kingae.
Eur J Clin Microbiol, 3 (1984), pp. 263-264
[33.]
E.F. Berbari, F.R. Cockerill, J.M. Steckelber.
Infective endocarditis due to inusual or fastidious microorganims.
Mayo Clin Proc, 72 (1997), pp. 532-542
[34.]
H. Rodríguez Bouza, J. De la Fuente Aguado, M. Rubianes González, M. Crespo Casal, B. Sopeña Pérez-Argüelles.
Endocarditis por Kingella kingae.
An Med Interna (Madrid), 18 (2001), pp. 655-656
[35.]
G. Doubnov-Raz, O. Scheuerman, G. Chodick, Y. Finkelstein, Z. Samra, B.Z. Garty.
Invasive Kingella kingae infection in children: clinical and laboratory characteristics.
Pediatrics, 122 (2008), pp. 1305-1309
[36.]
J.L. Goméz-Garcés, J. Oteo, G. García, J.L. Alós.
Kingella kingae pneumonia: a rare pathology or a pathology rarely diagnosed?.
Clin Microbiol Newsl, 23 (2001), pp. 192-193
[37.]
D.H. Gremillon, G.E. Craford.
Measles pneumoniain young adults. An analysis of 106 cases.
Am J Med, 71 (1981), pp. 539-542
[38.]
A. Reekmans, M. Noppen, A. Naessens, W. Vincken.
A rare manifestation of 135 Kingella kingae infection.
Eur J Intern Med, 11 (2000), pp. 343-344
[39.]
T. Mollee, P. Kelly, M. Tilse.
Isolation of Kingella kingae from a corneal ulcer.
J Clin Microbial, 30 (1992), pp. 2516-2519
[40.]
P.A. Van Damme, C.M. Van Herpen, J.F. Meis.
An adult caseof oral infection with Kingella kingae.
Int J Oral Maxilofac Surg, 33 (2004), pp. 105-107
[41.]
B. Ilharreborde, P.H. Bidet, M. Lorrot, J. Even, P. Mariani-Kurkdjian, S. Liguori, et al.
New real-time PCR-based method for Kingella kingae DNA detection: application to a prospective series of 89 children with acute arthritis.
J Clin Microbiol, 47 (2009), pp. 1837-1841
Copyright © 2011. Elsevier España S.L.. Todos los derechos reservados
Opciones de artículo
Herramientas
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos