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Editor, I reed the recent publication on an old woman with raised testosterone concentration with a great interest.1 Indeed, there are some recent similar case reports in the literature.2 I would like to draw attention to some condition that can result in increased testosterone without exact testosterone-related pathology. The problem on laboratory investigation should be mentioned. At least, falsely elevation can be due to heterophile antibodies from a polyclonal gammopathy in any elderly with occult myelogenous leukemia.3
References
[1]
N. Hernández, M. Maur, R. Alfayate, M.E. Torregrosa, V. Chinchilla.
A fifty-one year old woman with raised testosterone concentration.
Endocrinol Nutr, 58 (2011), pp. 50-51
[2]
V. Cheng, K. Doshi, T. Falcone, C. Faiman.
Hyperandrogenism in a postmenopausal woman: diagnostic and therapeutic challenges.
Endocr Pract, 17 (2011), pp. e1-5
[3]
D. Ramaeker, J. Brannian, K. Egland, K. McCaul, K. Hansen.
When is elevated testosterone not testosterone? When it is an immunoassay interfering antibody.
Fertil Steril, 90 (2008), pp. 886-888
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